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Patent US4551148A successfully refreshed from Google Patents.
US4551148A
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Vaginal delivery systems and their methods of preparation and use
Assignee: Kv Pharmaceutical Co
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Filing: 1984-10-11
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Granted: 1985-11-05
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Expires: 2004-10-11
Abstract
Abstract Systems and their methods of preparation and use that release an active agent in a controlled manner for an extended period in a vaginal cavity environment. The systems are capable of delivering the active agent for periods greater than three hours at a predictable rate to a predetermined site, the vaginal cavity.
Inventors
- 👤 Thomas C. Riley, Jr.
- 👤 Charles P. Tharp
- 👤 Galen G. Lapka
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-03 08:03
CPC Classifications
A; A61; A61M; A61M31/00; A61M31/002; A61K; A61K9/00; A61K9/0012; A61K9/0034; Y; Y10; Y10S; Y10S424/00; Y10S424/14; Y10S424/15
Claims Analysis
Total Claims: 10
Claim 1
Independent Claim
58 words
Vaginal delivery systems which are bioadherent to the vaginal surfaces and which release an active agent in a controlled manner for at least three hours to a receptor site, site of action, site of absorption, or site of use consisting essentially of liquid or semi-solid adjacent unit cells having common lipoidal external phases, nonlipoidal internal phases and emulsifiers.
Claim 2
Dependent Claim
58 words
Vaginal delivery systems which are bioadherent to the vaginal surfaces and which release an active agent in a controlled manner for at least three hours to a receptor site, site of action, site of absorption, or site of use consisting essentially of liquid or semi-solid adjacent unit cells having common lipoidal external phases, nonlipoidal internal phases and emulsifiers.
Claim 3
Dependent Claim
15 words
The vaginal delivery systems of claim 1 wherein said phases form a liquid or semi-solid.
Claim 4
Dependent Claim
24 words
The vaginal delivery systems of claim 1 wherein said phases form to comprise an emulsion, emulsion/dispersion, double emulsion, suspension within an emulsion or mixture.
Claim 5
Dependent Claim
22 words
The vaginal delivery systems of claim 1 wherein at least a portion of the active agent is contained in said nonlipoidal phases.
Claim 6
Dependent Claim
13 words
The vaginal delivery systems of claim 1 wherein the active agent comprises nonoxynol-9.
Claim 7
Dependent Claim
13 words
The vaginal delivery systems of claim 1 wherein the active agent comprises nystatin.
Claim 8
Dependent Claim
15 words
The vaginal delivery systems of claim 1 wherein the active agent comprises a pH buffer.
Claim 9
Dependent Claim
20 words
The vaginal delivery systems of claim 1 wherein said nonlipoidal phases comprise at least 70% by volume of said systems.
Claim 10
Dependent Claim
19 words
The vaginal delivery systems of claim 1 wherein said nonlipoidal phases comprise either water, glycerine or a combination thereof.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1988-11-04 | 1989-05-06 | 1989-11-05 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1992-11-04 | 1993-05-06 | 1993-11-05 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1996-11-04 | 1997-05-06 | 1997-11-05 | $7700.00 | Window Closed / Lapsed |