US4861760A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Ophthalmological composition of the type which undergoes liquid-gel phase transition
Assignee: CHIBRET INTERNATIONAL SA
•
Filing: 1986-09-25
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Granted: 1989-08-29
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Expires: 2006-09-25
Abstract
Abstract The present invention relates to a pharmaceutical composition intended for contacting with a physiological liquid characterized in that said composition is intended to be administered as a non-gelled liquid form and is intended to gel in situ, this composition containing at least one polysaccharide in aqueous solution, of the type which undergoes liquid-gel phase transition gelling in situ under the effect of an increase in the ionic strength of said physiological liquid.
Inventors
- 👤 Claude Mazuel
- 👤 Marie-Claire Friteyre
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-01 06:31
CPC Classifications
A; A61; A61K; A61K9/00; C; C12; C12P; C12P19/00; C12P19/04; A61K47/00; A61K47/30; A61K47/36; A61K9/0012; A61K9/0048
Claims Analysis
Total Claims: 9
Claim 1
Independent Claim
38 words
A liquid aqueous ophthalmological composition comprising 0.1 to 2% by weight of gellan gum which on administration to the eye changes from a liquid to a gel as a result of the ionic strength of the lacrimal fluid.
Claim 2
Dependent Claim
38 words
A liquid aqueous ophthalmological composition comprising 0.1 to 2% by weight of gellan gum which on administration to the eye changes from a liquid to a gel as a result of the ionic strength of the lacrimal fluid.
Claim 3
Dependent Claim
19 words
The composition of claim 2 which additionally comprises about 0.001% to 5% by weight of an ophthalmic pharmaceutically-active substance.
Claim 4
Dependent Claim
23 words
The composition of claim 2 wherein the pharmaceutically-active substance is selected from the group consisting of an antibacterial substance and an anti-glaucoma drug.
Claim 5
Dependent Claim
23 words
The composition of claim 3 wherein the antibacterial substance is norfloxacin and the antiglaucoma drug is timolol maleate or a carbonic anhydrase inhibitor.
Claim 6
Dependent Claim
11 words
The composition of claim 1 wherein the gellan gum is Gelrite.
Claim 7
Dependent Claim
19 words
The composition of claim 5 which additionally comprises about 0.001% to 5% by weight of an ophthalmic pharmaceutically-active substance.
Claim 8
Dependent Claim
23 words
The composition of claim 6 wherein the pharmaceutically-active substance is selected from the group consisting of an antibacterial substance and an antiglaucoma drug.
Claim 9
Dependent Claim
29 words
The composition of claim 7 wherein the antibacterial substance is norfloxacin and the antiglaucoma drug is selected from the group consisting of timolol maleate and a carbonic anhydrase inhibitor.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1992-08-28 | 1993-02-27 | 1993-08-29 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1996-08-28 | 1997-02-27 | 1997-08-29 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2000-08-28 | 2001-02-27 | 2001-08-29 | $7700.00 | Window Closed / Lapsed |