Patent US4421665A successfully refreshed from Google Patents.
US4421665A
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US
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Contact lens cleaning composition containing lipid solvent and method of using
Assignee: Individual
•
Filing: 1981-01-19
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Granted: 1983-12-20
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Expires: 2001-01-19
Abstract
Abstract A composition for cleaning lenses which includes a non-polar solvent in the form of cyclohexane and/or ethyl acetate with a trace amount of an organic solvent in the form of chloroform or ethyl acetate and a polar solvent in the form of an alcohol. The composition further includes thimerosal, a wetting agent, a surfactant, and a buffer. The composition is provided as a saline solution.
Inventors
- 👤 Eugene A. Lloyd
- 👤 Peter Madri
- 👤 William J. Closson
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-29 21:08
CPC Classifications
C; C11; C11D; C11D7/00; C11D7/50; A; A61; A61L; A61L12/00; A61L12/08; A61L12/14; A61L12/148; C11D3/00; C11D3/0005; C11D3/0078; C11D3/43
Claims Analysis
Total Claims: 47
Claim 1
Independent Claim
37 words
A composition suitable for cleaning lenses and adapted to provide for enhanced solubility of lipids and lipoproteins which comprises in aqueous solution 0.001 to 1.0% by volume of a non-polar solvent which is cyclohexane or ethyl acetate.
Claim 2
Dependent Claim
37 words
A composition suitable for cleaning lenses and adapted to provide for enhanced solubility of lipids and lipoproteins which comprises in aqueous solution 0.001 to 1.0% by volume of a non-polar solvent which is cyclohexane or ethyl acetate.
Claim 3
Dependent Claim
17 words
A composition as claimed in claim 1 which further comprises an additional organic solvent which is chloroform.
Claim 4
Dependent Claim
21 words
A composition as claimed in claim 2 wherein the additional organic solvent is present in an amount of 0.0001-0.01% by volume.
Claim 5
Dependent Claim
21 words
A composition as claimed in claim 3 which further comprises an alcohol selected from the group consisting of ethanol and isopropanol.
Claim 6
Dependent Claim
19 words
A composition as claimed in claim 4 wherein the non-polar solvent is a mixture of cyclohexane and ethyl acetate.
Claim 7
Dependent Claim
19 words
A composition as claimed in claim 4 wherein the alcohol is present in an amount of 0.1-10% by volume.
Claim 8
Dependent Claim
13 words
A composition as claimed in claim 4 which further comprises NaCl or KCl.
Claim 9
Dependent Claim
15 words
A composition as claimed in claim 4 wherein the aqueous solution consists of normal saline.
Claim 10
Dependent Claim
16 words
A composition as claimed in claim 8 wherein the saline is 0.85-0.95 weight percent of NaCl.
Claim 11
Dependent Claim
12 words
A composition as claimed in claim 7 which further comprises a surfactant.
Claim 12
Dependent Claim
23 words
A composition as claimed in claim 10 wherein the surfactant is a non-ionic surfactant present in an amount of about 0.0001-10% by weight.
Claim 13
Dependent Claim
17 words
A composition as claimed in claim 10 wherein the surfactant is a salt of a fatty acid.
Claim 14
Dependent Claim
27 words
A composition as claimed in claim 10 wherein the surfactnt is selected from the group consisting of octylphenoxypolyethoxyethanol, fatty alcohol ethoxylate, Polyethylene stearate and polyoxyethylene sorbitan monolaurate.
Claim 15
Dependent Claim
13 words
A composition as claimed in claim 7 which further comprises an antimicrobial agent.
Claim 16
Dependent Claim
13 words
A composition as claimed in claim 14 wherein the antimicrobial agent is thimerosal.
Claim 17
Dependent Claim
20 words
A composition as claimed in claim 15 wherein the thimerosal is present in an amount of about 0.0005-0.7% by weight.
Claim 18
Dependent Claim
20 words
A composition as claimed in claim 15 wherein the thimerosal is present in an amount of about 0.004% by weight.
Claim 19
Dependent Claim
27 words
A composition as claimed in claim 7 which further comprises a wetting agent selected from the group consisting of polyvinyl alcohol, methylcellulose, hydroxypropylmethycellulose, dextran and polyethyleneglycol homopolymers.
Claim 20
Dependent Claim
21 words
A composition as claimed in claim 18 wherein the wetting agent is present in the amount of about 0.05-10% by weight.
Claim 21
Dependent Claim
20 words
A composition as claimed in claim 7 which further comprises a buffer to adjust the pH range to about 5-10.
Claim 22
Dependent Claim
19 words
A composition as claimed in claim 20 wherein the buffer is a sodium or potassium phosphate, citrate or borate.
Claim 23
Dependent Claim
84 words
A composition as claimed in claim 5 wherein the composition consists essentially of: 0.001-1.0% by volume of said cyclohexane or ethyl acetate 0.1-10% by volume of said ethanol 0.0001-0.01% by volume of said chloroform q.s. to 100% by volume of normal saline 0.0001-10% by weight of a physiologically acceptable surfactant 0.05-10% by weight of a physiologically acceptable wetting agent selected from the group consising of polyvinyl alcohol, methylcellulose, hydroxypropylmethycellulose, dextran and polyethyleneglycol homopolymers, 0.05-1.0% by weight of a buffer 0.0005-0.7% by weight of thimerosal.
