US4492685A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Protective skin matrix
Assignee: Key Pharmaceuticals Inc
•
Filing: 1984-01-30
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Granted: 1985-01-08
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Expires: 2004-01-30
Abstract
Abstract A protective skin matrix is provided which is particularly suited for the protection of burned or wounded patients. The matrix may be either cured, applied in sheets, or painted or sprayed directly onto the burned or wounded patient. The protective skin matrix includes polyvinylpyrrolidone, polyvinylalcohol, and glycerol.
Inventors
- 👤 Alec D. Keith
- 👤 Wallace Snipes
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-25 01:25
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/70; A61K9/7023; A61K9/703; A61K9/7084; A61K31/00; A61K31/13; A61K31/135; A61K31/33; A61K31/395; A61K31/41; A61K31/415; A61K31/56; A61K31/565
Claims Analysis
Total Claims: 11
Claim 1
Independent Claim
120 words
A cured self-supporting polymeric diffusion matrix suitable for providing protection to a burned or wounded patient, said matrix being formed by: (a) heating an aqueous system comprising 2 to 20% glycerol, 4 to 30% polyvinyl alcohol molecular weight 50,000 to 150,000, 2 to 20% polyvinylpyrrolidone molecular weight 25,000 to 100,000, and the balance water, the weight ratio of polyvinyl alcohol to polyvinylpyrrolidone being 2:1 to 3:2, the weight ratio of glycerol to polyvinyl alcohol and polyvinylpyrrolidone together being 0.5:1 to 1:1, and weight ratio of water to glycerol being 3:1 to 7:1, until solution occurs, (b) casting or molding the resultant solution, and (c) curing the cast or molded solution by permitting it to stand for one-half to twenty-four hours.
Claim 2
Dependent Claim
120 words
A cured self-supporting polymeric diffusion matrix suitable for providing protection to a burned or wounded patient, said matrix being formed by: (a) heating an aqueous system comprising 2 to 20% glycerol, 4 to 30% polyvinyl alcohol molecular weight 50,000 to 150,000, 2 to 20% polyvinylpyrrolidone molecular weight 25,000 to 100,000, and the balance water, the weight ratio of polyvinyl alcohol to polyvinylpyrrolidone being 2:1 to 3:2, the weight ratio of glycerol to polyvinyl alcohol and polyvinylpyrrolidone together being 0.5:1 to 1:1, and weight ratio of water to glycerol being 3:1 to 7:1, until solution occurs, (b) casting or molding the resultant solution, and (c) curing the cast or molded solution by permitting it to stand for one-half to twenty-four hours.
Claim 3
Independent Claim
139 words
A method of protecting a burned or wounded area of a patient over a prolonged period of time, which comprises placing over said burned or wounded area of said patient a cured polymeric diffusion matrix, said matrix being formed by: (a) heating an aqueous system comprising 2 to 20% glycerol, 4 to 30% polyvinyl alcohol molecular weight 50,000 to 150,000, 2 to 20% polyvinylpyrrolidone molecular weight 25,000 to 100,000, and the balance water, the weight ratio of polyvinyl alcohol to polyvinylpyrrolidone being 2:1 to 3:2, the weight ratio of glycerol to polyvinyl alcohol and polyvinylpyrrolidone together being 0.5:1 to 1:1, and weight ratio of water to glycerol being 3:1 to 7:1, until solution occurs, (b) casting or molding the resultant solution, and (c) curing the cast or molded solution by permitting it to stand for one-half to twenty-four hours.
Claim 4
Independent Claim
139 words
A method of protecting a burned or wounded area of a patient over a prolonged period of time, which comprises placing over said burned or wounded area of said patient a cured polymeric diffusion matrix, said matrix being formed by: (a) heating an aqueous system comprising 2 to 20% glycerol, 4 to 30% polyvinyl alcohol molecular weight 50,000 to 150,000, 2 to 20% polyvinylpyrrolidone molecular weight 25,000 to 100,000, and the balance water, the weight ratio of polyvinyl alcohol to polyvinylpyrrolidone being 2:1 to 3:2, the weight ratio of glycerol to polyvinyl alcohol and polyvinylpyrrolidone together being 0.5:1 to 1:1, and weight ratio of water to glycerol being 3:1 to 7:1, until solution occurs, (b) casting or molding the resultant solution, and (c) curing the cast or molded solution by permitting it to stand for one-half to twenty-four hours.
Claim 5
Dependent Claim
32 words
The polymeric diffusion matrix of claim 1 further comprising a drug and wherein said drug is an antibiotic, an antiseptic, a local anesthetic, an analgesic, a fungicide, a bactericide, or an anti-micoplasma.
Claim 6
Dependent Claim
32 words
The method of claim 2 wherein said matrix also contains a drug and said drug is an antibiotic, an antiseptic, a local anesthetic, an analgesic, a fungicide, a bactericide, or an anti-micoplasma.
Claim 7
Dependent Claim
11 words
The method of claim 4 wherein said drug is an antiseptic.
Claim 8
Dependent Claim
11 words
The method of claim 5 wherein said drug is an antibiotic.
Claim 9
Dependent Claim
17 words
The method of claim 6 wherein said drug comprises a mixture of an antiseptic and an antibiotic.
Claim 10
Dependent Claim
13 words
The polymeric diffusion matrix of claim 3 wherein said drug is an antiseptic.
Claim 11
Dependent Claim
13 words
The polymeric diffusion matrix of claim 3 wherein said drug is an antibiotic.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1988-01-08 | 1988-07-09 | 1989-01-08 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1992-01-08 | 1992-07-09 | 1993-01-08 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1996-01-08 | 1996-07-09 | 1997-01-08 | $7700.00 | Window Closed / Lapsed |