Patent US4439183A successfully refreshed from Google Patents.
US4439183A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Parenteral agent dispensing equipment
Assignee: Alza Corp
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Filing: 1982-05-13
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Granted: 1984-03-27
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Expires: 2002-05-13
Abstract
Abstract A parenteral delivery system and a formulation chamber are disclosed for administering a beneficial agent. The parenteral delivery system comprises a drip chamber and a formulation chamber. The formulation chamber comprises a wall surrounding an internal space and it has an inlet for admitting a liquid into the formulation chamber and an outlet for letting an agent formulation leave the formulation chamber. The chamber houses an agent delivery system for releasing a beneficial agent into a liquid that enters the chamber.
Inventors
- 👤 Felix Theeuwes
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-25 23:35
CPC Classifications
A; A61; A61M; A61M5/00; A61M5/14; A61M5/1407
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
92 words
A formulation chamber for use in a parenteral delivery system, comprising: (a) a wall surrounding an internal lumen; (b) an inlet for admitting a fluid into the chamber; (c) an outlet for letting a fluid leave the chamber; and, (d) an erodible delivery system in the chamber, comprising: (1) a matrix formed of a parenterally-acceptable material that erodes in the presence of a parenteral fluid over time, and; (2) a beneficial agent dispersed in the matrix that is delivered by the erodible delivery system into parenteral fluid that enters the formulation chamber.
Claim 2
Dependent Claim
92 words
A formulation chamber for use in a parenteral delivery system, comprising: (a) a wall surrounding an internal lumen; (b) an inlet for admitting a fluid into the chamber; (c) an outlet for letting a fluid leave the chamber; and, (d) an erodible delivery system in the chamber, comprising: (1) a matrix formed of a parenterally-acceptable material that erodes in the presence of a parenteral fluid over time, and; (2) a beneficial agent dispersed in the matrix that is delivered by the erodible delivery system into parenteral fluid that enters the formulation chamber.
Claim 3
Dependent Claim
35 words
The formulation chamber for use in a parenteral delivery system according to claim 1, wherein the chamber contains a separate film that aids in controlling the rate of release of agent formulation from the chamber.
Claim 4
Dependent Claim
36 words
The formulation chamber for use in a parenteral delivery system according to claim 1, wherein the chamber contains a separate porous film that aids in controlling the rate of release of agent formulation from the chamber.
Claim 5
Dependent Claim
29 words
The formulation chamber for use in a parenteral delivery system according to claim 1, wherein the chamber contains a perforated grid that supports erodible delivery system in the chamber.
Claim 6
Dependent Claim
30 words
The formulation chamber for use in a parenteral delivery system according to claim 1, wherein the parenteral delivery system comprises a drip chamber in fluid communication with the formulation chamber.
Claim 7
Dependent Claim
132 words
An intravenous delivery system for administering a beneficial agent intravenously to a human, comprising: (a) a container of a pharmaceutically acceptable liquid; (b) a drip chamber in fluid communication with the container for determining the rate of fluid flow through the intravenous system for the continuous drip administration of liquid; and, (c) a formulation comprising: (1) a wall surrounding a lumen; (2) an erodible agent delivery system in the chamber comprising a matrix formed of a polymer containing agent dispersed therein, which matrix erodes in the presence of a pharmaceutically acceptable liquid that enters the formulation chamber; and, (3) wherein the formulation chamber is in fluid communication with the drip chamber such that liquid flows into the formulation chamber and forms with agent released from the matrix an agent formulation over time.
Claim 8
Dependent Claim
132 words
An intravenous delivery system for administering a beneficial agent intravenously to a human, comprising: (a) a container of a pharmaceutically acceptable liquid; (b) a drip chamber in fluid communication with the container for determining the rate of fluid flow through the intravenous system for the continuous drip administration of liquid; and, (c) a formulation comprising: (1) a wall surrounding a lumen; (2) an erodible agent delivery system in the chamber comprising a matrix formed of a polymer containing agent dispersed therein, which matrix erodes in the presence of a pharmaceutically acceptable liquid that enters the formulation chamber; and, (3) wherein the formulation chamber is in fluid communication with the drip chamber such that liquid flows into the formulation chamber and forms with agent released from the matrix an agent formulation over time.
References Cited (Backward Citations)
US25129A
Cited
USRE25129E
Cited
US3001525A
Cited
US3625214A
Cited
US3847150A
Cited
US3941126A
Cited
US3976068A
Cited
US4203439A
Cited
US4217894A
Cited
US4290426A
Cited
US4233973A
Cited
US4235236A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1987-03-27 | 1987-09-26 | 1988-03-27 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1991-03-27 | 1991-09-26 | 1992-03-27 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1995-03-27 | 1995-09-26 | 1996-03-27 | $7700.00 | Window Closed / Lapsed |