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US4687782A Expired / Lapsed US ⏱️ 0.0 years remaining

Nutritional composition for enhancing skeletal muscle adaptation to exercise training

Assignee: MFM MARKETING Inc
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Filing: 1984-12-10
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Granted: 1987-08-18
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Expires: 2004-12-10
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Abstract

Abstract A combination of amino acids (carnitine, glutamine, isoleucine, leucine and valine) provide diet supplements which employ branched amino acids (BAA) to promote muscle adaptation to strenuous exercise. The diet supplements provide the BAA substrate which is utilized at the expense of muscle mass as well as liver protein, stimulate muscle and liver protein synthesis, contribute amino groups for the synthesis of alanine and glutamine, encourage metabolism of pyruvate to alanine, rather than to lactate, and encourage proton efflux from muscle (via glutamine).

Inventors

  • 👤 Eugene R. Brantman

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-28 15:53
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/185; A61K31/19; A61K31/195; A23; A23L; A23L33/00; A23L33/10; A23L33/17; A23L33/175

Claims Analysis

Total Claims: 27
Claim 1
Independent Claim 56 words
A method of supplementing the diet of a athlete, comprising the steps of: providing the athlete with a solution comprising an amino acid mixture consisting essentially of 0.025 grams L-carnitine, 0.5 grams L-glutamine, 0.625 grams L-isoleucine, 0.85 grams L-leucine and 0.625 grams L-valine mixed with 400 milliliters of water; and having the athlete drink the solution.
Claim 2
Independent Claim 56 words
A method of supplementing the diet of a athlete, comprising the steps of: providing the athlete with a solution comprising an amino acid mixture consisting essentially of 0.025 grams L-carnitine, 0.5 grams L-glutamine, 0.625 grams L-isoleucine, 0.85 grams L-leucine and 0.625 grams L-valine mixed with 400 milliliters of water; and having the athlete drink the solution.
Claim 3
Dependent Claim 41 words
A method as set forth in claim 1, further comprising the steps of: providing the athlete with the solution that further includes 2.5 grams of proteins being one or more selected from the group consisting of casein, soy protein and lactalbumin.
Claim 4
Dependent Claim 40 words
A method as set forth in claim 1, further comprising the steps of: providing the athlete with the solution that further includes 25.0 grams of carbohydrates being one or more selected from the group consisting of syrup solids and sucrose.
Claim 5
Dependent Claim 52 words
A method as set forth in claim 1, further comprising the steps of: providing the athlete with the solution that further includes a fat mixture consisting essentially of 2.5 grams of a mixture of sunflower oil and soybean oil in a volumetric ratio of 1:1 and of 6.0 grams of medium-chain triglycerides.
Claim 6
Dependent Claim 71 words
A method as set forth in claim 1, further comprising the steps of: providing the athlete with the solution that further includes a vitamin mixture consisting essentially of 6.0 mg. of Vitamin C, 35 microgram of Folic acid, 1.0 mg. Vitamin B1, 1.2 mg. Vitamin B2, 1.7 mg. of Niacin, 0.15 mg. Vitamin B6, 15 microgram of Biotin, 5.0 mg. of Choline, 1.0 microgram of Vitamin B12 and 0.2 mg. Pantothenate.
Claim 7
Dependent Claim 53 words
A method as set forth in claim 1, further comprising the steps of: providing the athlete with the solution that further includes a mineral mixture consisting essentially of 60 mg. of Sodium, 20 mg. of Magnesium, 200 mg. of Potassium, 50 mg. of Calcium, 75 mg. of Phosphate and 350 mg. of Chloride.
Claim 8
Dependent Claim 170 words
