US4423228A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Process for preparing N-(methyl-sulfonyl)-1,2,8,8a-cyclopropa[c]benzo[1,2-b:4,3-b']dipyrrol-4(5H)-one
Assignee: Pharmacia and Upjohn Co
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Filing: 1982-02-08
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Granted: 1983-12-27
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Expires: 2002-02-08
Abstract
Abstract Novel antibacterially-active compound, 1,2,8,8a-cyclopropa[c]benzo[1,2-b:-4,3-b']dipyrol-4(5H)-one, prepared by a novel chemical process. This compound, as well as antibacterially-active intermediates, can be used to eradicate or control susceptible bacteria, for example, B. subtilis, K. pneumonia, S. lutea, S. aureus, and M. avium. Included is a process for the preparation of an intermediate compound of the formula ##STR1##
Inventors
- 👤 Wendell Wierenga
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-30 01:32
CPC Classifications
C; C07; C07D; C07D487/00; C07D487/02; C07D487/06; C07D209/00; C07D209/02; C07D209/04; C07D209/10; C07D209/12
Claims Analysis
Total Claims: 2
Claim 1
Independent Claim
57 words
A process for preparing a compound of the formula which comprises reacting a compound of the formula ##STR3## with triphenylphosphine/carbon tetrahalide, concentrating the reaction mixture in vacuo to a concentrate, applying said concentrate to a thick-layer silica gel plate, and eluting the desired compound therefrom with a non-polar organic solvent in which the desired compound is soluble.
Claim 2
Dependent Claim
57 words
A process for preparing a compound of the formula which comprises reacting a compound of the formula ##STR3## with triphenylphosphine/carbon tetrahalide, concentrating the reaction mixture in vacuo to a concentrate, applying said concentrate to a thick-layer silica gel plate, and eluting the desired compound therefrom with a non-polar organic solvent in which the desired compound is soluble.
References Cited (Backward Citations)
US4169888A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1986-12-26 | 1987-06-27 | 1987-12-27 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1990-12-26 | 1991-06-27 | 1991-12-27 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1994-12-26 | 1995-06-27 | 1995-12-27 | $7700.00 | Window Closed / Lapsed |