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US4786595A
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Analytical element for analysis of an analyte
Assignee: Fujifilm Holdings Corp
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Filing: 1986-04-29
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Granted: 1988-11-22
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Expires: 2006-04-29
Abstract
Abstract An analytical element for quantitative analysis of analyte contained in a body fluid or the like, which has at least one reagent layer comprising a reactive reagent and a binder, characterized in that a portion or whole of the binder is a polycarboxylic acid carrying a nonionic surface active agent attached through ester linkage to at least a portion of the carboxyl groups contained therein.
Inventors
- 👤 Fuminori Arai
- 👤 Takushi Miyazako
- 👤 Harumi Katsuyama
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-02 07:45
CPC Classifications
C; C12; C12Q; C12Q1/00; C12Q1/26; C12Q1/34; C12Q1/40; C12Q1/60; G; G01; G01N; G01N31/00; G01N31/22; G01N33/00; G01N33/48; G01N33/50; G01N33/52; G01N33/525; Y; Y10; Y10S; Y10S436/00; Y10S436/805
Claims Analysis
Total Claims: 10
Claim 1
Independent Claim
91 words
An analytical element having at least one reagent layer comprising a color-forming reagent which forms a color in the presence of an analyte and a hydrophilic binder wherein a portion or all of the binder is a polymer or copolymer containing a repeating unit represented by the formula ##STR3## wherein at least a portion of the carboxyl groups in the repeating unit represented by formula (I), have a nonionic group containing a repeating unit represented by formula (II) attached to the carboxyl group through an ester linkage: --CH.sub.2 CH.sub.2 O-- (II).
Claim 2
Dependent Claim
91 words
An analytical element having at least one reagent layer comprising a color-forming reagent which forms a color in the presence of an analyte and a hydrophilic binder wherein a portion or all of the binder is a polymer or copolymer containing a repeating unit represented by the formula ##STR3## wherein at least a portion of the carboxyl groups in the repeating unit represented by formula (I), have a nonionic group containing a repeating unit represented by formula (II) attached to the carboxyl group through an ester linkage: --CH.sub.2 CH.sub.2 O-- (II).
Claim 3
Dependent Claim
83 words
The analytical element as claimed in claim 1, in which said nonionic group has the formula (III): R--CH.sub.2 CH.sub.2 O--.sub.n H (III) in which R is an alkyl group having 2-22 carbon atoms, an aryl group containing substituent of an alkyl group of 4-12 carbon atoms, an alkylcarbonyloxy group containing an alkyl group of 9-19 carbon atoms, or a sorbitane or sorbitol residue having a hydroxyl group esterified with a carboxylic acid of 2-22 carbon atoms; and n is an integer from 2-40.
Claim 4
Dependent Claim
41 words
The analytical element as claimed in claim 1, in which said color-forming reagent comprises oxidoreductase and a color-forming compound capable of forming a dye under the action of a reaction product produced by reaction of an introduced analyte and the oxidoreductase.
Claim 5
Dependent Claim
41 words
The analytical element as claimed in claim 1 which is in the form of a multilayer analytical element for quantitative analysis of an analyte, comprising in this order, a spreading layer, a reagent layer and a transparent support which are superposed.
Claim 6
Dependent Claim
19 words
The analytical element as claimed in claim 4, in which said analyte is glucose, cholesterol, triglyceride or uric acid.
Claim 7
Dependent Claim
14 words
The analytical element as claimed in claim 4, in which said analyte is amylase.
Claim 8
Dependent Claim
56 words
The analytical element as claimed in claim 1 in which said copolymer contains said repeating unit of formula (I) and a monomer unit selected from the group consisting of methyl acrylate, ethyl acrylate, propyl acrylate, butyl acrylate, pentyl acrylate, hydroxyethyl acrylate, methyl vinyl ether, ethyl vinyl ether, propyl vinyl ether, butyl vinyl ether, styrene, and p-hydroxystyrene.
Claim 9
Dependent Claim
96 words
A multilayer analytical element for analysis of amylase comprising a diazonium color-forming layer containing a diazonium compound and a binder, and a coupler substrate layer provided on the diazonium color-forming layer, in which at least a portion or all of said binder is a polymer containing a repeating unit represented by formula (I) ##STR4## wherein at least a portion of the carboxyl groups in the repeating unit represented by formula (I), have a nonionic group containing a repeating unit represented by formula (II) attached to the carboxyl group through an ester linkage: --CH.sub.2 CH.sub.2 O-- (II).
Claim 10
Dependent Claim
96 words
A multilayer analytical element for analysis of amylase comprising a diazonium color-forming layer containing a diazonium compound and a binder, and a coupler substrate layer provided on the diazonium color-forming layer, in which at least a portion or all of said binder is a polymer containing a repeating unit represented by formula (I) ##STR4## wherein at least a portion of the carboxyl groups in the repeating unit represented by formula (I), have a nonionic group containing a repeating unit represented by formula (II) attached to the carboxyl group through an ester linkage: --CH.sub.2 CH.sub.2 O-- (II).
References Cited (Backward Citations)
US3616229A
Cited
US3715325A
Cited
US3953295A
Cited
US4050898A
Cited
US4144306A
Cited
US4258001A
Cited
US4430436A
Cited
US4486537A
Cited
JPS59300A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1991-11-22 | 1992-05-23 | 1992-11-22 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1995-11-22 | 1996-05-23 | 1996-11-22 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1999-11-22 | 2000-05-23 | 2000-11-22 | $7700.00 | Window Closed / Lapsed |