US4656028A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Encapsulated antacid
Assignee: Norcliff Thayer Inc
•
Filing: 1986-06-24
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Granted: 1987-04-07
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Expires: 2006-06-24
Abstract
Abstract A concentrated suspension of calcium carbonate particles in a liquid carrier that is compatible with a capsule shell material. The suspension is pourable and pumpable and may be used to provide antacid capsules.
Inventors
- 👤 Robert C. Cuca
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-04 11:29
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/48; A61K9/4841; A61K9/4866; A61K33/00; A61K33/06; A61K33/10; A61K9/4858
Claims Analysis
Total Claims: 12
Claim 1
Independent Claim
125 words
An antacid in unit dosage form, which comprises a soft gelatin capsule containing an effective amount of a pourable and pumpable antacid suspension, which comprises from about 60 to about 70%, by weight, based on the weight of the suspension, of calcium carbonate particles suspended in a pharmaceutically acceptable non-aqueous liquid carrier compatible with gelatin and containing less than about 5% by weight of water, based on the weight of the liquid carrier, said calcium carbonate particles containing more than about 50%, by weight, of particles in the range of from about 1 to about 10 microns, based on the weight of said particles, said calcium carbonate particles being irregularly shaped and having a plurality of edges formed by the intersection of substantially planar surfaces.
Claim 2
Dependent Claim
125 words
An antacid in unit dosage form, which comprises a soft gelatin capsule containing an effective amount of a pourable and pumpable antacid suspension, which comprises from about 60 to about 70%, by weight, based on the weight of the suspension, of calcium carbonate particles suspended in a pharmaceutically acceptable non-aqueous liquid carrier compatible with gelatin and containing less than about 5% by weight of water, based on the weight of the liquid carrier, said calcium carbonate particles containing more than about 50%, by weight, of particles in the range of from about 1 to about 10 microns, based on the weight of said particles, said calcium carbonate particles being irregularly shaped and having a plurality of edges formed by the intersection of substantially planar surfaces.
Claim 3
Dependent Claim
28 words
The antacid capsule according to claim 1, wherein at least 65% by weight of said particles is in said range of from about 1 to about 10 microns.
Claim 4
Dependent Claim
25 words
The antacid capsule according to claim 2, wherein the amount of said particles above about 10 microns is from 0 to about 10% by weight.
Claim 5
Dependent Claim
62 words
The antacid capsule according to claim 1, wherein from about 75 to about 100% of said particles is in said range of from about 1 to about 10 microns, from about 0 to about 15% is below about 1 micron and from about 0 to about 10% are above about 10 microns, all by weight based on the weight of said particles.
Claim 6
Dependent Claim
30 words
The antacid capsule according to claim 1, wherein said liquid carrier is a polyethylene glycol or mixture thereof having an average molecular weight of from about 200 to about 600.
Claim 7
Dependent Claim
13 words
The antacid capsule according to claim 5, wherein said liquid carrier is PEG-400.
Claim 8
Dependent Claim
12 words
The antacid capsule according to claim 1, which comprises a suspending agent.
Claim 9
Dependent Claim
19 words
The antacid capsule according to claim 1, which has an acid neutralization capacity of at least about 15 mEq./capsule.
Claim 10
Dependent Claim
19 words
The antacid capsule according to claim 4, which has an acid neutralization capacity of at least about 15 mEq./capsule.
Claim 11
Dependent Claim
19 words
The antacid capsule according to claim 7, which has an acid neutralization capacity of at least about 15 mEq./capsule.
Claim 12
Dependent Claim
22 words
The antacid capsule according to claim 9, wherein said suspension comprises from about 65 to about 70% of said calcium carbonate particles.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1990-04-06 | 1990-10-06 | 1991-04-07 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1994-04-06 | 1994-10-06 | 1995-04-07 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1998-04-06 | 1998-10-06 | 1999-04-07 | $7700.00 | Window Closed / Lapsed |