Patent US4423061A successfully refreshed from Google Patents.
US4423061A
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Perfluorocycloamine emulsion preparation
Assignee: Tanabe Pharma Corp
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Filing: 1982-12-28
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Granted: 1983-12-27
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Expires: 2002-12-28
Abstract
Abstract A perfluorocycloamine emulsion preparation having oxygen carrying ability containing a perfluorocycloamine of the general formula: <IMAGE> wherein any position may optionally be substituted with a perfluoromethyl group as an oxygen carrying component.
Inventors
- 👤 Kazumasa Yokoyama
- 👤 Chikara Fukaya
- 👤 Yoshio Tsuda
- 👤 Taizo Ono
- 👤 Yoshio Arakawa
- 👤 Yoshihisa Inoue
- 👤 Youichiro Naito
- 👤 Tadakazu Suyama
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 19:18
CPC Classifications
C; C07; C07D; C07D207/00; C07D207/02; C07D207/04; C07D207/10; A; A61; A61P; A61P7/00; A61P7/08
Claims Analysis
Total Claims: 7
Claim 1
Independent Claim
60 words
A perfluorocycloamine emulsion preparation having oxygen carrying ability comprising 5-50% (w/v) of perfluorocycloamine of the general formula ##STR4## wherein any position may optionally be substituted with a perfluoromethyl group, as an oxygen carrying component, 1-5% (w/v) of an emulsifying agent and a balance of a physiologically acceptable aqueous solution, and the emulsion having a particle diameter of 0.3μ or less.
Claim 2
Dependent Claim
60 words
A perfluorocycloamine emulsion preparation having oxygen carrying ability comprising 5-50% (w/v) of perfluorocycloamine of the general formula ##STR4## wherein any position may optionally be substituted with a perfluoromethyl group, as an oxygen carrying component, 1-5% (w/v) of an emulsifying agent and a balance of a physiologically acceptable aqueous solution, and the emulsion having a particle diameter of 0.3μ or less.
Claim 3
Dependent Claim
17 words
A preparation according to claim 1, wherein the perfluorocycloamine is perfluoro-N-cyclohexylpyrrolidine, perfluoro-N-(3'-methylcyclohexyl)pyrrolidine, perfluoro-N-cyclohexyl-2-methylpyrrolidine, perfluoro-N-cyclohexyl-3-methylpyrrolidine, perfluoro-N-(2-methylcyclohexyl)pyrrolidine or perfluoro-N-(4'-methylcyclohexyl)pyrrolidine.
Claim 4
Dependent Claim
18 words
A preparation according to claim 1, wherein the emulsifying agent is a polymeric nonionic surfactant and a phospholipid.
Claim 5
Dependent Claim
29 words
A preparation according to claim 1, wherein 0.001-0.01% (w/v) of a fatty acid having 8-22 carbon atoms or a physiologically acceptable salt thereof is added as an emulsifying agent.
Claim 6
Dependent Claim
16 words
A preparation according to claim 1, wherein an isotonizing amount of an isotonizing agent is added.
Claim 7
Dependent Claim
12 words
A preparation according to claim 1, wherein a plasma extender is added.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1986-12-26 | 1987-06-27 | 1987-12-27 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1990-12-26 | 1991-06-27 | 1991-12-27 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1994-12-26 | 1995-06-27 | 1995-12-27 | $7700.00 | Window Closed / Lapsed |