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Pyridinylimidazole pharmaceutical composition

Assignee: USV Pharmaceutical Corp
•
Filing: 1984-02-10
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Granted: 1985-04-09
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Expires: 2004-02-10
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Abstract

Abstract A pharmaceutical composition containing a therapeutically effective amount of a pyridinylimidazole 4- or 5-substituted carboxylic acid and esters thereof is provided to treat cardiovascular ailment.

Inventors

  • 👤 Thomas D. Lee

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-09 08:12
CPC Classifications
C; C07; C07D; C07D401/00; C07D401/02; C07D401/04

Claims Analysis

Total Claims: 6
Claim 1
Independent Claim 80 words
A pharmaceutical composition useful for treatment of congestive heart failure and hypertension comprising a pharmaceutically acceptable carrier and a therapeutically effective amount of a compound selected from the group consisting of pyridinylimidazoles of the formulae: ##STR3## and pharmaceutically acceptable acid addition salts thereof, wherein the imidazole radical is substituted on one of the R substituents and each of the remaining R substituents is hydrogen, R 1 is hydroxy, amino, methoxy or ethoxy, and R 2 is hydrogen, halo, or hydroxy.
Claim 2
Dependent Claim 80 words
A pharmaceutical composition useful for treatment of congestive heart failure and hypertension comprising a pharmaceutically acceptable carrier and a therapeutically effective amount of a compound selected from the group consisting of pyridinylimidazoles of the formulae: ##STR3## and pharmaceutically acceptable acid addition salts thereof, wherein the imidazole radical is substituted on one of the R substituents and each of the remaining R substituents is hydrogen, R 1 is hydroxy, amino, methoxy or ethoxy, and R 2 is hydrogen, halo, or hydroxy.
Claim 3
Dependent Claim 13 words
The composition of claim 1 wherein the pyridinylimidazole is 4(5)-(4'-pyridinyl)imidazole-5(4)-carboxylic acid ethyl ester.
Claim 4
Dependent Claim 13 words
The composition of claim 1 wherein the pyridinylimidazole is 4(5)-(4'-pyridinyl)imidazole-5(4)-carboyxlic acid methyl ester.
Claim 5
Dependent Claim 13 words
The pharmaceutical composition of claim 1 in the form of an oral composition.
Claim 6
Dependent Claim 13 words
The pharmaceutical composition of claim 1 in the form of an intravenous composition.

References Cited (Backward Citations)

US4302464A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1988-04-08 1988-10-08 1989-04-09 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1992-04-08 1992-10-08 1993-04-09 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1996-04-08 1996-10-08 1997-04-09 $7700.00 Window Closed / Lapsed

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