US4829056A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Buccal tablet comprising etorphine or a salt thereof
Assignee: Reckitt Benckiser Healthcare UK Ltd
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Filing: 1987-04-10
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Granted: 1989-05-09
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Expires: 2007-04-10
Abstract
Abstract Pharmaceutical compositions in the form of a buccal tablet comprising etorphine or a salt thereof, at least one monosaccharide, disaccharide or a mixture thereof, and a mixture of xanthan gum and locust bean gum in a weight ratio 3:1 to 1:1, wherein the total weight of the mono- and/or di-saccharides relative to the combined weight of the xanthan and locust bean gums is in the ratio of 20:1 to 3:1. The tablet affords improved bioavailability.
Inventors
- 👤 Keith Sugden
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-08 20:58
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/0012; A61K9/0053; A61K9/006; A61K31/00; A61K31/33; A61K31/395; A61K31/435; A61K31/47; A61K31/485; A61K9/20; A61K9/2004; A61K9/2013; A61K9/2018; A61K9/2022; A61K9/205
Claims Analysis
Total Claims: 11
Claim 1
Independent Claim
64 words
A buccal tablet comprising etorphine or a salt thereof, at least one monosaccharide, disaccharide or a mixture thereof, and a mixture of xanthan gum and locust bean gum in a weight ratio 3:1 to 1:1, wherein the total weight of the mono- and/or di-saccharides relative to the combined weight of the xanthan and locust bean gums is in the ratio of 20:1 to 3:1.
Claim 2
Dependent Claim
64 words
A buccal tablet comprising etorphine or a salt thereof, at least one monosaccharide, disaccharide or a mixture thereof, and a mixture of xanthan gum and locust bean gum in a weight ratio 3:1 to 1:1, wherein the total weight of the mono- and/or di-saccharides relative to the combined weight of the xanthan and locust bean gums is in the ratio of 20:1 to 3:1.
Claim 3
Dependent Claim
37 words
A buccal tablet as claimed in claim 1 wherein the total weight of the mono- and/or di-saccharides relative to the combined weight of the xanthan and locust bean gums is in the ratio of 12:1 to 5:1.
Claim 4
Dependent Claim
19 words
A buccal tablet as claimed in claim 1 wherein the weight of etorphine is between 50 and 200 μg.
Claim 5
Dependent Claim
19 words
A buccal tablet as claimed in claim 1, wherein the monosaccharide is glucose, galactose, fructose, mannose, mannitol or sorbitol.
Claim 6
Dependent Claim
16 words
A buccal tablet as claimed in claim 1, wherein the disaccharide is maltose, lactose or sucrose.
Claim 7
Dependent Claim
19 words
A buccal tablet as claimed in claim 2, wherein the weight of etorphine is between 50 and 200 μg.
Claim 8
Dependent Claim
19 words
A buccal tablet as claimed in claim 2, wherein the monosaccharide is glucose, galactose, fructose, mannose, mannitol or sorbitol.
Claim 9
Dependent Claim
19 words
A buccal tablet as claimed in claim 3, wherein the monosaccharide is glucose, galactose, fructose, mannose, mannitol or sorbitol.
Claim 10
Dependent Claim
16 words
A buccal tablet as claimed in claim 2, wherein the disaccharide is maltose, lactose or sucrose.
Claim 11
Dependent Claim
16 words
A buccal tablet as claimed in claim 3, wherein the disaccharide is maltose, lactose or sucrose.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1992-05-08 | 1992-11-07 | 1993-05-09 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1996-05-08 | 1996-11-07 | 1997-05-09 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2000-05-08 | 2000-11-07 | 2001-05-09 | $7700.00 | Window Closed / Lapsed |