Claim 24
Independent Claim
36 words
A method for the cleaning of a contact lens comprising applying to the lens a composition which includes in aqueous solution 0.001 to 1.0% by volume of a non-polar solvent which is cyclohexane or ethyl acetate.
Claim 25
Independent Claim
36 words
A method for the cleaning of a contact lens comprising applying to the lens a composition which includes in aqueous solution 0.001 to 1.0% by volume of a non-polar solvent which is cyclohexane or ethyl acetate.
Claim 26
Dependent Claim
21 words
A method as claimed in claim 23 wherein the non-polar solvent is present in an amount of about 0.02-0.3% by volume.
Claim 27
Dependent Claim
24 words
A method as claimed in claim 23 wherein the composition includes at least one alcohol selected from the group consisting of ethanol and isopropanol.
Claim 28
Dependent Claim
12 words
A method as claimed in claim 25 wherein the alcohol is ethanol.
Claim 29
Dependent Claim
19 words
A method as claimed in claim 26 wherein the composition further includes an additional organic solvent which is chloroform.
Claim 30
Dependent Claim
20 words
A method as claimed in claim 27 wherein the chloroform is present in an amount of about 0.0001-0.01% by volume.
Claim 31
Dependent Claim
15 words
A method as claimed in claim 28 wherein the composition further includes NaCl or KCl.
Claim 32
Dependent Claim
19 words
A method as claimed in claim 28 wherein the non-polar solvent is a mixture of cyclohexane and ethyl acetate.
Claim 33
Dependent Claim
24 words
A method as claimed in claim 28 wherein the aqueous solution consists of normal saline and the saline is 0.85-0.95 weight percent of NaCl.
Claim 34
Dependent Claim
30 words
A method as claimed in claim 28 wherein the composition further includes a wetting agent selected from the group consisting of polyvinyl alcohol, methylcellulose, hydroxypropylmethycellulose, dextran and polyethylene glycol homopolymers.
Claim 35
Dependent Claim
21 words
A method as claimed in claim 32 wherein the wetting agent is present in the amount of about 0.05-10% by weight.
Claim 36
Dependent Claim
14 words
A method as claimed in claim 33 wherein the wetting agent is polyvinyl alcohol.
Claim 37
Dependent Claim
18 words
A method as claimed in claim 28 wherein the composition further includes about 0.0005-0.7% by weight of thimerosal.
Claim 38
Dependent Claim
20 words
A method as claimed in claim 35 wherein the thimerosal is present in an amount of about 0.004% by weight.
Claim 39
Dependent Claim
14 words
A method as claimed in claim 28 wherein the composition further includes a surfactant.
Claim 40
Dependent Claim
23 words
A method as claimed in claim 37 wherein the surfactant is a non-ionic surfactant present in an amount of about 0.0001-10% by weight.
Claim 41
Dependent Claim
12 words
A method as claimed in claim 38 wherein the surfactant is octylphenoxypolyethoxyethanol.
Claim 42
Dependent Claim
17 words
A method as claimed in claim 38 wherein the surfactant is a salt of a fatty acid.
Claim 43
Dependent Claim
22 words
A method as claimed in claim 28 wherein the composition further includes a buffer to adjust the pH range to about 7.1-7.4.
Claim 44
Dependent Claim
42 words
A method as claimed in claim 27 wherein the composition consists essentially of: 0.001-1.0% by volume of said cyclohexane or ethyl acetate 0.1-10% by volume of said ethanol 0.0001-0.01% by volume of said chloroform q.s. to 100% by volume of normal saline
Claim 45
Dependent Claim
42 words
0001-10% by weight of a physiologically acceptable surfactant 0.05-10% by weight of a physiologically acceptable wetting agent selected from the group consisting of polyvinyl alcohol, methylcellulose, hydroxypropylmethycellulose, dextran and polyethyleneglycol homopolymers, 0.05-1.0% by weight of a buffer 0.0005-0.7% by weight of thimerosal.
Claim 46
Dependent Claim
42 words
0001-10% by weight of a physiologically acceptable surfactant 0.05-10% by weight of a physiologically acceptable wetting agent selected from the group consisting of polyvinyl alcohol, methylcellulose, hydroxypropylmethycellulose, dextran and polyethyleneglycol homopolymers, 0.05-1.0% by weight of a buffer 0.0005-0.7% by weight of thimerosal.
Claim 47
Dependent Claim
28 words
A method as claimed in claim 42 wherein the surfactant is selected from the group consisting of octylphenoxypolyethoxyethanol, dioctylsulfosuccinate, fatty alcohol ethoxylate, polyethylene stearate and polyoxyethylene sorbitan monolaurate.
References Cited (Backward Citations)
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1986-12-19 | 1987-06-20 | 1987-12-20 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1990-12-19 | 1991-06-20 | 1991-12-20 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1994-12-19 | 1995-06-20 | 1995-12-20 | $7700.00 | Window Closed / Lapsed |