1,2,8,8A-tetrahydrocyclopropa(c)pyrrolo(3,2-e)-indol-4-(5H)-ones and related compounds

Claim 1

A compound selected from the group consisting of wherein R 1 is CH 3 --, --CH 2 Ph, CH 2 ═CHCH 2 --, --CH 2 SCH 3 , --CH 2 OCH 3 , --CH 2 OCH 2 CH 2 O-- CH 3 , --CH 2 CCl 3 , --CH 2 CH 2 Si(R 2 ) 3 , or H, where Ph is phenyl; R 2 is alkyl(C 1 -C 5 ), phenyl, or H; R 2 ' is alkyl(C 1 -C 5 ), phenyl, or H; R 3 is alkyl(C 1 -C 5 ), phenyl, or H; X is Cl, Br, or I; or OSO 2 R 40 where R 40 is alkyl(C 1 -C 5 ), phenyl, tolyl, bromophenyl, nitrophenyl, or trifluoromethyl; R 50 is hydrogen or the same as R 5 ; R 5 is a carbonyl acyl group selected from the group consisting of (vii) ##STR48## where n 2 is 0-3; and R 8 is H, CH 3 or C 2 H 5 ; (Viii) ##STR49## where X 5 is H, OH, OCH 3 , --NO 2 , --NH 2 , ##STR50## --NH--CN and R 8 has the meaning defined above; (ix) ##STR51## where n 3 is 1, 2, or 3; and R 8 , R 5 and X 5 have the meanings defined above; (x) ##STR52## where X 6 is H, NO 2 , NH 2 , ##STR53## (xi) ##STR54## where R 9 is CH 3 or NH 2 (xii) ##STR55## where R 8 and R 9 have the meanings defined above; (xiii) ##STR56## (xvii) ##STR57## where X 8 is --O--, --S--, NH; X 9 is --CH-- and X 5 has the meaning defined above; (xxii) ##STR58## where X 6 and R 8 have the meanings defined above; (xxiii) ##STR59## and when either of X 5 or X 6 is --OH or --NH 2 , then each of the above R 5 groups may be coupled with other groups to denote the following structures: ##STR60##