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US4356100A Expired / Lapsed US ⏱️ 0.0 years remaining

Soft contact lens cold disinfectant solution

Assignee: Sherman Labs
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Filing: 1979-05-10
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Granted: 1982-10-26
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Expires: 1999-05-10
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Abstract

Abstract An aqueous composition for cleaning rinsing and cold disinfecting of soft contact lenses during non-wearing periods is provided. The composition comprises a polyoxyethylene-polyoxypropylene block copolymer having a molecular weight between about 1,100 and 14,000, a water solubility in excess of about 10 grams per 100 milliliters, a cloud point in 1% aqueous solution above about 32° C. and a foam height in excess of 30 millimeters; a physiologically acceptable nonionic surface acting agent having a water solubility in excess of one gram per 100 milliliters, a cloud point in 1% aqueous solution of from about 65° C. to about 100° C. and a foam height in excess of 25 millimeters; a humectant, preservative, antimicrobial and fungal growth inhibitor composition which is physiologically compatible and compatible with soft and semi-hard contact lenses which includes ascorbic acid in a concentration of from about 0.1 percent to about 10.0 percent of the total aqueous composition.

Inventors

  • 👤 Guy J. Sherman

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-28 13:45
CPC Classifications
A; A61; A61L; A61L12/00; A61L12/08; A61L12/14; A61L12/148; A01; A01N; A01N55/00; A01N55/02; A01N55/06

Claims Analysis

Total Claims: 9
Claim 1
Independent Claim 247 words
A sterile, aqueous composition consisting essentially of water, from about 0.1% to about 8.6% by weight of said total aqueous composition of a polyoxypropylene-polyoxyethylene block copolymer having a molecular weight of about 1,100 to about 14,000, a water solubility in excess of about 10 grams per 100 milliliters, a cloud point in 1% aqueous solution above about 32° C. and a foam height in excess of about 32 millimeters, from about 0.05% to about 0.45% by weight of said total aqueous composition of an alkylphenoxy polyethoxy ethanol octylphenol that is a physiologically acceptable non-ionic surface acting agent having a water solubility in excess of about 1 milliliter per 100 milliliters, a cloud point in 1% aqueous solution of from about 65° C. to about 100° C. and a foam height in excess of about 25 millimeters, from about 0.1% to about 10% ascorbic acid by weight of the total aqueous composition, from about 0.001% to about 0.006% Thimerosal by weight of the total aqueous composition, from about 0.2% to about 2.5% propylene glycol by weight of the total aqueous composition, a salt of ethylenediaminetetraacetic acid suitable for use as a preservative and buffer and present in an amount to maintain the pH of the aqueous composition in a range of between about 4.0 and 7.0, which composition disinfects soft and semi-hard contact lenses within four hours, is compatible with soft and semi-hard lenses to allow storage therein and is suitable for cleaning soft and semi-hard contact lenses.
Claim 2
Dependent Claim 247 words
A sterile, aqueous composition consisting essentially of water, from about 0.1% to about 8.6% by weight of said total aqueous composition of a polyoxypropylene-polyoxyethylene block copolymer having a molecular weight of about 1,100 to about 14,000, a water solubility in excess of about 10 grams per 100 milliliters, a cloud point in 1% aqueous solution above about 32° C. and a foam height in excess of about 32 millimeters, from about 0.05% to about 0.45% by weight of said total aqueous composition of an alkylphenoxy polyethoxy ethanol octylphenol that is a physiologically acceptable non-ionic surface acting agent having a water solubility in excess of about 1 milliliter per 100 milliliters, a cloud point in 1% aqueous solution of from about 65° C. to about 100° C. and a foam height in excess of about 25 millimeters, from about 0.1% to about 10% ascorbic acid by weight of the total aqueous composition, from about 0.001% to about 0.006% Thimerosal by weight of the total aqueous composition, from about 0.2% to about 2.5% propylene glycol by weight of the total aqueous composition, a salt of ethylenediaminetetraacetic acid suitable for use as a preservative and buffer and present in an amount to maintain the pH of the aqueous composition in a range of between about 4.0 and 7.0, which composition disinfects soft and semi-hard contact lenses within four hours, is compatible with soft and semi-hard lenses to allow storage therein and is suitable for cleaning soft and semi-hard contact lenses.
Claim 3
Dependent Claim 51 words
The aqueous composition as recited in claim 1 further consisting essentially of a sufficient amount of water soluble salts compatible with ocular tissue and present in a concentration sufficient to provide a solution salt content equivalent to about 0.8% to about 1.8% sodium chloride by weight of the total aqueous composition.
Claim 4
Dependent Claim 21 words
The aqueous composition as recited in claim 2 wherein two essentially neutral water soluble salts are present in the aqueous composition.
Claim 5
Dependent Claim 19 words
The aqueous composition as recited in claim 3 wherein said essentially neutral salts are sodium chloride and potassium chloride.
Claim 6
Dependent Claim 29 words
The aqueous composition as recited in claim 1 wherein said surface acting agent is an alkylphenoxy polyethoxy ethanol octylphenol surface acting agent having a molecular weight of about 800.
Claim 7
Dependent Claim 34 words
The aqueous composition as recited in claim 1 wherein said salt of ethylenediaminetetraacetic acid is disodium ethylenediaminetetraacetate present in a concentration of from about 0.5% to about 2.0% by weight of said total composition.
Claim 8
Dependent Claim 18 words
The aqueous composition as recited in claim 1 further consisting essentially of a hydroxyethyl cellulose viscosity building agent.
Claim 9
Dependent Claim 29 words
The composition as recited in claim 1 wherein ascorbic acid is present in the aqueous composition in an amount of about 8.0% by weight of the total aqueous composition.

References Cited (Backward Citations)

US3329607A Cited
US3911107A Cited
US3987163A Cited
US4013576A Cited
US4126587A Cited
US4046706A Cited
US4104187A Cited
US4127423A Cited
US4199469A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1985-10-25 1986-04-26 1986-10-26 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1989-10-25 1990-04-26 1990-10-26 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1993-10-25 1994-04-26 1994-10-26 $7700.00 Window Closed / Lapsed

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