A method as set forth in claim 1, further comprising the steps of: providing the athlete with the solution that further includes 2.5 grams of proteins being one or more selected from the group consisting of casein, soy protein and lactalbumin; 25.0 grams of carbohydrates being one or more selected from the group consisting of syrup solids and sucrose; a fat mixture consisting essentially of 2.5 grams of a mixture of sunflower oil and soybean oil in a volumetric ratio of 1:1 and of 6.0 grams of medium-chain triglycerides; a vitamin mixture consisting essentially of 6.0 mg. of Vitamin C, 35 microgram of Folic acid, 1.0 mg. Vitamin B1, 1.2 mg. Vitamin B2, 1.7 mg. of Niacin, 0.15 mg. Vitamin B6, 15 microgram of Biotin, 5.0 mg. of Choline, 1.0 microgram of Vitamin B12 and 0.2 mg. Pantothenate; and a mineral mixture consisting essentially of 60 mg. of Sodium, 20 mg. of Magnesium, 200 mg. of Potassium, 50 mg. of Calcium, 75 mg. of Phosphate and 350 mg. of Chloride.
Claim 9
Dependent Claim 66 words
A composition adapted to be used with water as a diet supplement for facilitating the adaptation of skeletal muscle and liver to a program of strenuous exercise, comprising: an amino acid mixture consisting essentially of 0.7 to 1.8 weight percent carnitine, 1.8 to 3.4 weight percent glutamine, 23.2 to 31.2 weight percent isoleucine, 50.7 to 32.4 weight percent leucine and 23.6 to 31.2 weight percent valine.
Claim 10
Dependent Claim 66 words
A composition adapted to be used with water as a diet supplement for facilitating the adaptation of skeletal muscle and liver to a program of strenuous exercise, comprising: an amino acid mixture consisting essentially of 0.7 to 1.8 weight percent carnitine, 1.8 to 3.4 weight percent glutamine, 23.2 to 31.2 weight percent isoleucine, 50.7 to 32.4 weight percent leucine and 23.6 to 31.2 weight percent valine.
Claim 11
Dependent Claim 25 words
A composition as set forth in claim 8, further comprising: one or more proteins selected from the group consisting of casein, soy protein and lactalbumin.
Claim 12
Dependent Claim 32 words
A composition as set forth in claim 9, further comprising: the isoleucine, leucine and valine in said amino acid mixture being from 50 to 125 grams per 100 grams of said protein.
Claim 13
Dependent Claim 28 words
A composition as set forth in claim 9, further comprising: the carnitine in said amino acid mixture being from 0.3 to 2.0 per 100 grams of said protein.
Claim 14
Dependent Claim 29 words
A composition as set forth in claim 9, further comprising: the glutamine in said amino acid mixture being from 10.0 to 30.0 grams per 100 grams of said protein.
Claim 15
Dependent Claim 23 words
A composition as set forth in claim 8, further comprising: said amino acid mixture consisting essentially of L-carnitine, L-glutamine, L-isoleucine, L-leucine and L-valine.
Claim 16
Dependent Claim 24 words
A composition as set forth in claim 8, further comprising: one or more carbohydrates selected from the group consisting of syrup solids and sucrose.
Claim 17
Dependent Claim 28 words
A composition as set forth in claim 8, further comprising: one or more fats selected from the group consisting of sunflower oil, soybean oil and a medium-chain triglyceride.
Claim 18
Dependent Claim 37 words
A composition as set forth in claim 8, further comprising: one or more vitamins selected from the group consisting of Vitamin C, Folic acid, Vitamin B1, Vitamin B2, Niacin, Vitamin B6, Biotin, Choline, Vitamin B12 and Pantothenate.
Claim 19
Dependent Claim 27 words
A composition as set forth in claim 8, further comprising: one or more minerals selected from the group consisting of Sodium, Magnesium, Potassium, Calcium, Phosphate and Chloride.
Claim 20
Dependent Claim 69 words
