Patent US4534980A successfully refreshed from Google Patents.
US4534980A
Expired / Lapsed
US
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Antiinflammatory and antipyretic cream
Assignee: Abbott Japan Co Ltd
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Filing: 1984-07-23
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Granted: 1985-08-13
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Expires: 2004-07-23
Abstract
Abstract Creams for external or topical use comprising ketoprofen as an effective component and crotamiton as an agent for preventing crystalline precipitation of the effective component. The creams possess an antiinflammatory and antipyretic effect and are excellent in permeation and absorption into the skin which enables the topical and external use of the creams.
Inventors
- 👤 Yasuo Itoh
- 👤 Hideo Kato
- 👤 Kugako Matsumura
- 👤 Tomoyasu Nishikawa
- 👤 Akira Hisano
- 👤 Takehisa Yamada
- 👤 Eiichi Koshinaka
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-07 20:07
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/0012; A61K9/0014; A61K31/00; A61K31/16; A61K31/165; A61K31/185; A61K31/19; A61K47/00; A61K47/06; A61K47/16; A61K47/18; A61P; A61P17/00; A61P25/00; A61P25/04; A61P29/00
Claims Analysis
Total Claims: 3
Claim 1
Independent Claim
48 words
An antiinflammatory and antipyretic cream comprising ketoprofen and crotamiton as an agent for preventing crystalline precipitation, crotamiton being in a ratio of 0.4 to 1.0 part by weight per 1.0 part by weight of ketoprofen; and; a pH range of said cream being adjusted to 6.5 to 7.5.
Claim 2
Dependent Claim
48 words
An antiinflammatory and antipyretic cream comprising ketoprofen and crotamiton as an agent for preventing crystalline precipitation, crotamiton being in a ratio of 0.4 to 1.0 part by weight per 1.0 part by weight of ketoprofen; and; a pH range of said cream being adjusted to 6.5 to 7.5.
Claim 3
Dependent Claim
80 words
The antiinflammatory and antipyretic cream of claim 1 which contains 1.0 to 5.0 wt% of ketoprofen and 0.4 to 5.0 wt% of crotamiton and, further containing 1 to 20 wt% of a higher alcohol, 5 to 20 wt% of an oily substance, 1.0 to 10.0 wt% of a surfactant, 5 to 20 wt% of a humectant, 0.01 to 0.5 wt% of a antiseptic agent, 0.1 to 4.5 wt% of a pH controlling agent and 50 to 70 wt% of water.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1988-08-12 | 1989-02-11 | 1989-08-13 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1992-08-12 | 1993-02-11 | 1993-08-13 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1996-08-12 | 1997-02-11 | 1997-08-13 | $7700.00 | Window Closed / Lapsed |