Pharmaceutical composition containing the polysaccharide KGF-C as active ingredient

Claim 1

A composition effective for the treatment of sarcoma-180 and Ehrlich carcinoma tumors, comprising a physiologically acceptable excipient and an effective amount of KGF-C having the following physical and chemical properties: (1) Appearance: tasteless and odorless white powder having a little hygroscopicity; (2) Solubility: soluble in water and pyridine and insoluble in alcohol, glacial acetic acid, acetone, benzene, carbon tetrachloride, chloroform, ether and tetrahydrofuran; (3) The pH of 1% aqueous solution is 6.89; (4) Sugar qualitative reaction: with respect to the 1% aqueous solution and liquid hydrolyzate thereof, Molish tests are positive in both 1% aqueous solution and 0.1% liquid hydrolyzate and Tollens reaction test is negative in 1% aqueous solution but is positive in 0.1% liquid hydrolyzate; (5) Specific optical rotation: (α) D 20 =+62.0° C. (C=1, water); (6) Sugar content: 99% is shown by phenol sulfuric acid method; KGF-C is composed of polysaccharide as principal component, and a very small amount of nitrogenous component; (7) Sugar composition: when KGF-C is hydrolyzed by 0.5% H 2 SO 4 at 110° C. for 5 hours and the sugar composition is determined by thin layer chromatography and gas chromatography, the results show that it is composed of glucose and galactose in the ratio of 1:1; (8) Ultraviolet absorption spectrum: no particular absorption is observed; (9) Infrared absorption spectrum: the spectrum is shown in the drawing; and (10) Elemental analysis: C: 41.83%, H: 6.19%, N: 0.20%, S: below 0.2% and P: below 0.2%.