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US4582052A Expired / Lapsed US ⏱️ 0.0 years remaining

Povidone-iodine dispensing fiber

Assignee: DUNN IS ASSOCIATED AND LEWIS WAS FORMERLY ASSOCIATED WITH SOUTHERN RESEARCH INSTITUTE A CORP OF
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Filing: 1984-07-19
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Granted: 1986-04-15
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Expires: 2004-07-19
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Abstract

Abstract A fibrous article is formed of a polymer composition which incorporates povidone-iodine and provides for its sustained release.

Inventors

  • 👤 Richard L. Dunn
  • 👤 Danny H. Lewis
  • 👤 Leonard E. Laufe

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-24 17:14
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/0012; A61K9/0034; A61K9/0039; A01; A01N; A01N25/00; A01N25/34; A01N59/00; A01N59/12; Y; Y10; Y10S; Y10S525/00; Y10S525/937

Claims Analysis

Total Claims: 16
Claim 1
Independent Claim 42 words
An intrauterine device having a tail thread, said tail thread comprising a polymeric-formed fiber for controllably dispensing povidone-iodine complex in which said fiber comprises a molded thread-like polymeric structure incorporating said povidone-iodine complex in a form adapted for sustained slow release therefrom.
Claim 2
Dependent Claim 42 words
An intrauterine device having a tail thread, said tail thread comprising a polymeric-formed fiber for controllably dispensing povidone-iodine complex in which said fiber comprises a molded thread-like polymeric structure incorporating said povidone-iodine complex in a form adapted for sustained slow release therefrom.
Claim 3
Dependent Claim 28 words
A device as claimed in claim 1 wherein said polymeric-formed fiber is in monolithic form and in which said complex is dispersed in a polymer establishing said form.
Claim 4
Dependent Claim 23 words
A device as claimed in claim 2 wherein said polymer is selected from the group consisting of polyethylene, polypropylene, polycaprolactone, poly(Dl-lactide), and poly(L-lactide).
Claim 5
Dependent Claim 38 words
A device as claimed in claim 1 wherein said polymeric-formed fiber is in coaxial form and said complex is dispersed in one polymer establishing said form and is surrounded by another polymer establishing the rate of release therefrom.
Claim 6
Dependent Claim 24 words
A device as claimed in claim 4 wherein said one polymer is selected from the group consisting of polyethylene, polypropylene, polycaprolactone, poly(Dl-lactide), and poly(L-lactide).
Claim 7
Dependent Claim 39 words
A device as claimed in claim 1 wherein said polymeric-formed fiber is in coaxial form and one polymer forms a core and is surrounded by another polymer having said complex dispersed therein which forms a sheath around the core.
Claim 8
Dependent Claim 24 words
A device as claimed in claim 6 wherein said another polymer is selected from the group consisting of polyethylene, polypropylene, polycaprolactone, poly(Dl-lactide), and poly(L-lactide).
Claim 9
Dependent Claim 13 words
A device as claimed in claim 4 wherein said another polymer is nylon.
Claim 10
Dependent Claim 13 words
A device as claimed in claim 4 wherein said another polymer is polyester.
Claim 11
Dependent Claim 30 words
A device as claimed in claim 1 wherein said polymeric-structure incorporating said povidone-iodine is formed from a polymer selected from the group consisting of polyethylene, polypropylene, polycaprolactone, poly(Dl-lactide), and poly(L-lactide).
Claim 12
Dependent Claim 46 words
A device as claimed in claim 1 wherein said polymeric-formed fiber is in coaxial form and said complex is dispersed in one polymer establishing said form and is surrounded by the same said one polymer free of said complex and controlling the rate of release thereof.
Claim 13
Dependent Claim 110 words
An intrauterine device having a tail thread and said tail thread comprising a polymeric-formed fiber for controllably dispensing povidone-iodine complex in which said fiber comprises a molded thread-like monolithic solidified polymeric structure formed from a mixture of povidone-iodine complex and a polymer permeable to and having a melting point below the melting point of said povidone-iodine complex and having a molecular weight sufficiently high after said polymer and povidone-iodine complex are mixed, molded and solidified to maintain structural integrity in a solidified thread-like form and incorporating said povidone-iodine complex dispersed in said polymer after being molded in said solidified thread-like non-reservoired form and being adapted for sustained slow release therefrom.
Claim 14
Dependent Claim 110 words
An intrauterine device having a tail thread and said tail thread comprising a polymeric-formed fiber for controllably dispensing povidone-iodine complex in which said fiber comprises a molded thread-like monolithic solidified polymeric structure formed from a mixture of povidone-iodine complex and a polymer permeable to and having a melting point below the melting point of said povidone-iodine complex and having a molecular weight sufficiently high after said polymer and povidone-iodine complex are mixed, molded and solidified to maintain structural integrity in a solidified thread-like form and incorporating said povidone-iodine complex dispersed in said polymer after being molded in said solidified thread-like non-reservoired form and being adapted for sustained slow release therefrom.
Claim 15
Dependent Claim 128 words
A drug-dispensing tail thread in combination with an intrauterine implant, said thread comprising a polymeric-formed fiber for controllably dispensing povidone-iodine complex in which said fiber comprises a molded thread-like monolithic solidified polymeric structure formed from a mixture of a water soluble povidone-iodine complex having iodine organically bound to a polymer and a polymer permeable to and having a melting point below the melting point of said povidone-iodine complex and having a molecular weight sufficiently high after said polymer and povidone-iodine complex are mixed, molded and solidified to maintain structural integrity in a solidified thread-like form and incorporating said povidone-iodine complex dispersed in said polymer after being molded in said solidified thread-like form and being adapted for sustained slow release therefrom according to first order or pseudo zero-order kinetics.
Claim 16
Dependent Claim 128 words
A drug-dispensing tail thread in combination with an intrauterine implant, said thread comprising a polymeric-formed fiber for controllably dispensing povidone-iodine complex in which said fiber comprises a molded thread-like monolithic solidified polymeric structure formed from a mixture of a water soluble povidone-iodine complex having iodine organically bound to a polymer and a polymer permeable to and having a melting point below the melting point of said povidone-iodine complex and having a molecular weight sufficiently high after said polymer and povidone-iodine complex are mixed, molded and solidified to maintain structural integrity in a solidified thread-like form and incorporating said povidone-iodine complex dispersed in said polymer after being molded in said solidified thread-like form and being adapted for sustained slow release therefrom according to first order or pseudo zero-order kinetics.

References Cited (Backward Citations)

US3896819A Cited
US3996934A Cited
US3921636A Cited
US4014987A Cited
US4024871A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1989-04-14 1989-10-14 1990-04-15 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1993-04-14 1993-10-14 1994-04-15 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1997-04-14 1997-10-14 1998-04-15 $7700.00 Window Closed / Lapsed

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