US4882150A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Drug delivery system
Assignee: Individual
•
Filing: 1989-05-01
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Granted: 1989-11-21
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Expires: 2009-05-01
Abstract
Abstract An ophthalmic drug delivery system is provided which includes at least one particle of bioerodible material, and a liquid or ointment carrier which includes ophthalmic drug to be delivered to the ocular area. A process of making the system and a method of treatment are also provided.
Inventors
- 👤 Herbert E. Kaufman
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-30 11:30
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/0012; A61K9/0048; A61K9/14; A61K9/16; A61K9/1605; A61K9/1629; A61K9/1658
Claims Analysis
Total Claims: 11
Claim 1
Independent Claim
65 words
Method of treating the eye, comprising: applying directly to the eye a suspension of at least one particle of bioerodable material including an opthalmic drug in one of a liquid carrier and an ointment carrier containing at least the same opthalmic drug as in said at least one particle of bioerodable material in the same chemical form and having a pH acceptable to the eye.
Claim 2
Dependent Claim
65 words
Method of treating the eye, comprising: applying directly to the eye a suspension of at least one particle of bioerodable material including an opthalmic drug in one of a liquid carrier and an ointment carrier containing at least the same opthalmic drug as in said at least one particle of bioerodable material in the same chemical form and having a pH acceptable to the eye.
Claim 3
Dependent Claim
23 words
A method as in claim 1, wherein said at least one particle additionally includes a different drug than said drug in said carrier.
Claim 4
Dependent Claim
24 words
A method as in claim 1, wherein said carrier additionally includes a different drug than said drug disposed in said at least one particle.
Claim 5
Dependent Claim
33 words
A method as in claim 1, including a plurality of said particles, at least a portion of said particles including drug in a different concentration than at least another portion of said particles.
Claim 6
Dependent Claim
31 words
A method as in claim 1, including a plurality of said particles, at least a portion of said particles including a different drug than at least another portion of said particles.
Claim 7
Dependent Claim
42 words
A method as in claim 1, wherein a specific equilibrium between drug in said at least one particle and drug in said carrier provides a specific amount of drug to be delivered over a specific duration when administered to the ocular area.
Claim 8
Dependent Claim
31 words
A method as in claim 1, wherein said bioerodable material is at least one member selected from the group consisting of collagen, gelatin, polyvinyl alcohol, polymerized methycellulose and methyl cellulose derivatives.
Claim 9
Dependent Claim
39 words
A method as in claim 1, wherein said opthalmic drug is at least one member selected from the group consisting of idoxuridine, phenylephrine, pilocarpine and its acceptable salts, eserin, carachol, phospholine iodine, demecarium bromide, cyclopentolate, homatropine, scopolamine and epinephrine.
Claim 10
Dependent Claim
36 words
A method as in claim 1, wherein said opthalmic drug is at least one opthalmic steroid selected from the group consisting of hydrocortisone, hydrocortisone acetate, dexamethasone, dexamethasone 21-phosphate, fluocinolone, medrysone, prednisolone acetate, fluorometholone, betamethasone and triamcinoline.
Claim 11
Dependent Claim
37 words
A method as in claim 1, wherein said opthalmic drug is at least one antibiotic selected from the group consisting of tetracycline, chlorotetracycline, bacitracin, neomycin, polymyxin, granicidin, oxytetracycline, chloramphenicol, gentamycin, penicillin, erythromycin, tobry mycin, ciprofloxacin and norfloxacin.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1992-11-20 | 1993-05-22 | 1993-11-21 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1996-11-20 | 1997-05-22 | 1997-11-21 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2000-11-20 | 2001-05-22 | 2001-11-21 | $7700.00 | Window Closed / Lapsed |