US4526989A
Expired / Lapsed
US
⏱️ 0.0 years remaining
1,4-Bis (substituted-amino)-5,8-dihydroxy-anthraquinones and leuco bases thereof
Assignee: Wyeth Holdings LLC
•
Filing: 1979-10-23
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Granted: 1985-07-02
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Expires: 1999-10-23
Abstract
Abstract This disclosure describes symmetrical 1,4-bis (substituted-amino)-5,8-dihydroxyanthraquinones useful as chelating agents and for inhibiting the growth of transplanted mouse tumors.
Inventors
- 👤 Keith C. Murdock
- 👤 Frederick E. Durr
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-24 02:27
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/13; A61K31/135
Claims Analysis
Total Claims: 18
Claim 1
Independent Claim
22 words
A compound selected from the group consisting of 1,4-bis[(2-aminoethyl)amino]-5,8-dihydroxyanthraquinone, the leuco base and tautomer thereof, and the pharmacologically acceptable acid-addition salts thereof.
Claim 2
Dependent Claim
22 words
A compound selected from the group consisting of 1,4-bis[(2-aminoethyl)amino]-5,8-dihydroxyanthraquinone, the leuco base and tautomer thereof, and the pharmacologically acceptable acid-addition salts thereof.
Claim 3
Dependent Claim
8 words
The aromatic free base according to claim 1.
Claim 4
Dependent Claim
8 words
The leuco free base according to claim 1.
Claim 5
Dependent Claim
17 words
The acid-addition salt of the aromatic base according to claim 1 wherein the acid is sulfuric acid.
Claim 6
Dependent Claim
17 words
The acid-addition salt of the leuco base according to claim 1 wherein the acid is phosphoric acid.
Claim 7
Dependent Claim
17 words
The acid-addition salt of the aromatic base according to claim 1 wherein the acid is hydrochloric acid.
Claim 8
Dependent Claim
17 words
The acid-addition salt of the leuco base according to claim 1 wherein the acid is hydrobromic acid.
Claim 9
Dependent Claim
17 words
The acid-addition salt of the aromatic base according to claim 1 wherein the acid is sulfamic acid.
Claim 10
Dependent Claim
17 words
The acid-addition salt of the leuco base according to claim 1 wherein the acid is citric acid.
Claim 11
Dependent Claim
17 words
The acid-addition salt of the aromatic base according to claim 1 wherein the acid is lactic acid.
Claim 12
Dependent Claim
17 words
The acid-addition salt of the leuco base according to claim 1 wherein the acid is malic acid.
Claim 13
Dependent Claim
17 words
The acid-addition salt of the aromatic base according to claim 1 wherein the acid is succinic acid.
Claim 14
Dependent Claim
17 words
The acid-addition salt of the leuco base according to claim 1 wherein the acid is tartaric acid.
Claim 15
Dependent Claim
17 words
The acid-addition salt of the aromatic base according to claim 1 wherein the acid is acetic acid.
Claim 16
Dependent Claim
17 words
The acid-addition salt of the leuco base according to claim 1 wherein the acid is benzoic acid.
Claim 17
Dependent Claim
17 words
The acid-addition salt of the aromatic base according to claim 1 wherein the acid is gluconic acid.
Claim 18
Dependent Claim
17 words
The acid-addition salt of the leuco base according to claim 1 wherein the acid is ascorbic acid.
References Cited (Backward Citations)
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Cited
GB1157506A
Cited
US4051155A
Cited
US4197249A
Cited
US4310666A
Cited
US4138415A
Cited
US4278689A
Cited
US4428882A
Cited
US4456552A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1988-07-01 | 1988-12-31 | 1989-07-02 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1992-07-01 | 1992-12-31 | 1993-07-02 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1996-07-01 | 1996-12-31 | 1997-07-02 | $7700.00 | Window Closed / Lapsed |