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US4484909A Expired / Lapsed US ⏱️ 0.0 years remaining

Parenteral therapy using solid drug

Assignee: Alza Corp
•
Filing: 1983-10-17
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Granted: 1984-11-27
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Expires: 2003-10-17
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Abstract

Abstract A parenteral delivery set is disclosed for administering a beneficial agent to a recipient. The set comprises (a) a primary container of a medical fluid; (b) a primary tubing in fluid communication with the primary container; (c) a secondary container of a medical fluid; (d) a secondary tubing in fluid communication with the secondary container; (e) a formulation chamber connected to the secondary tubing and housing an agent dispensing device or the beneficial agent; and (f) a common tubing in communication with the primary tubing and the secondary tubing for communicating the set to the recipient.

Inventors

  • 👤 John Urquhart
  • 👤 Felix Theeuwes

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 21:59
CPC Classifications
A; A61; A61M; A61M5/00; A61M5/14; A61M5/1407; A61M5/142; A61M5/145; A61M2005/14513

Claims Analysis

Total Claims: 11
Claim 1
Independent Claim 227 words
A parenteral delivery set for the administration of a beneficial drug formulation, the delivery set comprising: (a) a primary tube for the flow of a parenterally acceptable fluid therethrough; (b) a secondary tube for the flow of a parenterally acceptable fluid therethrough; (c) a formulation chamber having means for communicating with the secondary tube, the formulation chamber comprising: (1) a wall that surrounds an internal lumen; (2) an inlet in the wall adapted for letting a parenterally acceptable fluid into the formulation chamber; (3) a beneficial drug in solid dosage form presented in the formulation chamber in a therapeutically effective amount for executing a prescribed therapeutic program, which drug, when the delivery set is in use, is formulated with parenterally acceptable fluid that flows into the formulation chamber, which fluid is a pharmaceutically acceptable carrier for the drug and forms with the drug a formulation acceptable for parenteral administration; (4) an outlet in the wall for letting drug formulation leave the formulation chamber; (5) a film in the formulation chamber positioned between the drug and the outlet, said film formed of a polymeric composition that releases drug formulation from the formulation chamber; and, (d) a common tub having means for communicating with the primary tube for receiving fluid from the primary tube, and for communicating with the formulation chamber for receiving drug formulation from the formulation chamber.
Claim 2
Dependent Claim 227 words
A parenteral delivery set for the administration of a beneficial drug formulation, the delivery set comprising: (a) a primary tube for the flow of a parenterally acceptable fluid therethrough; (b) a secondary tube for the flow of a parenterally acceptable fluid therethrough; (c) a formulation chamber having means for communicating with the secondary tube, the formulation chamber comprising: (1) a wall that surrounds an internal lumen; (2) an inlet in the wall adapted for letting a parenterally acceptable fluid into the formulation chamber; (3) a beneficial drug in solid dosage form presented in the formulation chamber in a therapeutically effective amount for executing a prescribed therapeutic program, which drug, when the delivery set is in use, is formulated with parenterally acceptable fluid that flows into the formulation chamber, which fluid is a pharmaceutically acceptable carrier for the drug and forms with the drug a formulation acceptable for parenteral administration; (4) an outlet in the wall for letting drug formulation leave the formulation chamber; (5) a film in the formulation chamber positioned between the drug and the outlet, said film formed of a polymeric composition that releases drug formulation from the formulation chamber; and, (d) a common tub having means for communicating with the primary tube for receiving fluid from the primary tube, and for communicating with the formulation chamber for receiving drug formulation from the formulation chamber.
Claim 3
Dependent Claim 30 words
The parenteral delivery set for the administration of the beneficial drug according to claim 1 wherein the secondary tube is in communication with the formulation chamber and the common tube.
Claim 4
Dependent Claim 26 words
The parenteral delivery set for the administration of the beneficial drug according to claim 1 wherein the formulation chamber is in communication with a drip chamber.
Claim 5
Dependent Claim 36 words
The parenteral delivery set for the administration of the beneficial drug according to claim 1 wherein the concentration of the drug administered is controlled by adjusting the rate of flow of fluid through the secondary path.
Claim 6
Dependent Claim 49 words
The parenteral delivery set for the administration of the beneficial drug according to claim 1 wherein the concentration of the drug administered is controlled by adjusting the rate of flow of fluid through the primary path and by adjusting the rate of flow of fluid through the secondary path.
Claim 7
Dependent Claim 27 words
The parenteral delivery set for the administration of the beneficial drug according to claim 1, wherein the film between the drug and the outlet surrounds the drug.
Claim 8
Dependent Claim 215 words
A parenteral delivery set for the administration of a beneficial drug formulation, the delivery set comprising: (a) a primary tube for the flow of a parenterally acceptable fluid; (b) a secondary tube for the flow of a parenterally acceptable fluid; (c) a formulation chamber having means for communicating with the secondary tube, the formulation chamber comprising: (1) a wall that surrounds an internal lumen; (2) an inlet in the wall for letting a parenterally acceptable fluid into the formulation chamber; (3) a beneficial drug in solid dosage form present in the formulation chamber in a therapeutically effective amount for executing a therapeutic program; which drug, when the delivery set is in use, is formulated with parenterally acceptable fluid that flows into the formulation chamber, which fluid is a pharmaceutically acceptable carrier for the drug and forms with the drug a formulation acceptable for parenteral administration; (4) an outlet in the wall for letting drug formulation leave the formulation chamber; (5) a film placed vertically in the formulation chamber to the side of the inlet and outlet ports confining drug therein, said film formed of a polymeric composition that releases drug formulation from the formulation chamber; and, (d) a common tube having means for communicating with the primary tube, and for communicating with the formulation chamber.
Claim 9
Dependent Claim 215 words
A parenteral delivery set for the administration of a beneficial drug formulation, the delivery set comprising: (a) a primary tube for the flow of a parenterally acceptable fluid; (b) a secondary tube for the flow of a parenterally acceptable fluid; (c) a formulation chamber having means for communicating with the secondary tube, the formulation chamber comprising: (1) a wall that surrounds an internal lumen; (2) an inlet in the wall for letting a parenterally acceptable fluid into the formulation chamber; (3) a beneficial drug in solid dosage form present in the formulation chamber in a therapeutically effective amount for executing a therapeutic program; which drug, when the delivery set is in use, is formulated with parenterally acceptable fluid that flows into the formulation chamber, which fluid is a pharmaceutically acceptable carrier for the drug and forms with the drug a formulation acceptable for parenteral administration; (4) an outlet in the wall for letting drug formulation leave the formulation chamber; (5) a film placed vertically in the formulation chamber to the side of the inlet and outlet ports confining drug therein, said film formed of a polymeric composition that releases drug formulation from the formulation chamber; and, (d) a common tube having means for communicating with the primary tube, and for communicating with the formulation chamber.
Claim 10
Dependent Claim 29 words
The parenteral delivery set for the administration of the beneficial drug according to claim 7 wherein the secondary tube is in communication with the outlet of the formulation chamber.
Claim 11
Dependent Claim 26 words
The parenteral delivery set for the administration of the beneficial drug according to claim 7 wherein the formulation chamber is in communication with a drip chamber.

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1987-11-27 1988-05-28 1988-11-27 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1991-11-27 1992-05-28 1992-11-27 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1995-11-27 1996-05-28 1996-11-27 $7700.00 Window Closed / Lapsed

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