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US4576110A Expired / Lapsed US ⏱️ 0.0 years remaining

Rotor having a chamber block with an absorbant plug

Assignee: Sorvall Products LP
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Filing: 1983-05-19
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Granted: 1986-03-18
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Expires: 2003-05-19
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Abstract

Abstract A chamber block for a centrifuge is provided with an inlet orifice, inlet channel, outlet channel and outlet orifice through which a sample of cells and supernatant may be centrifuged onto a deposition surface. The chamber block includes a recess sized to receive a plug of an absorbent material which withdraws excess supernatant from the deposition surface.

Inventors

  • 👤 John R. Wells

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-09 02:58
CPC Classifications
B; B04; B04B; B04B5/00; B04B5/04; B04B5/0407; G; G01; G01N; G01N1/00; G01N1/28; G01N1/2813; G01N2001/2846

Claims Analysis

Total Claims: 21
Claim 1
Independent Claim 165 words
A chamber block of the type having an inlet channel adapted to receive a sample of cells suspended in a supernatant and an outlet orifice opening on a face of the block through which the cells and supernatant pass under the influence of a centrifugal force field toward a deposition surface, wherein the improvement comprises a recess formed in the chamber block, the recess having an outlet which opens onto the same face as but is spaced from the outlet orifice, the recess having a first predetermined dimension over a first portion of its length which reduces to a lesser dimensioned portion adjacent the end of its length, the recess being sized to receive a plug of an absorbant material itself having a reduced dimensioned portion near an end thereof and to support the reduced dimensioned portion of the plug against the lesser dimensioned portion of the recess such that the end of the plug lies within a predetermined close dimension of the deposition surface.
Claim 2
Dependent Claim 165 words
A chamber block of the type having an inlet channel adapted to receive a sample of cells suspended in a supernatant and an outlet orifice opening on a face of the block through which the cells and supernatant pass under the influence of a centrifugal force field toward a deposition surface, wherein the improvement comprises a recess formed in the chamber block, the recess having an outlet which opens onto the same face as but is spaced from the outlet orifice, the recess having a first predetermined dimension over a first portion of its length which reduces to a lesser dimensioned portion adjacent the end of its length, the recess being sized to receive a plug of an absorbant material itself having a reduced dimensioned portion near an end thereof and to support the reduced dimensioned portion of the plug against the lesser dimensioned portion of the recess such that the end of the plug lies within a predetermined close dimension of the deposition surface.
Claim 3
Dependent Claim 33 words
The chamber block of claim 1 wherein the recess comprises a bore that extends through the block from rear to front to facilitate manipulation of a plug from the rear of the block.
Claim 4
Dependent Claim 22 words
The chamber block of claim 2 wherein the recess is arranged to support the plug in contacting relationship with the deposition surface.
Claim 5
Dependent Claim 157 words
A chamber block of the type having an inlet channel adapted to receive a sample of cells suspended in a supernatant and an outlet orifice opening on a surface of the block through which the cells and supernatant pass under the influence of a centrifugal force field toward a deposition surface wherein the improvement comprises a bore extending through the chamber block, the bore terminating is an opening on the same surface of the block as the outlet orifice, the opening of the bore being spaced from but disposed in proximity to the outlet orifice, the bore having a first predetermined dimension over a first portion of its length which tapers to a lesser dimension adjacent the end of its length, the bore being sized to receive a tapered plug of an absorbant material and to support the tapered plug against the taper of the bore to dispose the plug in contacting relationship with the deposition surface.
Claim 6
Dependent Claim 157 words
A chamber block of the type having an inlet channel adapted to receive a sample of cells suspended in a supernatant and an outlet orifice opening on a surface of the block through which the cells and supernatant pass under the influence of a centrifugal force field toward a deposition surface wherein the improvement comprises a bore extending through the chamber block, the bore terminating is an opening on the same surface of the block as the outlet orifice, the opening of the bore being spaced from but disposed in proximity to the outlet orifice, the bore having a first predetermined dimension over a first portion of its length which tapers to a lesser dimension adjacent the end of its length, the bore being sized to receive a tapered plug of an absorbant material and to support the tapered plug against the taper of the bore to dispose the plug in contacting relationship with the deposition surface.
