US4143128A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Oral compositions for calculus retardation
Assignee: Colgate Palmolive Co
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Filing: 1977-06-10
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Granted: 1979-03-06
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Expires: 1997-06-10
Abstract
Abstract Oral compositions, such as foods, toothpaste, mouthwash, and the like, containing certain polyamine polyphosphonates as herein defined which retard dental calculus formation without damaging tooth structure.
Inventors
- 👤 Keun Y. Kim
- 👤 Marvin M. Crutchfield
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-27 15:35
CPC Classifications
A; A61; A61K; A61K8/00; A61K8/18; A61K8/30; A61K8/55; A61Q; A61Q11/00
Claims Analysis
Total Claims: 18
Claim 1
Independent Claim
117 words
An oral mouthwash or toothpaste composition effective in inhibiting the formation of dental calculus without adversely affecting tooth structure comprising (1) a dental calculus inhibiting amount of at least about 0.01% of a polyamine polyphosphonate selected from the group consisting of those of the formula: ##STR2## wherein n is a number from 1 to 10, or a pharmaceutically acceptable water soluble salt thereof; and (2) a paste or flavored mouthwash carrier suitable for use in the oral cavity, the pH of the oral composition being within the range of from about 5.0 to about 11.0, said composition being free of calcium abrasives which would yield enough soluble calcium to significantly impair the anticalculus activity of said polyphosphonate.
Claim 2
Dependent Claim
117 words
An oral mouthwash or toothpaste composition effective in inhibiting the formation of dental calculus without adversely affecting tooth structure comprising (1) a dental calculus inhibiting amount of at least about 0.01% of a polyamine polyphosphonate selected from the group consisting of those of the formula: ##STR2## wherein n is a number from 1 to 10, or a pharmaceutically acceptable water soluble salt thereof; and (2) a paste or flavored mouthwash carrier suitable for use in the oral cavity, the pH of the oral composition being within the range of from about 5.0 to about 11.0, said composition being free of calcium abrasives which would yield enough soluble calcium to significantly impair the anticalculus activity of said polyphosphonate.
Claim 3
Dependent Claim
99 words
An oral mouthwash or toothpaste composition effective in inhibiting the formation of dental calculus without adversely affecting tooth structure comprising (1) a dental calculus inhibiting amount of at least about 0.01% of hexamethylene diamine tetra(methylene phosphonic acid) or a pharmaceutically acceptable water soluble salt thereof and (2) a toothpaste or flavored mouthwash carrier suitable for use in the oral cavity, the pH of the oral composition being within the range of from about 5.0 to about 10,0, said composition being free of calcium abrasives which would yield enough soluble calcium to significantly impair the anticalculus activity of said polyphosphonate.
Claim 4
Dependent Claim
99 words
An oral mouthwash or toothpaste composition effective in inhibiting the formation of dental calculus without adversely affecting tooth structure comprising (1) a dental calculus inhibiting amount of at least about 0.01% of hexamethylene diamine tetra(methylene phosphonic acid) or a pharmaceutically acceptable water soluble salt thereof and (2) a toothpaste or flavored mouthwash carrier suitable for use in the oral cavity, the pH of the oral composition being within the range of from about 5.0 to about 10,0, said composition being free of calcium abrasives which would yield enough soluble calcium to significantly impair the anticalculus activity of said polyphosphonate.
Claim 5
Dependent Claim
99 words
An oral mouthwath or toothpaste composition effective in inhibiting the formation of dental calculus without adversely affecting tooth structure comprising (1) a dental calculus inhibiting amount of at least about 0.01% of ethylene diamine tetra(methylene phosphonic acid) or a pharmaceutically acceptable water soluble salt thereof; and (2) a toothpaste or flavored mouthwash carrier suitable for use in the oral cavity, the pH of the oral composition being within the range of from about 5.0 to about 11.0, said composition being free of calcium abrasives which would yield enough soluble calcium to significantly impair the anti-calculus activity of said polyphosphonate.
Claim 6
Dependent Claim
99 words
An oral mouthwath or toothpaste composition effective in inhibiting the formation of dental calculus without adversely affecting tooth structure comprising (1) a dental calculus inhibiting amount of at least about 0.01% of ethylene diamine tetra(methylene phosphonic acid) or a pharmaceutically acceptable water soluble salt thereof; and (2) a toothpaste or flavored mouthwash carrier suitable for use in the oral cavity, the pH of the oral composition being within the range of from about 5.0 to about 11.0, said composition being free of calcium abrasives which would yield enough soluble calcium to significantly impair the anti-calculus activity of said polyphosphonate.
Claim 7
Dependent Claim
23 words
A composition of claim 1 wherein the polyamine polyphosphonate is tetramethylene diamine tetra(methylene phosphonic acid) or a pharmaceutically acceptable water soluble salt thereof.
Claim 8
Dependent Claim
14 words
A composition of claim 1 wherein said oral composition is an oral hygiene product.
Claim 9
Dependent Claim
13 words
A composition according to claim 5 wherein said oral composition is a toothpaste.
Claim 10
Dependent Claim
13 words
A composition according to claim 5 wherein said oral composition is a mouthwash.
Claim 11
Dependent Claim
15 words
A composition according to claim 2 wherein said oral composition is an oral hygiene product.
Claim 12
Dependent Claim
13 words
A composition according to claim 8 wherein said oral composition is a toothpaste.
Claim 13
Dependent Claim
13 words
A composition according to claim 8 wherein said oral composition is a mouthwash.
Claim 14
Dependent Claim
15 words
A composition according to claim 3 wherein said oral composition is an oral hygiene product.
Claim 15
Dependent Claim
13 words
A composition according to claim 10 wherein said oral composition is a toothpaste.
Claim 16
Dependent Claim
13 words
A composition according to claim 10 wherein said oral composition is a mouthwash.
Claim 17
Dependent Claim
116 words
An oral mouthwash or toothpaste composition effective in inhibiting the formation of dental calculus without adversely tooth structure comprising (1) a dental calculus inhibiting amount of at least about 0.01% of a polyamine polyphosphonate selected from the group consisting of those of the formula: ##STR3## wherein n is a number from 2 to 6, or a pharmaceutically acceptable water soluble salt thereof; and (2) a toothpaste or aqueous-alcohol mouthwash carrier suitable for use in the oral cavity, the pH of the oral composition being within the range of from about 5.0 to about 11.0, said composition being free of calcium abrasives which would yield enough soluble calcium to significantly impair the anticalculus activity of said polyphosphonate.
Claim 18
Dependent Claim
116 words
An oral mouthwash or toothpaste composition effective in inhibiting the formation of dental calculus without adversely tooth structure comprising (1) a dental calculus inhibiting amount of at least about 0.01% of a polyamine polyphosphonate selected from the group consisting of those of the formula: ##STR3## wherein n is a number from 2 to 6, or a pharmaceutically acceptable water soluble salt thereof; and (2) a toothpaste or aqueous-alcohol mouthwash carrier suitable for use in the oral cavity, the pH of the oral composition being within the range of from about 5.0 to about 11.0, said composition being free of calcium abrasives which would yield enough soluble calcium to significantly impair the anticalculus activity of said polyphosphonate.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1982-03-05 | 1982-09-04 | 1983-03-06 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1986-03-05 | 1986-09-04 | 1987-03-06 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1990-03-05 | 1990-09-04 | 1991-03-06 | $7700.00 | Window Closed / Lapsed |