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US4522814A
Expired / Lapsed
US
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Composition of matter from Cryptosiphonia woodii useful for the treatment of herpes simplex virus
Assignee: Individual
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Filing: 1982-11-05
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Granted: 1985-06-11
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Expires: 2002-11-05
Abstract
Abstract A water extract of homogenized Cryptosiphonia woodii is useful for the treatment of herpes simplex viral infections. The active agent in the extract is a polysaccharide containing glucose and galactose. Herpes infections may be treated in subjects, e.g. human patients, by administering to the subject an effective amount of an aqueous extract of C. woodii, particularly a water extract. This treatment method is effective for treating subjects both prior to and subsequent to infection. It may involve topical application to alleviate symptoms associated with herpes infections or desirably may be systemic, e.g. by oral administration, to eradicate the virus and thereby prevent symptom recurrence.
Inventors
- 👤 Arthur M. Nonomura
- 👤 Raphael Pappo
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-05 23:42
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/70; A61K31/715
Claims Analysis
Total Claims: 16
Claim 1
Independent Claim
51 words
A composition of matter useful for the treatment of herpes simplex virus infection in a subject comprising an unbuffered water extract of homogenized Cryptosiphonia woodii wherein the extract contains a polysaccharide comprising glucose and galactose units and more than about 5.0% sulfur by weight based on the weight of the extract.
Claim 2
Dependent Claim
51 words
A composition of matter useful for the treatment of herpes simplex virus infection in a subject comprising an unbuffered water extract of homogenized Cryptosiphonia woodii wherein the extract contains a polysaccharide comprising glucose and galactose units and more than about 5.0% sulfur by weight based on the weight of the extract.
Claim 3
Dependent Claim
30 words
A therapeutic composition useful for the treatment of herpes simplex virus infection in a subject comprising an effective antiviral amount of the composition of claim 1 and a suitable carrier.
Claim 4
Dependent Claim
12 words
A therapeutic composition in accordance with claim 2 adapted for topical application.
Claim 5
Dependent Claim
12 words
A therapeutic composition in accordance with claim 2 adapted for systemic application.
Claim 6
Dependent Claim
20 words
A composition of matter in accordance with claim 1 having a pH in the range from about 4.5 to 5.5.
Claim 7
Independent Claim
56 words
A method of treating a herpes simplex virus infection in a subject comprising administering to said subject an effective antiviral amount of an unbuffered aqueous extract of homogenized Cryptosiphonia woodii wherein the extract contains a polysaccharide comprising glucose and galactose units and more than about 5.0% sulfur by weight based on the weight of the extract.
Claim 8
Independent Claim
56 words
A method of treating a herpes simplex virus infection in a subject comprising administering to said subject an effective antiviral amount of an unbuffered aqueous extract of homogenized Cryptosiphonia woodii wherein the extract contains a polysaccharide comprising glucose and galactose units and more than about 5.0% sulfur by weight based on the weight of the extract.
Claim 9
Dependent Claim
14 words
A method in accordance with claim 6 wherein said subject is a human patient.
Claim 10
Dependent Claim
15 words
A method in accordance with claim 6 wherein the aqueous extract is a water extract.
Claim 11
Dependent Claim
22 words
A method in accordance with claim 8 wherein the water extract has a pH in the range from about 4.5 to 5.5.
Claim 12
Dependent Claim
12 words
A method in accordance with claim 6 wherein the administration is topical.
Claim 13
Dependent Claim
12 words
A method in accordance with claim 6 wherein the administration is systemic.
Claim 14
Dependent Claim
15 words
A method in accordance with claim 6 wherein the administration is effected prior to infection.
Claim 15
Dependent Claim
15 words
A method in accordance with claim 6 wherein the administration is effected subsequent to infection.
Claim 16
Dependent Claim
13 words
A method in accordance with claim 11 wherein the systemic administration is oral.
References Cited (Backward Citations)
US4229440A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1988-06-10 | 1988-12-10 | 1989-06-11 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1992-06-10 | 1992-12-10 | 1993-06-11 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1996-06-10 | 1996-12-10 | 1997-06-11 | $7700.00 | Window Closed / Lapsed |