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US4456552A Expired / Lapsed US ⏱️ 0.0 years remaining

1,4-Bis(substituted-amino)-5,8-dihydroxyanthraquinones and leuco bases thereof

Assignee: Immunex Corp
•
Filing: 1981-03-02
•
Granted: 1984-06-26
•
Expires: 2001-03-02
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Abstract

Abstract This disclosure describes symmetrical 1,4-bis(substituted-amino)-5,8-dihydroxyanthraquinones useful as chelating agents and for inhibiting the growth of transplanted mouse tumors.

Inventors

  • 👤 Keith C. Murdock
  • 👤 Frederick E. Durr

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-26 17:22
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/13; A61K31/135

Claims Analysis

Total Claims: 10
Claim 1
Independent Claim 22 words
A compound selected from the group consisting of 1,4-bis[2-(2-aminoethylamino)ethylamino]-5,8-dihydroxyanthaquinone, the leuco base and tautomer thereof and the pharmacologically acceptable acid-addition salts thereof.
Claim 2
Dependent Claim 22 words
A compound selected from the group consisting of 1,4-bis[2-(2-aminoethylamino)ethylamino]-5,8-dihydroxyanthaquinone, the leuco base and tautomer thereof and the pharmacologically acceptable acid-addition salts thereof.
Claim 3
Dependent Claim 22 words
A compound selected from the group consisting of 1,4-bis[2-(2-methylaminoethylamino)ethylamino]-5,8-dihydroxyanthraquinone, the leuco base and tautomer thereof and the pharmacologically acceptable acid-addition salts thereof.
Claim 4
Dependent Claim 22 words
A compound selected from the group consisting of 1,4-bis[2-(2-methylaminoethylamino)ethylamino]-5,8-dihydroxyanthraquinone, the leuco base and tautomer thereof and the pharmacologically acceptable acid-addition salts thereof.
Claim 5
Dependent Claim 22 words
A compound selected from the group consisting of 1,4-bis[2-(2-dimethylaminoethylamino)ethylamino]-5,8-dihydroxyanthraquinone, the leuco base and tautomer thereof and the pharmacologically acceptable acid-addition salts thereof.
Claim 6
Dependent Claim 22 words
A compound selected from the group consisting of 1,4-bis[2-(2-dimethylaminoethylamino)ethylamino]-5,8-dihydroxyanthraquinone, the leuco base and tautomer thereof and the pharmacologically acceptable acid-addition salts thereof.
Claim 7
Dependent Claim 22 words
A compound selected from the group consisting of 1,4-bis[2-(2,3-dihydroxypropylamino)ethylamino]-5,8-dihydroxyanthraquinone, the leuco base and tautomer thereof and the pharmacologically acceptable acid-addition salts thereof.
Claim 8
Dependent Claim 22 words
A compound selected from the group consisting of 1,4-bis[2-(2,3-dihydroxypropylamino)ethylamino]-5,8-dihydroxyanthraquinone, the leuco base and tautomer thereof and the pharmacologically acceptable acid-addition salts thereof.
Claim 9
Dependent Claim 22 words
A compound selected from the group consisting of 1,4-bis[2-(N-(β-hydroxyethyl)trifluoroacetamido)ethylamino]-5,8-dihydroxyanthraquinone, the leuco base and tautomer thereof and the pharmacologically acceptable acid-addition salts thereof.
Claim 10
Dependent Claim 22 words
A compound selected from the group consisting of 1,4-bis[2-(N-(β-hydroxyethyl)trifluoroacetamido)ethylamino]-5,8-dihydroxyanthraquinone, the leuco base and tautomer thereof and the pharmacologically acceptable acid-addition salts thereof.

References Cited (Backward Citations)

GB1157506A Cited
US3646072A Cited
US4166822A Cited
US3857864A Cited
US3904660A Cited
GB1475081A Cited
US4197249A Cited
US4170564A Cited
US4310666A Cited
US4278689A Cited
US4296030A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1987-06-26 1987-12-26 1988-06-26 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1991-06-26 1991-12-26 1992-06-26 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1995-06-26 1995-12-26 1996-06-26 $7700.00 Window Closed / Lapsed

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