A composition adapted to be used as a diet supplement solution for facilitating the adaptation of skeletal muscle and liver to a program of strenuous exercise, comprising: an amino acid mixture adapted to be added to every 400 milliliters of water used to make the solution, the amino acid mixture consisting essentially of 0.025 grams L-carnitine, 0.5 grams L-glutamine, 0.625 grams L-isoleucine, 0.85 grams L-leucine and 0.625 grams L-valine.
Claim 21
Dependent Claim 69 words
A composition adapted to be used as a diet supplement solution for facilitating the adaptation of skeletal muscle and liver to a program of strenuous exercise, comprising: an amino acid mixture adapted to be added to every 400 milliliters of water used to make the solution, the amino acid mixture consisting essentially of 0.025 grams L-carnitine, 0.5 grams L-glutamine, 0.625 grams L-isoleucine, 0.85 grams L-leucine and 0.625 grams L-valine.
Claim 22
Dependent Claim 38 words
A composition as set forth in claim 18, further comprising: 2.5 grams of proteins adapted to be added to the water, the proteins being one or more selected from the group consisting of casein, soy protein and lactalbumin.
Claim 23
Dependent Claim 37 words
A composition as set forth in claim 18, further comprising: 25.0 grams of carbohydrates adapted to be added to the water, the carbohydrates being one or more selected from the group consisting of syrup solids and sucrose.
Claim 24
Dependent Claim 50 words
A composition as set forth in claim 18, further comprising: a fat mixture adapted to be added to the water, the fat mixture consisting essentially of 2.5 grams of a mixture of sunflower oil and soybean oil in a volumetric ratio of 1:1 and of 6.0 grams of medium-chain triglycerides.
Claim 25
Dependent Claim 69 words
A composition as set forth in claim 18, further comprising: a vitamin mixture adapted to be added to the water, the vitamin mixture consisting essentially of 6.0 mg. of Vitamin C, 35 microgram of Folic acid, 1.0 mg. Vitamin B1, 1.2 mg. Vitamin B2, 1.7 mg. of Niacin, 0.15 mg. Vitamin B6, 15 microgram of Biotin, 5.0 mg. of Choline, 1.0 microgram of Vitamin B12 and 0.2 mg. Pantothenate.
Claim 26
Dependent Claim 51 words
A composition as set forth in claim 18, further comprising: a mineral mixture adapted to be added to the water, the mineral mixture consisting essentially of 60 mg. of Sodium, 20 mg. of Magnesium, 200 mg. of Potassium, 50 mg. of Calcium, 75 mg. of Phosphate and 350 mg. of Chloride.
Claim 27
Dependent Claim 205 words
A composition as set forth in claim 18, further comprising: 2.5 grams of proteins adapted to be added to the water, the proteins being one or more selected from the group consisting of casein, soy protein and lactalbumin: 25.0 grams of carbohydrates adapted to be added to the water, the carbohydrates being one or more selected from the group consisting of syrup solids and sucrose; a fat mixture adapted to be added to the water, the fat mixture consisting essentially of 2.5 grams of a mixture of sunflower oil and soybean oil in a volumetric ratio of 1:1 and of 6.0 grams of medium-chain triglycerides; a vitamin mixture adapted to be added to the water, the vitamin mixture consisting essentially of 6.0 mg. of Vitamin C, 35 microgram of Folic acid, 1.0 mg. Vitamin B1, 1.2 mg. Vitamin B2, 1.7 mg. of Niacin, 0.15 mg. Vitamin B6, 15 microgram of Biotin, 5.0 mg. of Choline, 1.0 microgram of Vitamin B12 and 0.2 mg. Pantothenate; a mineral mixture adapted to be added to the water, the minerals mixture consisting essentially of 60 mg. of Sodium, 20 mg. of Magnesium, 200 mg. of Potassium, 50 mg. of Calcium, 75 mg. of Phosphate and 350 mg. of Chloride.

References Cited (Backward Citations)

US3832465A Cited
US3950529A Cited
US4438144A Cited
US4357343A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1990-08-17 1991-02-16 1991-08-18 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1994-08-17 1995-02-16 1995-08-18 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1998-08-17 1999-02-16 1999-08-18 $7700.00 Window Closed / Lapsed

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