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Pharmaceutical compound zinc glycerolate complex prepared by reacting zinc oxide and glycerol

Assignee: GLZINC PHARMACEUTICALS Ltd A CORP OF AUSTRALIA
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Filing: 1981-11-18
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Granted: 1985-10-01
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Expires: 2001-11-18
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Abstract

Abstract A pharmaceutical compound with therapeutic, prophylactic and cosmetic properties for human and veterinary use, being a zinc glycerolate complex formed as a reaction product of zinc oxide and glycerol having a platy morphology with generally hexagonal crystals (1/2/3) of relatively low thickness and high lubricity, with or without further reaction products or carriers.

Inventors

  • 👤 Reginald M. Taylor
  • 👤 Alan J. Brock

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-01 19:38
CPC Classifications
A; A61; A61K; A61K8/00; A61K8/18; A61K8/30; A61K8/33; A61K8/34; A61K8/345; A61K8/19; A61K8/27; A61L; A61L15/00; A61L15/16; A61L15/20; A61Q; A61Q19/00; C; C07; C07C; C07C29/00; C07C29/68; C07C29/70; C07C31/00; C07C31/28; A61K2800/00; A61K2800/40; A61K2800/58; A61Q17/00; A61Q17/04; A61Q9/00; A61Q9/02

Claims Analysis

Total Claims: 30
Claim 1
Independent Claim 85 words
A pharmaceutical compound formed by the process of reacting zinc oxide with glycerol by raising the temperature to about 260° C. and maintaining the temperature until reaction is completed to form C 3 H 6 O 3 Zn, cooling the reaction mixture and pouring the zinc glycerolate slurry so formed into water, adding copper to the said slurry and shaking to cause zinc to be replaced by the said copper, and filtering the residue and washing and drying to produce a modified zinc glycerolate complex.
Claim 2
Dependent Claim 85 words
A pharmaceutical compound formed by the process of reacting zinc oxide with glycerol by raising the temperature to about 260° C. and maintaining the temperature until reaction is completed to form C 3 H 6 O 3 Zn, cooling the reaction mixture and pouring the zinc glycerolate slurry so formed into water, adding copper to the said slurry and shaking to cause zinc to be replaced by the said copper, and filtering the residue and washing and drying to produce a modified zinc glycerolate complex.
Claim 3
Dependent Claim 20 words
The pharmaceutical compound according to claim 1 wherein the copper is added as an aqueous solution of a copper salt.
Claim 4
Dependent Claim 82 words
A composition formed by the process of reacting zinc oxide with glycerol by raising the temperature to about 260° C. and, maintaining the temperature until reaction is complete to form C 3 H 6 O 3 Zn, cooling the reaction mixture and pouring the slurry so formed into water, filtering, washing and drying to isolate zinc glycerolate, and blending into the zinc glycerolate and oleaginous substance for application of the blend to the skin as a therapeutic or prophylactic or cosmetic substance.
Claim 5
Dependent Claim 82 words
A composition formed by the process of reacting zinc oxide with glycerol by raising the temperature to about 260° C. and, maintaining the temperature until reaction is complete to form C 3 H 6 O 3 Zn, cooling the reaction mixture and pouring the slurry so formed into water, filtering, washing and drying to isolate zinc glycerolate, and blending into the zinc glycerolate and oleaginous substance for application of the blend to the skin as a therapeutic or prophylactic or cosmetic substance.
Claim 6
Dependent Claim 45 words
A composition according to claim 3 wherein the oleaginous substance is a mixture of glycerol monostearate, paraffin oil, lanolin, glycerol and stearic acid to produce a shaving cream, the mixture being further mixed with potassium hydroxide and water and blended with the zinc glycerolate complex.
Claim 7
Dependent Claim 38 words
A composition according to claim 3 wherein the oleaginous substance is oleic acid, peanut oil and lanolin mixed together and melted and applied to the zinc glycerolate while blending in calcium hydroxide solution to form a sun screen.
Claim 8
Dependent Claim 73 words
