US4758595A
Expired / Lapsed
US
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Disinfecting and preserving systems and methods of use
Assignee: Bausch and Lomb Inc
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Filing: 1986-05-14
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Granted: 1988-07-19
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Expires: 2006-05-14
Abstract
Abstract A preserving solution comprising a microbicidally or fungicidally effective amount of a biguanide or water-soluble salt thereof, in combination with a buffer system, said biguanide having the formula: <IMAGE> +TR <IMAGE> wherein n is from 1 to 500, said biguanide being present in an amount from 0.000001 to 0.0003 weight percent, useful for preserving, for example, a cosmetic formulation.
Inventors
- 👤 Lai Ogunbiyi
- 👤 Francis X. Smith
- 👤 Thomas M. Riedhammer
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-31 22:11
CPC Classifications
A; A61; A61Q; A61Q17/00; A61Q17/005; A01; A01N; A01N47/00; A01N47/40; A01N47/42; A01N47/44; A61K; A61K8/00; A61K8/18; A61K8/30; A61K8/40; A61K8/43; A61K8/72; A61K8/84; A61L; A61L12/00; A61L12/08; A61L12/14; A61L12/141; A61L12/142; C; C11; C11D; C11D3/00; C11D3/0005; C11D3/0078; C11D3/16; C11D3/37; C11D3/3703; C11D3/3723; C11D3/48; A61K2800/00; A61K2800/40; A61K2800/52; A61K2800/524
Claims Analysis
Total Claims: 19
Claim 1
Independent Claim
49 words
A solution comprising a microbicidally or fungicidally effective amount of a biguanide or water-soluble salt thereof, in combination with a borate buffer system, said biguanide having the formula: ##STR10## wherein n is from 1 to 500, said biguanide being present in an amount from 0.000001 to 0.0003 weight percent.
Claim 2
Dependent Claim
49 words
A solution comprising a microbicidally or fungicidally effective amount of a biguanide or water-soluble salt thereof, in combination with a borate buffer system, said biguanide having the formula: ##STR10## wherein n is from 1 to 500, said biguanide being present in an amount from 0.000001 to 0.0003 weight percent.
Claim 3
Dependent Claim
13 words
The solution of claim 1 wherein the biguanide is a polymeric water-soluble salt.
Claim 4
Dependent Claim
15 words
The solution of claim 2 wherein the biguanide is a water-soluble salt of polyhexamethylene biguanide.
Claim 5
Dependent Claim
12 words
The solution of claim 1 wherein the biguanide is a water-soluble monomer.
Claim 6
Dependent Claim
16 words
The solution of claim 2 wherein the biguanide is a polymer having molecular weights under 100,000.
Claim 7
Dependent Claim
21 words
The solution of claim 5 wherein the biguanide is a polymer having molecular weights in the range from 1,000 to 50,000.
Claim 8
Dependent Claim
16 words
The solution of claim 5 wherein n of the biguanide polymer averages between 2 and 12.
Claim 9
Dependent Claim
12 words
The solution of claim 3 wherein n averages from 4 to 7.
Claim 10
Dependent Claim
15 words
The solution of claim 3 containing at least 0.00001 weight percent of the biguanide polymer.
Claim 11
Dependent Claim
22 words
The solution of claim 9 wherein the biguanide polymer is present in an amount from about 0.0001 to about 0.0003 weight percent.
Claim 12
Dependent Claim
23 words
The solution of claim 1 containing microbicidally effective mixtures of a biguanide or water-soluble salt thereof and at least one other germicidal agent.
Claim 13
Dependent Claim
22 words
The solution of claim 2 wherein the biguanide is a water-soluble salt of polyhexamethylene biguanide wherein n averages between 2 and 12.
Claim 14
Dependent Claim
24 words
A solution according to claim 3 wherein the biguanide is effective to preserve the solution against S. aureus, P. aeruginosa and E. coli organisms.
Claim 15
Dependent Claim
20 words
A solution according to claim 3 which is effective as a disinfecting solution against S. epidermis and C. albicans organisms.
Claim 16
Dependent Claim
16 words
A solution according to claim 1 in which the biguanide is a preservative for the solution.
Claim 17
Dependent Claim
7 words
An aqueous solution according to claim 15.
Claim 18
Dependent Claim
42 words
A solution according to claim 15 in which the solution is an aqueous solution for contact lens care and contains additionally at least one component from the group consisting of amphoteric, nonionic and cationic surfactants, tonicity agents, sequestering agents and viscosity builders.
Claim 19
Dependent Claim
42 words
A solution according to claim 1 in which the solution is an aqueous solution for disinfecting contact lenses and contains additionally at least one component from the group consisting of amphoteric, nonionic and cationic surfactants, tonicity agents, sequestering agents and viscosity builders.
References Cited (Backward Citations)
US2336605A
Cited
US4022834A
Cited
GB1432345A
Cited
US3860729A
Cited
US4405645A
Cited
US4361548A
Cited
US4499077A
Cited
FR2517208A1
Cited
US4519803A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1991-07-19 | 1992-01-18 | 1992-07-19 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1995-07-19 | 1996-01-18 | 1996-07-19 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1999-07-19 | 2000-01-18 | 2000-07-19 | $7700.00 | Window Closed / Lapsed |