← Back to Patent Explorer
US4436721A Expired / Lapsed US ⏱️ 0.0 years remaining

Oral composition having mole ratio of tetra (methylene phosphonate) to alkali metal fluoride of at least 1.4:1

Assignee: Colgate Palmolive Co
•
Filing: 1983-06-08
•
Granted: 1984-03-13
•
Expires: 2003-06-08
📄 Original PDF 🌐 Google Patents 🔄 Sync Now

Abstract

Abstract Anti-caries, anti-calculus oral composition, such as dental cream or gel or mouthwash, containing a diamine tetra (methylene phosphonic acid) salt, such as ethylene diamine tetra (methylene polyphosphonic acid) salt, and alkali metal fluoride, such as sodium fluoride. The mole ratio of the tetra (methylene phosphonate) portion to fluoride is at least 1.4:1, thereby providing optimum anti-caries and anti-calculus effects.

Inventors

  • 👤 Abdul Gaffar

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-26 18:44
CPC Classifications
A; A61; A61K; A61K8/00; A61K8/18; A61K8/30; A61K8/55; A61K8/19; A61K8/20; A61K8/21; A61K8/69; A61Q; A61Q11/00

Claims Analysis

Total Claims: 9
Claim 1
Independent Claim 101 words
An oral composition comprising an oral vehicle, at least about 0.275% by weight of a diamine tetra (methylene phosphonate) having the formula: ##STR2## wherein n is a number from 1 to 10 and X is selected from the group consisting of hydrogen and an orally acceptable cation, at least one X group being an orally acceptable cation, and alkali metal fluoride, in amount which provides about 0.01-1% by weight of fluoride ion, the mole ratio of the tetra (methylene phosphonate) portion, (CH 2 -PO 3 -2 )4, of said diamine tetra (methylene phosphonate) to fluoride ion being at least about 1.4:1.
Claim 2
Dependent Claim 101 words
An oral composition comprising an oral vehicle, at least about 0.275% by weight of a diamine tetra (methylene phosphonate) having the formula: ##STR2## wherein n is a number from 1 to 10 and X is selected from the group consisting of hydrogen and an orally acceptable cation, at least one X group being an orally acceptable cation, and alkali metal fluoride, in amount which provides about 0.01-1% by weight of fluoride ion, the mole ratio of the tetra (methylene phosphonate) portion, (CH 2 -PO 3 -2 )4, of said diamine tetra (methylene phosphonate) to fluoride ion being at least about 1.4:1.
Claim 3
Dependent Claim 29 words
The oral composition claimed in claim 1 wherein said diamine tetra (methylene phosphonate) is ethylene diamine tetra (methylenephosphonic acid) sodium salt and said alkali metal fluoride is sodium fluoride.
Claim 4
Dependent Claim 22 words
The oral composition claimed in claim 1 wherein said diamine tetra (methylene phosphonate) is present in amount of about 0.275-5.5% by weight.
Claim 5
Dependent Claim 27 words
The oral composition claimed in claim 1 wherein said alkali metal fluoride is sodium fluoride, which sodium fluoride is present in amount of about 0.1-0.32% by weight.
Claim 6
Dependent Claim 27 words
The oral composition claimed in claim 1 wherein the mole ratio of said diamine tetra (methylene phosphonate) to fluoride ion is from about 1.4:1 to about 3.2:1.
Claim 7
Dependent Claim 32 words
The oral composition claimed in claim 1 wherein about 15-75% by weight of an orally acceptable dental polishing material is present and said composition is a toothpaste or dental cream or gel.
Claim 8
Dependent Claim 16 words
The oral composition claimed in claim 6 wherein said polishing material is a siliceous polishing agent.
Claim 9
Dependent Claim 25 words
The oral composition claimed in claim 1 wherein said oral vehicle contains a mixture of water and non-toxic alcohol and said composition is a mouthwash.

References Cited (Backward Citations)

DE2224516A1 Cited
US4137303A Cited
US4143128A Cited
US4177258A Cited
US4183915A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1987-03-13 1987-09-12 1988-03-13 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1991-03-13 1991-09-12 1992-03-13 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1995-03-13 1995-09-12 1996-03-13 $7700.00 Window Closed / Lapsed

Assigned Categories & Tags

No categories assigned to this patent yet.

Assign Category Tag