A pharmaceutical which is a mixture of a zinc glycerolate complex having the formula C 3 H 6 O 3 Zn formed as a reaction product of zinc oxide and glycerol at a temperature range between 120° and 300° C., having a platy morphology with generally hexagonal crystals of relatively low thickness and high lubricity and an oleaginous substance suitable for application to the skin as a therapeutic or prophylactic or cosmetic substance.
Claim 9
Dependent Claim 73 words
A pharmaceutical which is a mixture of a zinc glycerolate complex having the formula C 3 H 6 O 3 Zn formed as a reaction product of zinc oxide and glycerol at a temperature range between 120° and 300° C., having a platy morphology with generally hexagonal crystals of relatively low thickness and high lubricity and an oleaginous substance suitable for application to the skin as a therapeutic or prophylactic or cosmetic substance.
Claim 10
Dependent Claim 45 words
A pharamceutical according to claim 6 wherein the oleaginous substance is a mixture of glycerol monostearate, paraffin oil, lanolin, glycerol and stearic acid to produce a shaving cream, the mixture being further mixed with potassium hydroxide and water and blended with the zinc glycerolate complex.
Claim 11
Dependent Claim 38 words
A pharmaceutical according to claim 6 wherein the oleaginous substance is oleic acid, peanut oil and lanolin mixed together and melted and applied to the zine glycerolate while blending in calcium hydroxide solution to form a sun screen.
Claim 12
Independent Claim 67 words
A method of applying a therapeutic or prophylactic or cosmetic material to the skin comprising applying to the skin a zinc glycerolate complex having the formula C 3 H 6 O 3 Zn formed as a reaction product of zinc oxide and glycerol at a temperature range between 120° and 300° C., having a platy morphology with generally hexagonal crystals of relatively low thickness and high lubricity.
Claim 13
Independent Claim 67 words
A method of applying a therapeutic or prophylactic or cosmetic material to the skin comprising applying to the skin a zinc glycerolate complex having the formula C 3 H 6 O 3 Zn formed as a reaction product of zinc oxide and glycerol at a temperature range between 120° and 300° C., having a platy morphology with generally hexagonal crystals of relatively low thickness and high lubricity.
Claim 14
Dependent Claim 78 words
A method according to claim 9 wherein the zinc glycerolate complex is formed by the process of reacting zinc oxide or zinc acetate with glycerol in the proportions of about 50 gms zinc oxide or zinc acetate to 500 gms glycerol, raising the temperature of the mix to about 260° C. and maintaining the temperature until reaction is completed, cooling and pouring the mixture so formed into water, filtering, washing and drying to isolate the zinc glycerolate complex.
Claim 15
Dependent Claim 24 words
A method of applying a therapeutic or prophylactic or cosmetic material to the skin comprising applying to the skin the composition of claim 1.
Claim 16
Independent Claim 101 words
A method of applying a therapeutic or prophylactic or cosmetic material to the skin comprising applying to the skin a composition formed by the process of reacting zinc oxide with glycerol wherein a colouring dye is added to the zinc oxide before forming an admixture with the glycerol, raising the temperature of the mixture to about 260° C. and maintaining the temperature until reaction is completed to form C 3 H 6 O 3 Zn, cooling the reaction mixture and pouring the slurry so formed into water, filtering the residue and washing and drying to produce the coloured zinc glycerolate complex.
Claim 17
Independent Claim 101 words
A method of applying a therapeutic or prophylactic or cosmetic material to the skin comprising applying to the skin a composition formed by the process of reacting zinc oxide with glycerol wherein a colouring dye is added to the zinc oxide before forming an admixture with the glycerol, raising the temperature of the mixture to about 260° C. and maintaining the temperature until reaction is completed to form C 3 H 6 O 3 Zn, cooling the reaction mixture and pouring the slurry so formed into water, filtering the residue and washing and drying to produce the coloured zinc glycerolate complex.
