US4735945A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Method for inhibiting bone resorption and collagenase release
Assignee: Vipont Pharmaceutical Inc
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Filing: 1986-03-13
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Granted: 1988-04-05
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Expires: 2006-03-13
Abstract
Abstract Method of inhibiting bone resorption and collagenase release in mammalian periodontal subjects using a benzo-c-phenanthridine alkaloid compound.
Inventors
- 👤 Seizaburo Sakamoto
- 👤 Masako Sakamoto
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 12:52
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/33; A61K31/395; A61K31/435; A61K31/47
Claims Analysis
Total Claims: 6
Claim 1
Independent Claim
38 words
A method of inhibiting bone resorption and collagenase activity in mammals having periodontal disease, comprising adminstering to said mammals in amount from about 0.2 to about 20 umol/L of sanguinarine, sanguinarine pseudoethanolate or mixtures thereof dissolved in dimethylsulfoxide.
Claim 2
Independent Claim
38 words
A method of inhibiting bone resorption and collagenase activity in mammals having periodontal disease, comprising adminstering to said mammals in amount from about 0.2 to about 20 umol/L of sanguinarine, sanguinarine pseudoethanolate or mixtures thereof dissolved in dimethylsulfoxide.
Claim 3
Dependent Claim
19 words
The method of claim 1 wherein said sanguinarine is administered in amounts from about 1 to about 20 umol/L.
Claim 4
Dependent Claim
19 words
The method of claim 1 wherein sanguinarine pseudoethanolate is administered in amounts from about 0.2 to about 20 umol/L.
Claim 5
Dependent Claim
14 words
The method of claim 2 wherein sanguinarine is administered in amount of 20 umol/L.
Claim 6
Dependent Claim
15 words
The method of claim 4 wherein sanguinarine pseudoethanolate is administered in amounts of 5 umol/L.
References Cited (Backward Citations)
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1991-04-05 | 1991-10-05 | 1992-04-05 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1995-04-05 | 1995-10-05 | 1996-04-05 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1999-04-05 | 1999-10-05 | 2000-04-05 | $7700.00 | Window Closed / Lapsed |