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US4817632A Expired / Lapsed US ⏱️ 0.0 years remaining

Oral fluid collection article

Assignee: Silicon Valley Bank Inc
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Filing: 1987-06-23
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Granted: 1989-04-04
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Expires: 2007-06-23
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Abstract

Abstract The present invention is an oral fluid collection article for placement in the buccal cavity of an individual for the collection and fittering of a saliva fluid. The collection article has a semi-permable membrane container enclosing an osmotic substance means.

Inventors

  • 👤 Willfried Schramm

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-24 18:56
CPC Classifications
A; A61; A61B; A61B5/00; A61B5/42; A61B5/4261; A61B5/4277; A61B10/00; A61B10/0045; A61B10/0051; A61F; A61F13/00; A61F13/15; A61F13/20; A61F13/2002; A61F13/2008; A61F13/2051; A61F13/2071

Claims Analysis

Total Claims: 14
Claim 1
Independent Claim 125 words
An oral fluid collection article for placement entirely in the buccal cavity of an individual for collection and filtering of a saliva fluid sample comprising: a semi-permeable membrane container defining an enclosed chamber, said semi-permeable membrane container having pores which are of a size to allow desirable oral fluid molecules to pass through, said pores acting as a filter for filtering out of larger undesirable particulate or molecular matter from said saliva; and osmotic substance means being disposed in said enclosed chamber for creating an osmotic pressure system inside of said chamber and for drawing oral fluid from said buccal cavity through said container and into said chamber of said semi-permeable membrane container and retaining at least a portion of said fluid in said chamber.
Claim 2
Dependent Claim 125 words
An oral fluid collection article for placement entirely in the buccal cavity of an individual for collection and filtering of a saliva fluid sample comprising: a semi-permeable membrane container defining an enclosed chamber, said semi-permeable membrane container having pores which are of a size to allow desirable oral fluid molecules to pass through, said pores acting as a filter for filtering out of larger undesirable particulate or molecular matter from said saliva; and osmotic substance means being disposed in said enclosed chamber for creating an osmotic pressure system inside of said chamber and for drawing oral fluid from said buccal cavity through said container and into said chamber of said semi-permeable membrane container and retaining at least a portion of said fluid in said chamber.
Claim 3
Dependent Claim 32 words
The oral fluid collection article of claim 1 wherein said osmotic substance means comprises a crystalline material which is soluble in saliva and will allow interference free analysis of the saliva sample.
Claim 4
Dependent Claim 30 words
The oral fluid collection article of claim 1 wherein said osmotic substance means comprises an amorphous material which accommodates water and will allow interference free analysis of the saliva sample.
Claim 5
Dependent Claim 25 words
The oral fluid collection article of claim 1 wherein said osmotic substance means comprises a high-molarity solution of a crystalline material being dissolved in water.
Claim 6
Dependent Claim 26 words
The oral fluid collection article of claim 1 wherein said osmotic substance means comprise a high molarity solution of an amorphous material being dissolved in water.
Claim 7
Dependent Claim 21 words
The oral fluid collection article of claim 1 wherein said osmotic substance means is a carbohydrate having a low molecular weight.
Claim 8
Dependent Claim 24 words
The oral fluid collection article of claim 1 wherein said osmotic substance means is taken from the group consisting of glucose, fructose and sucrose.
Claim 9
Dependent Claim 21 words
The oral fluid collection article of claim 1 wherein said osmotic substance means consists of a nontoxic polymer soluble in water.
Claim 10
Dependent Claim 21 words
The oral fluid collection article of claim 1 wherein in said osmotic substance consists of a nontoxic material which accommodates water.
Claim 11
Dependent Claim 29 words
The oral fluid collection article of claim 1 wherein said pores are of a size which will filter out particles having a size of about 25,000 daltons or greater.
Claim 12
Dependent Claim 25 words
The oral fluid collection article of claim 1 wherein said pores are of a size which allows osmotic pressure to be created in said chamber.
Claim 13
Dependent Claim 50 words
The oral fluid collection article of claim 1 further comprising: an outer protective membrane for containing and protecting said semi-permeable membrane container, said outer protective membrane being disposed about and enclosing said semi-permeable membrane container, said outer protective membrane having macroscopic pores for allowing said oral fluid to pass therethrough.
Claim 14
Dependent Claim 20 words
The oral fluid collection article of claim 12 wherein said outer protective membrane container is made of a non-toxic material.

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1992-04-03 1992-10-03 1993-04-04 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1996-04-03 1996-10-03 1997-04-04 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2000-04-03 2000-10-03 2001-04-04 $7700.00 Window Closed / Lapsed

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