Claim 18
Dependent Claim 25 words
A method according to claim 12 wherein the dye is a mixture of certolake erythrosine and certolake tartrazine to produce a tan coloured zine glycerolate.
Claim 19
Dependent Claim 24 words
A method of applying a therapeutic or prophylactic or cosmetic material to the skin comprising applying to the skin the composition of claim 3.
Claim 20
Dependent Claim 45 words
A method according to claim 14 wherein the oleaginous substance is a mixture of glycerol monostearate, paraffin oil, lanolin, glyercol and stearic acid the mixture being further mixed with potassium hydroxide and water and blended with the zinc glycerolate complex to form a shaving cream.
Claim 21
Dependent Claim 38 words
A method according to claim 14 wherein the oleaginous substance is oleic acid, peanut oil and lanolin mixed together and melted and applied to the zinc glycerolate while blending in calcium hydroxide solution to form a sun screen.
Claim 22
Dependent Claim 24 words
A method of applying a therapeutic or prophylactic or cosmetic material to the skin comprising applying to the skin the composition of claim 6.
Claim 23
Dependent Claim 24 words
A method of applying a therapeutic or prophylactic or cosmetic material to the skin comprising applying to the skin the composition of claim 7.
Claim 24
Dependent Claim 24 words
A method of applying a therapeutic or prophylactic or cosmetic material to the skin comprising applying to the skin the composition of claim 8.
Claim 25
Dependent Claim 32 words
A compound according to claim 1 wherein the complex is prepared by reacting 80 to 100 parts by weight of zinc oxide or zinc acetate to 100 parts by weight of glycerol.
Claim 26
Dependent Claim 115 words
A composition formed by the process of reacting zinc oxide or zinc acetate with glycerol wherein a colouring dye is added to the zinc oxide or zinc acetate before forming an admixture with the glycerol, raising the temperature of the mixture to about 260° C. and maintaining the temperature until reaction is completed to form C 3 H 6 O 3 Zn, cooling the reaction mixture and pouring the slurry so formed into water, filtering the residue and washing and drying to produce the coloured zinc glycerolate complex there being employed 80 to 100 parts by weight of zinc oxide or zinc acetate to 1000 parts by weight of glycerol to the form the complex.
Claim 27
Dependent Claim 115 words
A composition formed by the process of reacting zinc oxide or zinc acetate with glycerol wherein a colouring dye is added to the zinc oxide or zinc acetate before forming an admixture with the glycerol, raising the temperature of the mixture to about 260° C. and maintaining the temperature until reaction is completed to form C 3 H 6 O 3 Zn, cooling the reaction mixture and pouring the slurry so formed into water, filtering the residue and washing and drying to produce the coloured zinc glycerolate complex there being employed 80 to 100 parts by weight of zinc oxide or zinc acetate to 1000 parts by weight of glycerol to the form the complex.
Claim 28
Dependent Claim 32 words
A composition according to claim 3 wherein the complex is prepared by reacting 80 to 100 parts by weight of zinc oxide or zinc acetate to 1000 parts by weight of glycerol.
Claim 29
Dependent Claim 32 words
A composition according to claim 6 wherein the complex is prepared by reacting 80 to 100 parts by weight of zinc oxide or zinc acetate to 1000 parts by weight of glycerol.
Claim 30
Dependent Claim 32 words
A method according to claim 9 wherein the complex is formed by reacting 80 to 100 parts by weight of zinc oxide or zinc acetate to 1000 parts by weight of glycerol.

References Cited (Backward Citations)

US2719811A Cited
US2595371A Cited
US3859236A Cited
US3996346A Cited
US4160821A Cited
US4316852A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1988-09-30 1989-04-01 1989-10-01 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1992-09-30 1993-04-01 1993-10-01 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1996-09-30 1997-04-01 1997-10-01 $7700.00 Window Closed / Lapsed

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