Patent US2721839A successfully refreshed from Google Patents.
US4078053A
Expired / Lapsed
US
⏱️ 0.0 years remaining
High-concentration fluoride preparations and use for preventing caries
Assignee: ADA Forsyth Institute Inc
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Filing: 1976-02-20
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Granted: 1978-03-07
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Expires: 1996-02-20
Abstract
Abstract High-concentration fluoride containing preparations, particularly ammonium fluoride, in mouth rinses at a concentration of greater than 2000 ppm significantly inhibit caries, particularly by frequent; e.g., daily, use in connection with new, erupting teeth of children.
Inventors
- 👤 Paul F. DePaola
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-25 12:52
CPC Classifications
A; A61; A61Q; A61Q11/00; A61K; A61K8/00; A61K8/18; A61K8/19; A61K8/20; A61K8/21
Claims Analysis
Total Claims: 17
Claim 1
Independent Claim
50 words
A method for the prevention of caries in newly erupted teeth of a subject, which method comprises contacting the newly erupted teeth in the oral cavity daily about four to seven times a week with a composition containing a high concentration of from 500 to 3000 ppm of ammonium fluoride.
Claim 2
Independent Claim
50 words
A method for the prevention of caries in newly erupted teeth of a subject, which method comprises contacting the newly erupted teeth in the oral cavity daily about four to seven times a week with a composition containing a high concentration of from 500 to 3000 ppm of ammonium fluoride.
Claim 3
Dependent Claim
33 words
The method of claim 1 which includes contacting the newly erupted teeth by rinsing the oral cavity with an aqeuous flavored mouth-rinse solution containing about 500 to 1200 ppm of the ammonium fluoride.
Claim 4
Dependent Claim
31 words
The method of claim 1 which includes contacting the newly erupted teeth by brushing the teeth with a composition which comprises a gel-like or paste-like mixture containing a water-insoluble polishing agent.
Claim 5
Dependent Claim
37 words
The method of claim 1 which includes rinsing the mouth daily with about 1 to 20 ml of an aqueous acidic flavored mouth-rinse solution at a pH of about 4.4 containing about 1000 ppm of ammonium fluoride.
Claim 6
Dependent Claim
65 words
The method of claim 1 which includes rinsing the oral cavity containing newly erupted teeth with a mouth-rinse solution which comprises: ______________________________________
Distilled water 1000 ml
Ammonium fluoride
2.0 grams
Phosphoric acid 100 to 600 mg
Sodium saccharin
400 to 1200 mg
Preservative 500 to 2000 mg
Dye 1 to 25 mg
Miscible surfactant
200 to 2000 mg
Flavoring agent 100 to 2000 Mg.
______________________________________
Claim 7
Dependent Claim
23 words
The method of claim 1 wherein the subject is a child of an age of from about 8 to 10 years of age.
Claim 8
Dependent Claim
13 words
The method of claim 1 wherein the composition is an acidic mouth-rinse solution.
Claim 9
Dependent Claim
21 words
The method of claim 1 wherein the composition comprises a transparent gel-like or a paste-like dentifrice containing a water-insoluble polishing agent.
Claim 10
Dependent Claim
17 words
The method of claim 1 wherein such contacting occurs for a period of greater than 1 year.
Claim 11
Independent Claim
67 words
A method for prevention of caries in newly erupted teeth in the oral cavity of children under the age of about 12 years, which method comprises: rinsing the oral cavity with an aqueous-flavored buffered mouth-rinse solution having as active ingredients from about 800 to 1200 ppm of ammonium fluoride, the rinsing occurring daily at least four times a week for a period of at least 1 year.
Claim 12
Independent Claim
67 words
A method for prevention of caries in newly erupted teeth in the oral cavity of children under the age of about 12 years, which method comprises: rinsing the oral cavity with an aqueous-flavored buffered mouth-rinse solution having as active ingredients from about 800 to 1200 ppm of ammonium fluoride, the rinsing occurring daily at least four times a week for a period of at least 1 year.
Claim 13
Dependent Claim
38 words
A mouth-rinse solution for frequent rinsing of an oral cavity of a subject containing newly erupted teeth, which solution comprises an aqueous-flavored buffered solution containing as an active ingredient from about 500 to 3000 ppm of ammonium fluoride.
Claim 14
Dependent Claim
38 words
A mouth-rinse solution for frequent rinsing of an oral cavity of a subject containing newly erupted teeth, which solution comprises an aqueous-flavored buffered solution containing as an active ingredient from about 500 to 3000 ppm of ammonium fluoride.
Claim 15
Dependent Claim
15 words
The solution of claim 11 wherein the ammonium fluoride amount is 800 to 1200 ppm.
Claim 16
Dependent Claim
20 words
The solution of claim 11 which comprises a phosphate buffer to buffer the solution at a pH of about 4.4.
Claim 17
Dependent Claim
53 words
The solution of claim 11 wherein the solution comprises: ______________________________________
Distilled water 1000 ml
Ammonium fluoride
2.0 grams
Phosphoric acid 100 to 600 mg
Sodium saccharin
400 to 1200 mg
Preservative 500 to 2000 mg
Dye 1 to 25 mg
Miscible surfactant
200 to 2000 mg
Flavoring agent 100 to 2000 mg.
______________________________________
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1981-03-06 | 1981-09-05 | 1982-03-07 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1985-03-06 | 1985-09-05 | 1986-03-07 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1989-03-06 | 1989-09-05 | 1990-03-07 | $7700.00 | Window Closed / Lapsed |