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US4515585A Expired / Lapsed US ⏱️ 0.0 years remaining

System for parenteral administration of agent

Assignee: Alza Corp
•
Filing: 1983-10-31
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Granted: 1985-05-07
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Expires: 2003-10-31
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Abstract

Abstract A parenteral delivery system is disclosed for administering a beneficial agent to a recipient. The system comprises (a) a primary container of a medical fluid; (b) a primary drip chamber in fluid communication with the primary container; (c) a primary formulation chamber in fluid communication with the primary drip chamber and housing an agent dispensing device or a beneficial agent; (d) a secondary container of a medical fluid; (e) a secondary drip chamber in fluid communication with the secondary container; (f) a secondary formulation chamber in fluid communication with the secondary drip chamber and housing an agent dispensing device or a beneficial agent; and (g) a common tubing in communication with the primary formulation chamber and the secondary formulation chamber for communicating the system with the recipient.

Inventors

  • 👤 John Urquhart
  • 👤 Felix Theeuwes

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-05 14:53
CPC Classifications
A; A61; A61M; A61M5/00; A61M5/14; A61M5/1407; A61M5/142; A61M5/145; A61M2005/14513

Claims Analysis

Total Claims: 10
Claim 1
Independent Claim 305 words
A parenteral delivery system for administering a beneficial agent formulation to an animal, the system comprising: (a) a primary path for the flow of a parenterally acceptable fluid therethrough; (b) a formulation chamber in the primary path, the formulation chamber comprising: (1) a wall surrounding a lumen; (2) an inlet for letting fluid from the primary path into the formulation chamber; (3) a beneficial agent in the formulation chamber that forms an agent formulation with fluid that enters the formulation chamber; (4) a film extended from the top to the bottom of the formulation chamber in the formulation chamber; said film separating said agent from the flow path and comprising releasing means that aids in controlling the rate of release of beneficial agent from the formulation chamber; (5) an outlet for letting an agent formulation leave the formulation chamber; (c) a secondary path for the flow of a parenterally acceptable fluid therethrough; (d) a formulation chamber in the secondary path, the formulation chamber comprising: (1) a wall surrounding a lumen; (2) an inlet for letting fluid from the secondary path into the formulation chamber; (3) a beneficial agent in the formulation chamber that forms an agent formulation with fluid that enters the formulation chamber; (4) a film extended from the top to the bottom of the formulation chamber in the formulation chamber, said film separating said agent from the flow path and comprising releasing means that aids in controlling the rate of release of beneficial agent from the formulation chamber; (5) an outlet for letting an agent formulation leave the formulation chamber; and, (e) a common path in communication with the primary path and in communication with the secondary path for receiving agent formulation, which common path when the system is in use is in communication with the animal for administering beneficial agent formulation thereto.
Claim 2
Dependent Claim 305 words
A parenteral delivery system for administering a beneficial agent formulation to an animal, the system comprising: (a) a primary path for the flow of a parenterally acceptable fluid therethrough; (b) a formulation chamber in the primary path, the formulation chamber comprising: (1) a wall surrounding a lumen; (2) an inlet for letting fluid from the primary path into the formulation chamber; (3) a beneficial agent in the formulation chamber that forms an agent formulation with fluid that enters the formulation chamber; (4) a film extended from the top to the bottom of the formulation chamber in the formulation chamber; said film separating said agent from the flow path and comprising releasing means that aids in controlling the rate of release of beneficial agent from the formulation chamber; (5) an outlet for letting an agent formulation leave the formulation chamber; (c) a secondary path for the flow of a parenterally acceptable fluid therethrough; (d) a formulation chamber in the secondary path, the formulation chamber comprising: (1) a wall surrounding a lumen; (2) an inlet for letting fluid from the secondary path into the formulation chamber; (3) a beneficial agent in the formulation chamber that forms an agent formulation with fluid that enters the formulation chamber; (4) a film extended from the top to the bottom of the formulation chamber in the formulation chamber, said film separating said agent from the flow path and comprising releasing means that aids in controlling the rate of release of beneficial agent from the formulation chamber; (5) an outlet for letting an agent formulation leave the formulation chamber; and, (e) a common path in communication with the primary path and in communication with the secondary path for receiving agent formulation, which common path when the system is in use is in communication with the animal for administering beneficial agent formulation thereto.
Claim 3
Dependent Claim 26 words
The parenteral delivery system for administering the beneficial agent formulation according to claim 1, wherein the beneficial agent is placed to the side of the film.
Claim 4
Dependent Claim 25 words
The parenteral delivery system for administering the beneficial agent formulation according to claim 1, wherein the formulation chamber is in communication with a drip chamber.
Claim 5
Dependent Claim 286 words
A parenteral delivery system for administering a beneficial agent formulation to an animal, the system comprising: (a) a primary path for the flow of a parenterally acceptable fluid therethrough; (b) a formulation chamber in the primary path, the formulation chamber comprising: (1) a wall surrounding a lumen; (2) an inlet for letting fluid from the primary path into the formulation chamber; (3) about 5 milligrams to 20 grams of a solid beneficial agent in the formulation chamber that forms an agent formulation with fluid that enters the formulation chamber; (4) a fluid permeable film in the formulation chamber to the side of the inlet that confines the beneficial agent therein, said film providing releasing means for said agent; (5) an outlet for letting an agent formulation leave the formulation chamber; (c) a secondary path for the flow of a parenterally acceptable fluid therethrough; (d) a formulation chamber in the secondary path, the formulation chamber comprising: (1) a wall surrounding a lumen; (2) an inlet for letting fluid from the secondary path into the formulation chamber; (3) about 5 milligrams to 20 grams of a solid beneficial agent in the formulation chamber that forms agent formulation with fluid that enters the formulation chamber; (4) a fluid permeable film in the formulation chamber to the side of the inlet that confines the beneficial agent therein, said film providing releasing means for said agent; (5) an outlet for letting an agent formulation leave the formulation chamber; and, (e) a common path in communication with the primary path and in communication with the secondary path for receiving agent formulation, which common path when the system is in use is in communication with the animal for administering beneficial agent formulation thereto.
