Patent US4786492A successfully refreshed from Google Patents.
US4786492A
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Method and composition for prevention and treatment of oral disease
Assignee: Micropure Inc
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Filing: 1987-07-22
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Granted: 1988-11-22
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Expires: 2007-07-22
Abstract
Abstract The use of stabilized chlorine dioxide as a composition for the treatment and prevention of oral disease and the reduction of oral malodor is disclosed. Chlorine dioxide is an effective anti-plaque agent, anti-gingivitis and anti-periodontitis agent, and also effective to destroy malodorous sulfur compounds. Preferred concentrations are in the range of 0.005% to 2% and the chlorine dioxide may be in the form of a wash or rinse in solution, a soak or as a toothpaste.
Inventors
- 👤 Perry A. Ratcliff
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-07 10:36
CPC Classifications
C; C11; C11D; C11D7/00; C11D7/02; A; A01; A01N; A01N59/00; A61; A61K; A61K33/00; A61K33/20; A61K8/00; A61K8/18; A61K8/19; A61K8/22; A61L; A61L12/00; A61L12/08; A61L12/10; A61L12/102; A61Q; A61Q11/00; A61Q11/02; C11D3/00; C11D3/0005; C11D3/0078
Claims Analysis
Total Claims: 7
Claim 1
Independent Claim
66 words
A method for reducing dental plaque, said method comprising the step of retarding degradation of sucrose into glucose or fructose by killing and by reducing the number of streptococcus mutans to a more than 90% level through topical application within the oral cavity for a period of ten seconds of a solution containing stabilized chlorine dioxide in a concentration in the range of 0.005% to 0.2%.
Claim 2
Independent Claim
66 words
A method for reducing dental plaque, said method comprising the step of retarding degradation of sucrose into glucose or fructose by killing and by reducing the number of streptococcus mutans to a more than 90% level through topical application within the oral cavity for a period of ten seconds of a solution containing stabilized chlorine dioxide in a concentration in the range of 0.005% to 0.2%.
Claim 3
Independent Claim
81 words
A method for reducing dental plaque by altering the milieu of the ecology of the bacteria within the oral cavity, said method comprising the steps of: (a) applying within the oral cavity for a period of ten seconds, a solution containing stabilized chlorine dioxide in a concentration of 0.005% to 0.2%; (b) retarding formation of dextrans and levans; and (c) interfering with the supply of nutrition to the bacteria; whereby, the milieu of the bacteria within the oral cavity is altered.
Claim 4
Independent Claim
81 words
A method for reducing dental plaque by altering the milieu of the ecology of the bacteria within the oral cavity, said method comprising the steps of: (a) applying within the oral cavity for a period of ten seconds, a solution containing stabilized chlorine dioxide in a concentration of 0.005% to 0.2%; (b) retarding formation of dextrans and levans; and (c) interfering with the supply of nutrition to the bacteria; whereby, the milieu of the bacteria within the oral cavity is altered.
Claim 5
Independent Claim
110 words
A method for reducing dental plaque by altering the milieu of the ecology of the bacteria within the oral cavity, said method comprising the steps of: (a) applying within the oral cavity for a period of ten seconds a solution containing stabilized chlorine dioxide in a concentration; in the range of 0.005% to 0.2%; (b) breaking down the double bonds in the glucosyltransferases present in the oral cavity; (c) preventing degradation of sucrose into glucose and fructose; and (d) preventing formulation of dextrans, glucans, lucans and fructans; whereby, the resulting interference with the supply of nutrition to the bacteria present within the oral cavity reduces the formation of dental plaque.
Claim 6
Independent Claim
110 words
A method for reducing dental plaque by altering the milieu of the ecology of the bacteria within the oral cavity, said method comprising the steps of: (a) applying within the oral cavity for a period of ten seconds a solution containing stabilized chlorine dioxide in a concentration; in the range of 0.005% to 0.2%; (b) breaking down the double bonds in the glucosyltransferases present in the oral cavity; (c) preventing degradation of sucrose into glucose and fructose; and (d) preventing formulation of dextrans, glucans, lucans and fructans; whereby, the resulting interference with the supply of nutrition to the bacteria present within the oral cavity reduces the formation of dental plaque.
Claim 7
Dependent Claim
31 words
The method as set forth in claim 2 wherein said step of retarding includes the step of killing and reducing the number of streptococcus mutans to a greater than 90% level.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1991-11-22 | 1992-05-23 | 1992-11-22 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1995-11-22 | 1996-05-23 | 1996-11-22 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1999-11-22 | 2000-05-23 | 2000-11-22 | $7700.00 | Window Closed / Lapsed |