US4302464A
Expired / Lapsed
US
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Imidazolylpyridine therapeutic agents
Assignee: Pfizer Inc
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Filing: 1980-10-16
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Granted: 1981-11-24
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Expires: 2000-10-16
Abstract
Abstract A series of 2-substituted-4-(4-imidazolyl)pyridines and the pharmaceutically acceptable acid addition salts thereof as histamine H2-receptor inhibitors for controlling gastric acidity.
Inventors
- 👤 John L. LaMattina
- 👤 Christopher A. Lipinski
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-09 08:01
CPC Classifications
C; C07; C07D; C07D401/00; C07D401/02; C07D401/04; C07D213/00; C07D213/02; C07D213/04; C07D213/24; C07D213/44; C07D213/53; A; A61; A61P; A61P1/00; A61P1/04; C07D213/46; C07D213/51; C07D213/60; C07D213/61; C07D213/72; C07D213/73; C07D213/74; C07D213/78; C07D213/84
Claims Analysis
Total Claims: 15
Claim 1
Independent Claim
87 words
A compound selected from the group consisting of pyridylimidazoles of the formulae: ##STR7## and the pharmaceutically acceptable acid addition salts thereof, wherein R 1 is selected from the group consisting of hydrogen, alkyl having one to three carbon atoms and amino; R 2 and R 3 are each selected from the group consisting of hydrogen, alkyl having one to three carbon atoms and phenylalkyl wherein said alkyl contains from one to three carbon atoms; and R 4 is selected from the group consisting of methyl and amino.
Claim 2
Dependent Claim
87 words
A compound selected from the group consisting of pyridylimidazoles of the formulae: ##STR7## and the pharmaceutically acceptable acid addition salts thereof, wherein R 1 is selected from the group consisting of hydrogen, alkyl having one to three carbon atoms and amino; R 2 and R 3 are each selected from the group consisting of hydrogen, alkyl having one to three carbon atoms and phenylalkyl wherein said alkyl contains from one to three carbon atoms; and R 4 is selected from the group consisting of methyl and amino.
Claim 3
Dependent Claim
24 words
A compound of claim 1, formula I, wherein R 2 is hydrogen and R 3 is alkyl having from one to three carbon atoms.
Claim 4
Dependent Claim
15 words
The compound of claim 2 wherein R 1 is amino and R 3 is ethyl.
Claim 5
Dependent Claim
15 words
The compound of claim 2 wherein R 1 is hydrogen and R 3 is ethyl.
Claim 6
Dependent Claim
15 words
The compound of claim 2 wherein R 1 is methyl and R 3 is ethyl.
Claim 7
Dependent Claim
14 words
The compound of claim 2 wherein R 1 and R 3 are each ethyl.
Claim 8
Dependent Claim
23 words
A compound of claim 1, formula I, wherein R 2 and R 3 are each alkyl having from one to three carbon atoms.
Claim 9
Dependent Claim
19 words
The compound of claim 7 wherein R 1 is hydrogen and R 2 and R 3 are each methyl.
Claim 10
Dependent Claim
20 words
The compound of claim 7 wherein R 1 is amino and R 2 and R 3 l are each methyl.
Claim 11
Dependent Claim
16 words
A compound of claim 1, formula I, wherein R 2 and R 3 are each hydrogen.
Claim 12
Dependent Claim
10 words
The compound of claim 10 wherein R 1 is hydrogen.
Claim 13
Dependent Claim
12 words
The compound of claim 1, formula II, wherein R 4 is methyl.
Claim 14
Dependent Claim
12 words
The compound of claim 1, formula II, wherein R 4 is amino.
Claim 15
Dependent Claim
31 words
A pharmaceutical composition suitable for oral administration comprising a pharmaceutically acceptable carrier and a therapeutically-effective amount of an anti-ulcer agent wherein said agent is a compound as claimed in claim 1.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1984-11-23 | 1985-05-25 | 1985-11-24 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1988-11-23 | 1989-05-25 | 1989-11-24 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1992-11-23 | 1993-05-25 | 1993-11-24 | $7700.00 | Window Closed / Lapsed |