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US4806484A Expired / Lapsed US ⏱️ 0.0 years remaining

Perfusion airlift bioreactor

Assignee: IGB PRODUCTS Ltd 14310 CATALINA ST SAN LEANDRO CA 94577 A CORP OF
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Filing: 1987-08-07
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Granted: 1989-02-21
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Expires: 2007-08-07
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Abstract

Abstract A perfusion airlift bioreactor system that consists of the bioreactor, a media reservoir and a molecular weight cutoff (MWCO) filter positioned between the media reservoir and the airlift bioreactor.

Inventors

  • 👤 Ashot Petrossian
  • 👤 Andy DeGiovanni

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-04 19:48
CPC Classifications
C; C12; C12M; C12M25/00; C12M25/16; C12M29/00; C12M29/02; C12M29/06; C12M29/08; C12M29/10; C12M47/00; C12M47/10

Claims Analysis

Total Claims: 2
Claim 1
Independent Claim 151 words
An apparatus for growing eukaryotic cells consisting essentially of: (a) a two liter airlift bioreactor accomaditing eukaryotic cells in suspension, encapsulated or on microcarriers in a medium supporting cell growth, (b) a 19 square foot 30,000 molecular weight cutoff hollow fiber bundle filter, positioned between said bioreactor and said media reservoir, (c) pump means operably connected to said bioreactor and said filter for circulating said medium into the filter and returning said medium to the bioreactor, (d) pump means operably connected to said filter and a 50 liter medium reservoir for circulating said medium from said reservoir to said filter and returning said medium to said medium reservoir, (e) pump means operably connected to said bioreactor for admitting air into said airlift bioreactor for stirring the suspension of cells and medium whereby, (f) the spent bioreactor medium containing product/s is dialyzed aganst a fresh reservoir medium through said hollow fiber filter.
Claim 2
Independent Claim 151 words
An apparatus for growing eukaryotic cells consisting essentially of: (a) a two liter airlift bioreactor accomaditing eukaryotic cells in suspension, encapsulated or on microcarriers in a medium supporting cell growth, (b) a 19 square foot 30,000 molecular weight cutoff hollow fiber bundle filter, positioned between said bioreactor and said media reservoir, (c) pump means operably connected to said bioreactor and said filter for circulating said medium into the filter and returning said medium to the bioreactor, (d) pump means operably connected to said filter and a 50 liter medium reservoir for circulating said medium from said reservoir to said filter and returning said medium to said medium reservoir, (e) pump means operably connected to said bioreactor for admitting air into said airlift bioreactor for stirring the suspension of cells and medium whereby, (f) the spent bioreactor medium containing product/s is dialyzed aganst a fresh reservoir medium through said hollow fiber filter.

References Cited (Backward Citations)

US3186917A Cited
US3418208A Cited
US4545945A Cited
EP0112812A2 Cited
EP0148764A2 Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1992-02-21 1992-08-22 1993-02-21 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1996-02-21 1996-08-22 1997-02-21 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2000-02-21 2000-08-22 2001-02-21 $7700.00 Window Closed / Lapsed

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