US4315936A
Expired / Lapsed
US
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Analgesic composition
Assignee: Ortho Pharmaceutical Corp
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Filing: 1979-12-17
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Granted: 1982-02-16
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Expires: 1999-12-17
Abstract
Abstract An analgesic composition comprising a mixture of a centrally-acting analgesic compound and α-methyl-4-[2-thienylcarbonyl] benzene acetic acid is described. Enhancement of the analgesic effect is observed in the combination.
Inventors
- 👤 Robert J. Capetola
- 👤 John L. McGuire
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-30 02:01
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/33; A61K31/395; A61K31/435; A61K31/47; A61K31/485; A61P; A61P25/00; A61P25/04
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
51 words
A method of controlling pain in mammals which comprises administering to a mammal an effective amount of a composition comprising from about 10 to 600 mg. of α-methyl-4-[2-thienylcarbonyl] benzene acetic acid and from about 5 to 80 mg. of a centrally-acting analgesic selected from the group consisting of codeine and butorphanol.
Claim 2
Independent Claim
51 words
A method of controlling pain in mammals which comprises administering to a mammal an effective amount of a composition comprising from about 10 to 600 mg. of α-methyl-4-[2-thienylcarbonyl] benzene acetic acid and from about 5 to 80 mg. of a centrally-acting analgesic selected from the group consisting of codeine and butorphanol.
Claim 3
Dependent Claim
11 words
The method of claim 1 wherein the centrally-active analgesic is codeine.
Claim 4
Dependent Claim
46 words
A composition useful in controlling pain in mammals comprising in combination from about 5 to 80 mg. of a centrally-acting analgesic selected from the group consisting of codeine and butorphanol from about 10 to 600 mg of α-methyl-4-[2-thienylcarbonyl] benzene acetic acid and a pharmaceutically acceptable carrier.
Claim 5
Dependent Claim
46 words
A composition useful in controlling pain in mammals comprising in combination from about 5 to 80 mg. of a centrally-acting analgesic selected from the group consisting of codeine and butorphanol from about 10 to 600 mg of α-methyl-4-[2-thienylcarbonyl] benzene acetic acid and a pharmaceutically acceptable carrier.
Claim 6
Dependent Claim
11 words
The composition of claim 3 wherein the centrally-acting analgesic is codeine.
Claim 7
Dependent Claim
11 words
The method of claim 1 wherein the centrally-acting analgesic is butorphanol.
Claim 8
Dependent Claim
11 words
The composition of claim 3 wherein the centrally-acting analgesic is butorphanol.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1985-02-15 | 1985-08-17 | 1986-02-16 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1989-02-15 | 1989-08-17 | 1990-02-16 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1993-02-15 | 1993-08-17 | 1994-02-16 | $7700.00 | Window Closed / Lapsed |