Claim 6
Dependent Claim 286 words
A parenteral delivery system for administering a beneficial agent formulation to an animal, the system comprising: (a) a primary path for the flow of a parenterally acceptable fluid therethrough; (b) a formulation chamber in the primary path, the formulation chamber comprising: (1) a wall surrounding a lumen; (2) an inlet for letting fluid from the primary path into the formulation chamber; (3) about 5 milligrams to 20 grams of a solid beneficial agent in the formulation chamber that forms an agent formulation with fluid that enters the formulation chamber; (4) a fluid permeable film in the formulation chamber to the side of the inlet that confines the beneficial agent therein, said film providing releasing means for said agent; (5) an outlet for letting an agent formulation leave the formulation chamber; (c) a secondary path for the flow of a parenterally acceptable fluid therethrough; (d) a formulation chamber in the secondary path, the formulation chamber comprising: (1) a wall surrounding a lumen; (2) an inlet for letting fluid from the secondary path into the formulation chamber; (3) about 5 milligrams to 20 grams of a solid beneficial agent in the formulation chamber that forms agent formulation with fluid that enters the formulation chamber; (4) a fluid permeable film in the formulation chamber to the side of the inlet that confines the beneficial agent therein, said film providing releasing means for said agent; (5) an outlet for letting an agent formulation leave the formulation chamber; and, (e) a common path in communication with the primary path and in communication with the secondary path for receiving agent formulation, which common path when the system is in use is in communication with the animal for administering beneficial agent formulation thereto.
Claim 7
Dependent Claim 25 words
The parenteral delivery system for administering the beneficial agent formulation according to claim 4, wherein the formulation chamber is in communication with a drip chamber.
Claim 8
Dependent Claim 307 words
An intravenous delivery system for administering a beneficial drug formulation to an animal, the system comprising: (a) a primary path for the flow of an intravenously acceptable fluid therethrough; (b) a formulation chamber in the primary path, the formulation comprising: (1) a wall surrounding a lumen; (2) an inlet for letting fluid from the primary path into the formulation chamber; (3) about 5 milligrams to 20 grams of a solid, beneficial drug in the formulation chamber that forms a drug formulation with fluid that enters the formulation chamber; (4) a film in the formulation chamber that aids in governing the rate of release of drug formulation from the formulation chamber, said film releasing the beneficial drug formulation by microporous, diffusion or osmotic physical chemical mechanisms. (5) an outlet for letting an agent formulation leave the formulation chamber; (c) a secondary path for the flow of an intravenously acceptable fluid therethrough; (d) a formulation chamber in the secondary path, the formulation chamber comprising: (1) a wall surrounding a lumen; (2) an inlet for letting fluid from the secondary path into the formulation chamber; (3) about 5 milligrams to 20 grams of a solid beneficial drug in the formulation chamber that forms a drug formulation with fluid that enters the formulation chamber; (4) a film in the formulation chamber that aids in governing the rate of release of drug formulation from the formulation chamber, said film formed of a nontoxic material that releases the beneficial drug formulation by microporous, diffusion or osmotic physical-chemical mechanisms; (5) an outlet for letting an agent formulation leave the formulation chamber; and, (e) a common path in communication with the primary path and in communication with the secondary path for receiving drug formulation, which common path when the system is in use is in communication with the animal for administering beneficial drug formulation thereto.
Claim 9
Dependent Claim 307 words
An intravenous delivery system for administering a beneficial drug formulation to an animal, the system comprising: (a) a primary path for the flow of an intravenously acceptable fluid therethrough; (b) a formulation chamber in the primary path, the formulation comprising: (1) a wall surrounding a lumen; (2) an inlet for letting fluid from the primary path into the formulation chamber; (3) about 5 milligrams to 20 grams of a solid, beneficial drug in the formulation chamber that forms a drug formulation with fluid that enters the formulation chamber; (4) a film in the formulation chamber that aids in governing the rate of release of drug formulation from the formulation chamber, said film releasing the beneficial drug formulation by microporous, diffusion or osmotic physical chemical mechanisms. (5) an outlet for letting an agent formulation leave the formulation chamber; (c) a secondary path for the flow of an intravenously acceptable fluid therethrough; (d) a formulation chamber in the secondary path, the formulation chamber comprising: (1) a wall surrounding a lumen; (2) an inlet for letting fluid from the secondary path into the formulation chamber; (3) about 5 milligrams to 20 grams of a solid beneficial drug in the formulation chamber that forms a drug formulation with fluid that enters the formulation chamber; (4) a film in the formulation chamber that aids in governing the rate of release of drug formulation from the formulation chamber, said film formed of a nontoxic material that releases the beneficial drug formulation by microporous, diffusion or osmotic physical-chemical mechanisms; (5) an outlet for letting an agent formulation leave the formulation chamber; and, (e) a common path in communication with the primary path and in communication with the secondary path for receiving drug formulation, which common path when the system is in use is in communication with the animal for administering beneficial drug formulation thereto.
Claim 10
Dependent Claim 25 words
The intravenous delivery system for administering the beneficial drug formulation according to claim 6, wherein the formulation chamber is in communication with a drip chamber.

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1988-05-06 1988-11-05 1989-05-07 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1992-05-06 1992-11-05 1993-05-07 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1996-05-06 1996-11-05 1997-05-07 $7700.00 Window Closed / Lapsed

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