Patent US4698263A successfully refreshed from Google Patents.
US4698263A
Expired / Lapsed
US
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Sac having a marker linked thereto
Assignee: Becton Dickinson and Co
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Filing: 1985-05-23
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Granted: 1987-10-06
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Expires: 2005-05-23
Abstract
Abstract Vesicles are formed having a detectable marker and ligand conjugated to compounds forming the vesicle wall. The vesicles are dried, and reformed by addition of water for use in an assay.
Inventors
- 👤 Daniel B. Wagner
- 👤 Robert A. Baffi
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-08 09:23
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/10; A61K9/127; A61K9/1271; A61K49/00; A61K49/0002; A61K9/1277; Y; Y10; Y10S; Y10S436/00; Y10S436/829; Y10T; Y10T428/00; Y10T428/29; Y10T428/2982; Y10T428/2984
Claims Analysis
Total Claims: 10
Claim 1
Independent Claim
34 words
A composition comprising: a dry mixture of vesicle wall forming amphiphilic compounds, at least a portion of said compounds being a vesicle wall forming amphiphilic chelating agent, having a detectable metal atom complexed therewith.
Claim 2
Dependent Claim
34 words
A composition comprising: a dry mixture of vesicle wall forming amphiphilic compounds, at least a portion of said compounds being a vesicle wall forming amphiphilic chelating agent, having a detectable metal atom complexed therewith.
Claim 3
Dependent Claim
20 words
The composition of claim 1 wherein at least a portion of the wall forming compounds have a ligand conjugated thereto.
Claim 4
Dependent Claim
16 words
The composition of claim 1 wherein the dry mixture is produced by drying of a vesicle.
Claim 5
Dependent Claim
22 words
The composition of claim 1 wherein a further portion of said vesicle is formed from an amphiphilic compound derivatized with a ligand.
Claim 6
Dependent Claim
17 words
The composition of claim 4 wherein the detectable metal atoms are comprised of fluorescent rare earth metal.
Claim 7
Dependent Claim
20 words
The composition of claim 4 wherein the chelating portion of the amphiphilic chelating agent is comprised of a diethylenetriaminepentaacetic acid.
Claim 8
Dependent Claim
20 words
The composition of claim 6 wherein the hydrophobic portion of the amphiphilic chelating agent is comprised of a dialkyl amine.
Claim 9
Dependent Claim
17 words
The composition of claim 7 wherein the detectable metal atoms are comprised of fluorescent rare earth metal.
Claim 10
Dependent Claim
18 words
The composition of claim 6 wherein the hydrophobic portion of the amphiphilic chelating agent is comprised of cholesterol.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1990-10-05 | 1991-04-06 | 1991-10-06 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1994-10-05 | 1995-04-06 | 1995-10-06 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1998-10-05 | 1999-04-06 | 1999-10-06 | $7700.00 | Window Closed / Lapsed |