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US4664906A
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Oral compositions
Assignee: Johnson and Johnson Consumer Inc
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Filing: 1984-08-30
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Granted: 1987-05-12
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Expires: 2004-08-30
Abstract
Abstract Oral compositions which exhibit antimicrobial activity containing hexedine and a pharmaceutically acceptable zinc compound.
Inventors
- 👤 Tibor Sipos
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-26 12:21
CPC Classifications
A; A61; A61K; A61K8/00; A61K8/18; A61K8/30; A61K8/49; A61K8/494; A61K8/4946; A61K8/19; A61K8/27; A61Q; A61Q11/00
Claims Analysis
Total Claims: 9
Claim 1
Independent Claim
78 words
An oral composition comprising a pharmaceutically-acceptable vehicle containing from about 0.0025 to about 2.0% by weight of hexedine and from about 0.01 to about 25.0% by weight of a pharmaceutically-acceptable zinc salt selected from the group consisting of zinc chloride, zinc sulfate, zinc citrate, zinc acetate, zinc lactate, zinc salicylate, zinc thiocyanate, zinc gluconoheptanoate, zinc gluconate, zinc maleate, and zinc fumarate wherein the hexedine and zinc are present in a weight ratio of from about 1:1 to 1:32.
Claim 2
Dependent Claim
78 words
An oral composition comprising a pharmaceutically-acceptable vehicle containing from about 0.0025 to about 2.0% by weight of hexedine and from about 0.01 to about 25.0% by weight of a pharmaceutically-acceptable zinc salt selected from the group consisting of zinc chloride, zinc sulfate, zinc citrate, zinc acetate, zinc lactate, zinc salicylate, zinc thiocyanate, zinc gluconoheptanoate, zinc gluconate, zinc maleate, and zinc fumarate wherein the hexedine and zinc are present in a weight ratio of from about 1:1 to 1:32.
Claim 3
Dependent Claim
21 words
The composition of claim 1 wherein hexedine is present in a concentration of from about 0.05 to about 1.0% by weight.
Claim 4
Dependent Claim
21 words
The composition of claim 1 wherein hexedine is present in a concentration of from about 0.05 to about 0.2% by weight.
Claim 5
Dependent Claim
22 words
The composition of claim 1 wherein the zinc ion is present in a concentration of from about 0.05 to 4.0% by weight.
Claim 6
Dependent Claim
28 words
The composition of claim 1 wherein said vehicle comprises at least one member selected from the group consisting of glycerol, water, ethanol, polyethylene glycol, propylene glycol and sorbitol.
Claim 7
Dependent Claim
33 words
A method of preventing or reducing the incidence of gingivitis comprising applying to the teeth and gingavae of the subject to be treated a therapeutically effective amount of the composition of claim 1.
Claim 8
Dependent Claim
14 words
The method of claim 6 wherein said composition is applied at least once daily.
Claim 9
Dependent Claim
12 words
The method of claim 6 wherein said composition is applied twice daily.
References Cited (Backward Citations)
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1990-05-11 | 1990-11-10 | 1991-05-12 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1994-05-11 | 1994-11-10 | 1995-05-12 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1998-05-11 | 1998-11-10 | 1999-05-12 | $7700.00 | Window Closed / Lapsed |