Claim 7
Dependent Claim 21 words
The chamber block of claim 4 wherein the axis of the bore is disposed below the axis of the outlet orifice.
Claim 8
Dependent Claim 21 words
The chamber block of claim 4 wherein the axis of the bore is disposed above the axis of the outlet orifice.
Claim 9
Dependent Claim 33 words
The chamber block of claim 5 wherein the ratio of the area of the outlet orifice to the area of the opening of the bore lies within the range from ten-to-one to three-to-one.
Claim 10
Dependent Claim 33 words
The chamber block of claim 6 wherein the ratio of the area of the outlet orifice to the area of the opening of the bore lies within the range of ten-to-one to three-to-one.
Claim 11
Dependent Claim 28 words
The chamber block of claim 5 wherein a furrow is formed in the surface of the block that connects the outlet orifice and the opening of the bore.
Claim 12
Dependent Claim 28 words
The chamber block of claim 6 wherein a furrow is formed in the surface of the block that connects the outlet orifice and the opening of the bore.
Claim 13
Dependent Claim 166 words
A centrifuge comprising: a rotor having a chamber block support opening therein; a chamber block mounted in the support opening, the chamber block having an inlet channel adapted to receive a sample of cells suspended in a supernatant and an outlet orifice through which the cells and supernatant pass under the influence of a centrifugal force field toward a deposition surface, the chamber block having a recess formed therein, the recess having a first predetermined dimension over a first portion of its length which reduces to a lesser dimensioned portion adjacent the end of its length, the recess terminating in an opening: and an absorbant plug disposed within the recess itself having a reduced dimensioned portion near an end thereof, the recess being sized to receive the plug and to support the reduced dimensioned portion of the plug against the lesser dimensioned portion of recess such that the tip of the plug extends through the opening of the recess into contacting relationship with the deposition surface.
Claim 14
Dependent Claim 166 words
A centrifuge comprising: a rotor having a chamber block support opening therein; a chamber block mounted in the support opening, the chamber block having an inlet channel adapted to receive a sample of cells suspended in a supernatant and an outlet orifice through which the cells and supernatant pass under the influence of a centrifugal force field toward a deposition surface, the chamber block having a recess formed therein, the recess having a first predetermined dimension over a first portion of its length which reduces to a lesser dimensioned portion adjacent the end of its length, the recess terminating in an opening: and an absorbant plug disposed within the recess itself having a reduced dimensioned portion near an end thereof, the recess being sized to receive the plug and to support the reduced dimensioned portion of the plug against the lesser dimensioned portion of recess such that the tip of the plug extends through the opening of the recess into contacting relationship with the deposition surface.
Claim 15
Dependent Claim 33 words
The centrifuge of claim 11 wherein the recess comprises a bore that extends through the block from the rear to front to facilitate manipulation of the plug from the rear of the block.
Claim 16
Dependent Claim 20 words
The centrifuge of claim 12 wherein the axis of the bore is disposed below the axis of the outlet orifice.
Claim 17
Dependent Claim 20 words
The centrifuge of claim 12 wherein the axis of the bore is disposed above the axis of the outlet orifice.
Claim 18
Dependent Claim 32 words
The centrifuge of claim 13 wherein the ratio of the area of the outlet orifice to the area of the head of the bore lies within the range from ten-to-one to three-to-one.
Claim 19
Dependent Claim 32 words
The centrifuge of claim 14 wherein the ratio of the area of the outlet orifice to the area of the head of the bore lies within the range from ten-to-one to three-to-one.
Claim 20
Dependent Claim 27 words
The centrifuge of claim 12 wherein a furrow is formed in the surface of the block that connects the outlet orifice and the opening of the bore.
Claim 21
Dependent Claim 27 words
The centrifuge of claim 13 wherein a furrow is formed in the surface of the block that connects the outlet orifice and the opening of the bore.

References Cited (Backward Citations)

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US3870014A Cited
US4108109A Cited
US4197329A Cited
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USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1989-03-17 1989-09-16 1990-03-18 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1993-03-17 1993-09-16 1994-03-18 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1997-03-17 1997-09-16 1998-03-18 $7700.00 Window Closed / Lapsed

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