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US4729959A
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Glucose reference control for glucose test strips
Assignee: Streck Inc
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Filing: 1986-02-24
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Granted: 1988-03-08
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Expires: 2006-02-24
Abstract
Abstract A stable glucose reference control has been found in which the true value and the measured value of glucose in blood, colorimetrically obtained with glucose test strips, is approximately the same. The glucose reference control comprises an aqueous suspension of: (i) 40 to 500 mg/dL of glucose, and (ii) about 0.1 to 0.3×10 12 /dL red blood cells fixed with a fixing agent to render the red blood cells incapable of metabolizing glucose.
Inventors
- 👤 Wayne L. Ryan
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-24 11:53
CPC Classifications
G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/96; C; C12; C12Q; C12Q1/00; C12Q1/54; G01N2496/00; G01N2496/05; Y; Y10; Y10T; Y10T436/00; Y10T436/10; Y10T436/101666; Y10T436/104998; Y10T436/107497; Y10T436/108331
Claims Analysis
Total Claims: 13
Claim 1
Independent Claim
84 words
A glucose reference control for glucose test strips consisting essentially of an aqueous suspension of: (i) about 40 to 500 mg/dL of glucose, and (ii) about 0.1 to 0.3×10 12 /dL red blood cells fixed with a fixing agent to render said red blood cells incapable of metabolizing glucose, the number of said fixed red blood cells being sufficient to provide a glucose reference control for glucose test strips in which the true value of glucose and the measured value is approximately the same.
Claim 2
Dependent Claim
84 words
A glucose reference control for glucose test strips consisting essentially of an aqueous suspension of: (i) about 40 to 500 mg/dL of glucose, and (ii) about 0.1 to 0.3×10 12 /dL red blood cells fixed with a fixing agent to render said red blood cells incapable of metabolizing glucose, the number of said fixed red blood cells being sufficient to provide a glucose reference control for glucose test strips in which the true value of glucose and the measured value is approximately the same.
Claim 3
Dependent Claim
15 words
A glucose reference control according to claim 1 wherein the fixing agent is an aldehyde.
Claim 4
Dependent Claim
12 words
glucose reference control according to claim 2 wherein the aldehyde is glutaraldehyde.
Claim 5
Dependent Claim
16 words
A glucose reference control according to claim 1 wherein the fixing agent is an imidinating agent.
Claim 6
Dependent Claim
14 words
A glucose reference control according to claim 4 wherein the imidinating agent is dimethylsuberimidate.
Claim 7
Dependent Claim
12 words
A glucose reference control according to claim 1 including a phosphate buffer.
Claim 8
Dependent Claim
15 words
A glucose reference control according to claim 6 wherein the phosphate buffer is sodium phosphate.
Claim 9
Dependent Claim
23 words
A glucose reference control according to claim 1 wherein the fixed human red blood cell concentration is about 0.2 to 0.3×10 12 /dL.
Claim 10
Dependent Claim
19 words
A glucose reference control according to claim 1 wherein the fixed red blood cell concentration is 0.3×0.10 12 /dL.
Claim 11
Dependent Claim
19 words
A glucose reference control according to claim 1 wherein the glucose content is about 60 mg to 250 mg/dl.
Claim 12
Dependent Claim
18 words
A glucose reference control according to claim 1 wherein the red blood cells are human red blood cells.
Claim 13
Dependent Claim
18 words
A glucose reference control according to claim 1 wherein the red blood cells are bovine red blood cells.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1991-03-08 | 1991-09-07 | 1992-03-08 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1995-03-08 | 1995-09-07 | 1996-03-08 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1999-03-08 | 1999-09-07 | 2000-03-08 | $7700.00 | Window Closed / Lapsed |