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US4624959A
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N-{2-[(3-benzoyl-2-pyridyl)-thio]-ethyl}-N'-cyano-S-methyl-isothiourea, and use as anti-ulcer agents
Assignee: Richter Gedeon Vegyeszeti Gyar Nyrt
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Filing: 1985-10-03
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Granted: 1986-11-25
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Expires: 2005-10-03
Abstract
Abstract The compound N-{2-[(3-benzoyl-1-pyridyl)-thio]-ethyl}-N'-cyano-S-methyl-isothiourea and pharmaceutically acceptable acid addition salts thereof are disclosed as well as pharmaceutical compositions containing same and a method of treatment employing same. The compound or its acid addition salts are effective in treating gastric oedema and thus are useful in ulcer therapy.
Inventors
- 👤 Elemer Ezer
- 👤 Kalman Harsanyi
- 👤 Hajnalka Vikar nee Petho
- 👤 Judit Matuz
- 👤 Laszlo Szporny
- 👤 Eszter Cholnoky
- 👤 Csaba Kuthi
- 👤 Ferenc Trischler
- 👤 Bela Hegedus
- 👤 Marta Kapolnas nee Pap
- 👤 Anna Kallay nee Sohonyai
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-30 18:56
CPC Classifications
C; C07; C07D; C07D213/00; C07D213/02; C07D213/04; C07D213/60; C07D213/62; C07D213/70; A; A61; A61P; A61P1/00; A61P25/00; A61P25/04; A61P7/00; A61P7/02; C07D213/78; C07D213/79; C07D213/80; C07D213/81; C07D213/82; C07D401/00; C07D401/02; C07D401/12
Claims Analysis
Total Claims: 5
Claim 1
Independent Claim
9 words
N-{2-[(3-benzoyl-2-pyridyl)-thio]-ethyl}-N'-cyano-S-methyl-isothiourea or a pharmaceutically acceptable acid addition salt thereof.
Claim 2
Dependent Claim
9 words
N-{2-[(3-benzoyl-2-pyridyl)-thio]-ethyl}-N'-cyano-S-methyl-isothiourea or a pharmaceutically acceptable acid addition salt thereof.
Claim 3
Dependent Claim
38 words
A pharmaceutical composition for treating gastric oedema which comprises a therapeutically effective amount of the compound defined in claim 1 or a pharmaceutically acceptable acid addition salt thereof in association with a pharmaceutically acceptable inert carrier or diluent.
Claim 4
Dependent Claim
37 words
A method of treating gastric oedema in a mammal which comprises the step of administering to said mammal a therapeutically effective amount of the compound defined in claim 1 or a pharmaceutically acceptable acid addition salt thereof.
Claim 5
Dependent Claim
19 words
The method of treating gastic oedema in a mammal defined in claim 3 wherein the administration is oral administration.
References Cited (Backward Citations)
US4000285A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1989-11-24 | 1990-05-26 | 1990-11-25 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1993-11-24 | 1994-05-26 | 1994-11-25 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1997-11-24 | 1998-05-26 | 1998-11-25 | $7700.00 | Window Closed / Lapsed |