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US4486418A
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2'-Deamino aminoglycosides and composition thereof
Assignee: Kowa Co Ltd
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Filing: 1983-06-06
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Granted: 1984-12-04
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Expires: 2003-06-06
Abstract
Abstract An aminoglycoside represented by the following formula (1) <IMAGE> (1) wherein each of R1 and R2 represents a hydrogen atom or a methyl group, R3 represents a hydrogen atom or an aminoacyl group, R4 represents a hydrogen atom or a hydroxyl or methoxy group, and R5 represents a hydrogen atom or a hydroxyl group, or a pharmaceutically acceptable acid addition salt thereof, a process for the production thereof and a pharmaceutical use thereof.
Inventors
- 👤 Isamu Watanabe
- 👤 Takashi Yamaguchi
- 👤 Kazuhiro Kamiya
- 👤 Toshihito Mori
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-07 14:37
CPC Classifications
C; C07; C07H; C07H15/00; C07H15/20; C07H15/22; C07H15/222; C07H15/224; A; A61; A61P; A61P31/00; A61P31/04; C07D; C07D309/00; C07D309/02; C07D309/08; C07D309/10
Claims Analysis
Total Claims: 5
Claim 1
Independent Claim
76 words
An aminoglycoside represented by the following formula (1) ##STR24## wherein each of R 1 and R 2 represents a hydrogen atom or a methyl group, R 3 represents a hydrogen atom or an aminoacyl group having 2 to 4 carbon atoms in the acyl group, R 4 represents a hydrogen atom or a hydroxyl or methoxy group, and R 5 represents a hydrogen atom or a hydroxyl group, or a pharmaceutically acceptable acid addition salt thereof.
Claim 2
Dependent Claim
76 words
An aminoglycoside represented by the following formula (1) ##STR24## wherein each of R 1 and R 2 represents a hydrogen atom or a methyl group, R 3 represents a hydrogen atom or an aminoacyl group having 2 to 4 carbon atoms in the acyl group, R 4 represents a hydrogen atom or a hydroxyl or methoxy group, and R 5 represents a hydrogen atom or a hydroxyl group, or a pharmaceutically acceptable acid addition salt thereof.
Claim 3
Dependent Claim
94 words
An antibiotic composition which comprises (i) an antibiotically effective amount of a compound having the following formula (1) ##STR25## wherein each of R 1 and R 2 represents a hydrogen atom or a methyl group, R 3 represents a hydrogen atom or an aminoacyl group having 2 to 4 carbon atoms in the acyl group, R 4 represents a hydrogen atom or a hydroxyl or methoxy group, and R 5 represents a hydrogen atom or a hydroxyl group, or a pharmaceutically acceptable acid addition salt thereof, and (ii) a pharmaceutically acceptable diluent or carrier.
Claim 4
Dependent Claim
94 words
An antibiotic composition which comprises (i) an antibiotically effective amount of a compound having the following formula (1) ##STR25## wherein each of R 1 and R 2 represents a hydrogen atom or a methyl group, R 3 represents a hydrogen atom or an aminoacyl group having 2 to 4 carbon atoms in the acyl group, R 4 represents a hydrogen atom or a hydroxyl or methoxy group, and R 5 represents a hydrogen atom or a hydroxyl group, or a pharmaceutically acceptable acid addition salt thereof, and (ii) a pharmaceutically acceptable diluent or carrier.
Claim 5
Dependent Claim
37 words
The antibiotic composition of claim 2 wherein the amount of the compound of formula (1) or its pharmaceutically acceptable acid addition salt is about 0.01 to about 99.5% by weight based on the weight of the composition.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1987-12-04 | 1988-06-04 | 1988-12-04 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1991-12-04 | 1992-06-04 | 1992-12-04 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1995-12-04 | 1996-06-04 | 1996-12-04 | $7700.00 | Window Closed / Lapsed |