Patent US4711244A successfully refreshed from Google Patents.
Patent US2689285A successfully refreshed from Google Patents.
Patent US4419346A successfully refreshed from Google Patents.
US4419346A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Method and composition to inhibit the growth of Streptococcus mutans by the use of saccharin/fluoride combination
Assignee: Nabisco Brands Inc
•
Filing: 1982-08-13
•
Granted: 1983-12-06
•
Expires: 2002-08-13
Abstract
Abstract A method and composition for treating teeth to reduce dental caries is provided wherein the teeth are contacted with a synergistic combination of a saccharin material, and a fluoride material, for example, as contained in a chewing gum composition, the combination of saccharin material and fluoride material being present in an amount sufficient to inhibit growth of Streptococcus mutans in the presence of a fermentable carbohydrates in the oral cavity.
Inventors
- 👤 John J. Stroz
- 👤 Andrew M. Slee
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-24 20:34
CPC Classifications
A; A61; A61Q; A61Q11/00; A61K; A61K8/00; A61K8/18; A61K8/19; A61K8/20; A61K8/21; A61K8/30; A61K8/49; A61P; A61P1/00; A61P1/02
Claims Analysis
Total Claims: 6
Claim 1
Independent Claim
74 words
In the method of inhibiting the growth of Streptococcus mutans by contacting Steptococcus mutans with a saccharin compound selected from the group consisting of sodium saccharin, ammonium saccharin, calcium saccharin, or the free acid form of saccharin in an amount sufficient to inhibit growth of Streptococcus mutans, the improvement comprising contacting Streptococcus mutans with said saccharin in synergistic combination with a fluoride material in an amount which inhibits or prevents growth of Streptoccus mutans.
Claim 2
Dependent Claim
74 words
In the method of inhibiting the growth of Streptococcus mutans by contacting Steptococcus mutans with a saccharin compound selected from the group consisting of sodium saccharin, ammonium saccharin, calcium saccharin, or the free acid form of saccharin in an amount sufficient to inhibit growth of Streptococcus mutans, the improvement comprising contacting Streptococcus mutans with said saccharin in synergistic combination with a fluoride material in an amount which inhibits or prevents growth of Streptoccus mutans.
Claim 3
Dependent Claim
42 words
The method of claim 1 wherein said saccharin is contacted with Streptococcus mutans in a composition having no more than 1.0% saccharin and said fluoride material is present in said composition in an amount of no more than 100 ppm of fluoride.
Claim 4
Dependent Claim
43 words
The method of claim 2 wherein said saccharin is present in said composition in an amount of no more than about 0.2% saccharin and said fluoride material present in said composition in an amount of no more than about 10 ppm of fluoride.
Claim 5
Dependent Claim
41 words
The method of claim 3 wherein said saccharin is present in said composition in an amount of no more than about 0.05% saccharin and said fluoride material is present in said composition in an amount of at least 0.2 ppm fluoride.
Claim 6
Dependent Claim
21 words
The method of claim 1 wherein said synergistic combination is contacted with Streptococcus mutans for a period of about 30 minutes.
References Cited (Backward Citations)
US2627493A
Cited
US2913373A
Cited
US3119743A
Cited
US3075884A
Cited
US3282792A
Cited
US3227618A
Cited
US3431339A
Cited
US3531564A
Cited
US3590120A
Cited
US4078053A
Cited
US4291045A
Cited
US4118471A
Cited
FR2420970A2
Cited
US4265877A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1986-12-05 | 1987-06-06 | 1987-12-06 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1990-12-05 | 1991-06-06 | 1991-12-06 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1994-12-05 | 1995-06-06 | 1995-12-06 | $7700.00 | Window Closed / Lapsed |