US4255413A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Gelatin capsule dosage unit containing triamterene
Assignee: SmithKline Beecham Corp
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Filing: 1979-10-01
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Granted: 1981-03-10
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Expires: 1999-10-01
Abstract
Abstract A gelatin capsule unit dosage form containing triamterene, 2,4,7-triamino-6-phenylpteridine, which results in rapid dissolution of the active ingredient. The dosage form comprises the addition of a combination of a surfactant and a carbonate or bicarbonate salt as diluents.
Inventors
- 👤 Elisabeth S. Rattie
- 👤 Louis J. Ravin
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-03 08:58
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/48; A61K9/4841; A61K9/485; A61K31/00; A61K31/33; A61K31/395; A61K31/495; A61K31/505; A61K9/4858
Claims Analysis
Total Claims: 9
Claim 1
Independent Claim
32 words
A gelatin capsule dosage unit comprising triamterene, and a rapid dissolution and dispersing amount of a combination of a surfactant and a calcium, ammonium, or alkali metal nontoxic carbonate or bicarbonate salt.
Claim 2
Dependent Claim
32 words
A gelatin capsule dosage unit comprising triamterene, and a rapid dissolution and dispersing amount of a combination of a surfactant and a calcium, ammonium, or alkali metal nontoxic carbonate or bicarbonate salt.
Claim 3
Dependent Claim
13 words
The gelatin capsule of claim 1 in which the surfactant is cetyldimethylpyridinium chloride.
Claim 4
Dependent Claim
14 words
The gelatin capsule of claim 2 in which the carbonate salt is calcium carbonate.
Claim 5
Dependent Claim
45 words
The gelatin capsule of claim 1 in which triamterene is present in an amount of from 10 mg. to 100 mg., the surfactant is present in an amount of from 0.5% to about 3.0%, and the salt is present from about 12% to about 35%.
Claim 6
Dependent Claim
33 words
A gelatin capsule dosage unit comprising triamterene, hydrochlorothiazide, and a rapid dissolution and dispersing amount of a combination of a surfactant, and a calcium, ammonium, or alkali metal nontoxic carbonate or bicarbonate salt.
Claim 7
Dependent Claim
33 words
A gelatin capsule dosage unit comprising triamterene, hydrochlorothiazide, and a rapid dissolution and dispersing amount of a combination of a surfactant, and a calcium, ammonium, or alkali metal nontoxic carbonate or bicarbonate salt.
Claim 8
Dependent Claim
20 words
The gelatin capsule of claim 5 in which the surfactant is cetyldimethylpyridinium chloride and the carbonate salt is calcium carbonate.
Claim 9
Dependent Claim
37 words
The gelatin capsule of claim 6 in which the triamterene is present in an amount of from 10 mg. to 100 mg. and the hydrochlorothiazide is present in an amount of from 2 mg. to 250 mg.
References Cited (Backward Citations)
US3081230A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1984-03-09 | 1984-09-08 | 1985-03-10 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1988-03-09 | 1988-09-08 | 1989-03-10 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1992-03-09 | 1992-09-08 | 1993-03-10 | $7700.00 | Window Closed / Lapsed |