Patent US4529521A successfully refreshed from Google Patents.
US4529521A
Expired / Lapsed
US
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Method and apparatus for analyzing latexes
Assignee: Dow Chemical Co
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Filing: 1983-08-26
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Granted: 1985-07-16
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Expires: 2003-08-26
Abstract
Abstract A method for analyzing the serum phase of a latex solution by permeating low molecular weight components present in the serum phase for a known amount of time through a size selective permeable membrane to a dialysate fluid and sequentially injecting the dialysate fluid into a liquid chromatograph for subsequent analysis.
Inventors
- 👤 Hernan J. Cortes
- 👤 James C. Davis
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-08 23:23
CPC Classifications
B; B01; B01D; B01D61/00; B01D61/24; B01D61/243; B01D61/28; G; G01; G01N; G01N30/00; G01N30/02; G01N30/04; G01N30/06; G01N30/14; G01N2030/146
Claims Analysis
Total Claims: 11
Claim 1
Independent Claim
138 words
A method of analyzing the serum phase of a latex solution comprising the steps of: (a) contacting one side of a size selective molecularly permeable membrane with a latex solution to be analyzed, the membrane being permeable to low molecular weight components; (b) contacting the opposite side of the membrane with dialysate fluid; (c) permeating low molecular weight components in the serum phase of the latex solution through the membrane to the dialysate fluid for a known amount of time; (d) displacing the dialysate fluid from contact with the membrane after a known amount of elapsed permeation time; (e) capturing an aliquot sample of the displaced dialysate fluid; (f) adding the captured sample to a chromatographic column; (g) adding eluent to the column to elute the sample; and (h) analyzing the sample for serum phase species of interest.
Claim 2
Independent Claim
138 words
A method of analyzing the serum phase of a latex solution comprising the steps of: (a) contacting one side of a size selective molecularly permeable membrane with a latex solution to be analyzed, the membrane being permeable to low molecular weight components; (b) contacting the opposite side of the membrane with dialysate fluid; (c) permeating low molecular weight components in the serum phase of the latex solution through the membrane to the dialysate fluid for a known amount of time; (d) displacing the dialysate fluid from contact with the membrane after a known amount of elapsed permeation time; (e) capturing an aliquot sample of the displaced dialysate fluid; (f) adding the captured sample to a chromatographic column; (g) adding eluent to the column to elute the sample; and (h) analyzing the sample for serum phase species of interest.
Claim 3
Dependent Claim
16 words
The method of claim 1 wherein the size selective molecularly permeable membrane is a hollow fiber.
Claim 4
Dependent Claim
11 words
The method of claim 1 wherein the dialysate fluid is water.
Claim 5
Dependent Claim
18 words
The method of claim 1 wherein the aliquot of dialysate fluid is captured in a sample injection valve.
Claim 6
Dependent Claim
14 words
The method of claim 4 wherein the eluent is H 2 SO 4 .
Claim 7
Dependent Claim
109 words
In a liquid chromatography apparatus with a chromatographic column, a sample injection valve, a pump for pumping eluent through the column, and a detector, the improvement which comprises: (a) a membrane device in communication with the sample injection valve, said device comprising: a reservoir adapted for containing latex solution to be analyzed and a size selective molecularly permeable membrane having one side of the membrane in contact with the latex solution and having the opposite side of the membrane in contact with a dialysate fluid; and (b) means communicating with the membrane device for displacing the dialysate fluid from contact with the membrane directly to the sample injection valve.
Claim 8
Dependent Claim
109 words
In a liquid chromatography apparatus with a chromatographic column, a sample injection valve, a pump for pumping eluent through the column, and a detector, the improvement which comprises: (a) a membrane device in communication with the sample injection valve, said device comprising: a reservoir adapted for containing latex solution to be analyzed and a size selective molecularly permeable membrane having one side of the membrane in contact with the latex solution and having the opposite side of the membrane in contact with a dialysate fluid; and (b) means communicating with the membrane device for displacing the dialysate fluid from contact with the membrane directly to the sample injection valve.
Claim 9
Dependent Claim
16 words
The apparatus of claim 1 wherein the size selective molecularly permeable membrane is a hollow fiber.
Claim 10
Dependent Claim
11 words
The apparatus of claim 1 wherein the dialysate fluid is water.
Claim 11
Dependent Claim
16 words
The apparatus of claim 1 wherein the means for displacing the dialysate fluid is a syringe.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1988-07-15 | 1989-01-14 | 1989-07-16 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1992-07-15 | 1993-01-14 | 1993-07-16 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1996-07-15 | 1997-01-14 | 1997-07-16 | $7700.00 | Window Closed / Lapsed |