Patent US4387242A successfully refreshed from Google Patents.
US4387242A
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Hypocholesterolemic fermentation products and process of preparation
Assignee: Merck and Co Inc
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Filing: 1981-08-21
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Granted: 1983-06-07
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Expires: 2001-08-21
Abstract
Abstract Substances isolated after cultivation of a microorganism belonging to the genus Aspergillus in a culture medium include a compound with structural formula: ##STR1## Together with the corresponding free acid of the above ester, its salts and lactone, compound I is a member of a class of hypocholesterolemic and hypolipemic medicaments.
Inventors
- 👤 Tony Y. K. Lam
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 17:58
CPC Classifications
C; C07; C07D; C07D309/00; C07D309/16; C07D309/28; C07D309/30; C07C; C07C59/00; C07C59/40; C07C59/42; C07C59/46
Claims Analysis
Total Claims: 4
Claim 1
Independent Claim
66 words
A compound of structural formula: ##STR5## in substantially pure form or the corresponding hydroxy acid II in substantially pure form ##STR6## or a pharmaceutically acceptable salt of compound II or a C 1--3 alkyl ester of II, or a substituted C 1--3 alkyl ester of II wherein the substituent is phenyl, dimethylamino, or acetylamino, wherein the salts and esters of II are in substantially pure form.
Claim 2
Dependent Claim
66 words
A compound of structural formula: ##STR5## in substantially pure form or the corresponding hydroxy acid II in substantially pure form ##STR6## or a pharmaceutically acceptable salt of compound II or a C 1--3 alkyl ester of II, or a substituted C 1--3 alkyl ester of II wherein the substituent is phenyl, dimethylamino, or acetylamino, wherein the salts and esters of II are in substantially pure form.
Claim 3
Dependent Claim
13 words
The compound of claim 1 with structural formula: ##STR7## in substantially pure form.
Claim 4
Dependent Claim
13 words
The compound of claim 1 with structural formula: ##STR8## in substantially pure form.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1986-06-06 | 1986-12-06 | 1987-06-07 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1990-06-06 | 1990-12-06 | 1991-06-07 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1994-06-06 | 1994-12-06 | 1995-06-07 | $7700.00 | Window Closed / Lapsed |