US4000285A
Expired / Lapsed
US
⏱️ 0.0 years remaining
2,3-bis-(3-acyl-2-thioureido)-pyridines
Assignee: GlaxoSmithKline LLC
•
Filing: 1976-02-10
•
Granted: 1976-12-28
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Expires: 1996-02-10
Abstract
Abstract New 2,3-bis-(3-acyl-2-thioureido)-pyridines having anthelmintic activity are prepared by reacting a diaminopyridine with acylthiocyanates.
Inventors
- 👤 Roger C. Parish
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-31 00:13
CPC Classifications
C; C07; C07D; C07D213/00; C07D213/02; C07D213/04; C07D213/60; C07D213/72; C07D213/75
Claims Analysis
Total Claims: 9
Claim 1
Independent Claim
31 words
A compound of the formula: ##STR2## in which R is 2-thienyl or 2-furyl; and X is hydrogen, lower alkyl, trifluoromethyl, halo, lower alkoxy, benzoyl, lower alkylthio, lower alkylsulfonyl, phenyloxy or phenylthio.
Claim 2
Dependent Claim
31 words
A compound of the formula: ##STR2## in which R is 2-thienyl or 2-furyl; and X is hydrogen, lower alkyl, trifluoromethyl, halo, lower alkoxy, benzoyl, lower alkylthio, lower alkylsulfonyl, phenyloxy or phenylthio.
Claim 3
Dependent Claim
10 words
A compound of claim 1 in which X is propylthio.
Claim 4
Dependent Claim
10 words
A compound of claim 1 in which X is phenylthio.
Claim 5
Dependent Claim
14 words
A compound of claim 1 in which R is 2-furyl and X is hydrogen.
Claim 6
Dependent Claim
14 words
A compound of claim 1 in which R is 2-furyl and X is 5-butyl.
Claim 7
Dependent Claim
14 words
A compound of claim 1 in which R is 2-thienyl and X is 4-methylthio.
Claim 8
Dependent Claim
36 words
The method of combatting helminthic infections in warm blooded animals afflicted with or susceptible to helminthic infections, comprising administering orally to said animals an effective but nontoxic quantity of a compound as claimed in claim 1.
Claim 9
Dependent Claim
38 words
An anthelmintic composition comprising an anthelmintically effective but nontoxic quantity of a compound as claimed in claim 1, dispersed uniformly throughout an inert carrier in amounts selected from the range of 1 to 300 mg./kg. per dosage unit.
References Cited (Backward Citations)
US3590045A
Cited
US3720682A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1979-12-28 | 1980-06-28 | 1980-12-28 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1983-12-28 | 1984-06-28 | 1984-12-28 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1987-12-28 | 1988-06-28 | 1988-12-28 | $7700.00 | Window Closed / Lapsed |