US4886669A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Galenical formulation
Assignee: Haleon CH SARL
•
Filing: 1987-11-25
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Granted: 1989-12-12
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Expires: 2007-11-25
Abstract
Abstract A water-dispersible tablet essentially consisting of (a) microparticles which contain at least one pharmaceutically active substance (b) a least one disintegrant and (c) a swellable material, which is able to generate a high viscosity when coming into contact with water; which disintegrates rapidly in water thus forming a homogeneous suspension of high viscosity that can easily be swallowed, is disclosed. It is prepared by methods known per se.
Inventors
- 👤 Kimon Ventouras
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-31 04:56
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/0087; A61K9/0095; A61K9/20; A61K9/2072; A61K9/2077; A61K9/2081
Claims Analysis
Total Claims: 21
Claim 1
Independent Claim
80 words
A water-dispersible tablet comprising (a) microparticles which contain at least one pharmaceutically active substance (b) at least one disintegrant and (c) a swellable material which is able to generate a high viscosity when coming into contact with water and which is selected from the group consisting of guar gum, xanthan gum, alginates, dextran, pectins, polysaccharides, sodium or calcium carboxymethylcellulose, hydroxypropylcellulose and hydroxypropylmethylcellulose; which tablet disintegrates rapidly in water forming a homogeneous suspension of high viscosity that can easily be swallowed.
Claim 2
Dependent Claim
80 words
A water-dispersible tablet comprising (a) microparticles which contain at least one pharmaceutically active substance (b) at least one disintegrant and (c) a swellable material which is able to generate a high viscosity when coming into contact with water and which is selected from the group consisting of guar gum, xanthan gum, alginates, dextran, pectins, polysaccharides, sodium or calcium carboxymethylcellulose, hydroxypropylcellulose and hydroxypropylmethylcellulose; which tablet disintegrates rapidly in water forming a homogeneous suspension of high viscosity that can easily be swallowed.
Claim 3
Dependent Claim
11 words
A water-dispersible tablet according to claim 1, which contains coated microparticles.
Claim 4
Dependent Claim
17 words
A water-dispersible tablet according to claim 2, which contains coated microparticles of 0.3 to 0.8 mm diameter.
Claim 5
Dependent Claim
15 words
A water-dispersible tablet according to claim 3, which contains guar gum as the swellable material.
Claim 6
Dependent Claim
16 words
A water-dispersible tablet according to claim 1, which contains granulated guar gum as the swellable material.
Claim 7
Dependent Claim
16 words
A water-dispersible tablet according to claim 4, which contains granulated guar gum as the swellable material.
Claim 8
Dependent Claim
13 words
A water-dispersible tablet according to claim 4, which contains crospovidone as the disintegrant.
Claim 9
Dependent Claim
13 words
A water-dispersible tablet according to claim 6, which contains crospovidone as the disintegrant.
Claim 10
Dependent Claim
14 words
A water-dispersible tablet according to claim 1, which disintegrates in water within one minute.
Claim 11
Dependent Claim
14 words
A water-dispersible tablet according to claim 4, which disintegrates in water within one minute.
Claim 12
Dependent Claim
14 words
A water-dispersible tablet according to claim 5, which disintegrates in water within one minute.
Claim 13
Dependent Claim
14 words
A water-dispersible tablet according to claim 8, which disintegrates in water within one minute.
Claim 14
Dependent Claim
26 words
A water-dispersible tablet according to claim 9, which forms, in water, a homogeneous suspension with an apparent viscosity at 20° C. of 30 to 1000 mPa.s.
Claim 15
Dependent Claim
26 words
A water-dispersible tablet according to claim 10, which forms, in water, a homogeneous suspension with an apparent viscosity at 20° C. of 30 to 1000 mPa.s.
Claim 16
Dependent Claim
26 words
A water-dispersible tablet according to claim 11, which forms, in water, a homogeneous suspension with an apparent viscosity at 20° C. of 30 to 1000 mPa.s.
Claim 17
Dependent Claim
26 words
A water-dispersible tablet according to claim 12, which forms, in water, a homogeneous suspension with an apparent viscosity at 20° C. of 30 to 1000 mPa.s.
Claim 18
Dependent Claim
82 words
A water-dispersible tablet according to claim 7, which contains as the pharmaceutically active substance(s) a member of the group consisting of drugs for the treatment of hypokaliaemia, psychotherapy drugs, non-steroidal antiinflammatory drugs, drugs for the therapy of hypocalcemic states or for calcium supplementation, drugs for the treatment of osteoporosis, muscle relaxants, antihistaminica, bronchodilators, drugs for the treatment of venous diseases, antitussive drugs, antipyretics, vitamins, cardiovascular and vascular drugs, geriatric drugs, pediatric drugs, drugs useful to balance the hydroelectrolytes, antibiotic drugs and nootropica.
Claim 19
Dependent Claim
82 words
A water-dispersible tablet according to claim 13, which contains as the pharmaceutically active substance(s) a member of the group consisting of drugs for the treatment of hypokaliaemia, psychotherapy drugs, non-steroidal antiinflammatory drugs, drugs for the therapy of hypocalcemic states or for calcium supplementation, drugs for the treatment of osteoporosis, muscle relaxants, antihistaminica, bronchodilators, drugs for the treatment of venous diseases, antitussive drugs, antipyretics, vitamins, cardiovascular and vascular drugs, geriatric drugs, pediatric drugs, drugs useful to balance the hydroelectrolytes, antibiotic drugs and nootropica.
Claim 20
Dependent Claim
82 words
A water-dispersible tablet according to claim 14, which contains as the pharmaceutically active substance(s) a member of the group consisting of drugs for the treatment of hypokaliaemia, psychotherapy drugs, non-steroidal antiinflammatory drugs, drugs for the therapy of hypocalcemic states or for calcium supplementation, drugs for the treatment of osteoporosis, muscle relaxants, antihistaminica, bronchodilators, drugs for the treatment of venous diseases, antitussive drugs, antipyretics, vitamins, cardiovascular and vascular drugs, geriatric drugs, pediatric drugs, drugs useful to balance the hydroelectrolytes, antibiotic drugs and nootropica.
Claim 21
Dependent Claim
82 words
A water-dispersible tablet according to claim 15, which contains as the pharmaceutically active substance(s) a member of the group consisting of drugs for the treatment of hypokaliaemia, psychotherapy drugs, non-steroidal antiinflammatory drugs, drugs for the therapy of hypocalcemic states or for calcium supplementation, drugs for the treatment of osteoporosis, muscle relaxants, antihistaminica, bronchodilators, drugs for the treatment of venous diseases, antitussive drugs, antipyretics, vitamins, cardiovascular and vascular drugs, geriatric drugs, pediatric drugs, drugs useful to balance the hydroelectrolytes, antibiotic drugs and nootropica.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1992-12-11 | 1993-06-12 | 1993-12-12 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1996-12-11 | 1997-06-12 | 1997-12-12 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2000-12-11 | 2001-06-12 | 2001-12-12 | $7700.00 | Window Closed / Lapsed |