US4340726A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Esters
Assignee: Newport Pharmaceuticals International Inc
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Filing: 1980-03-14
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Granted: 1982-07-20
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Expires: 2000-03-14
Abstract
Abstract There are prepared compounds of the formula <IMAGE> where R1 is alkyl of 1 to 8 carbon atoms and R2 is the ester group of an unsubstituted monocarboxylic acid, aromatic carboxylic acid, aminocarboxylic acid, unsubstituted dicarboxylic acid, phosphoric acid, or nitric acid or a glycoside or an acetaldehyde acetal. The compounds are immunomodulators, have antiviral activity and antitumor activity and also are enzyme inhibitors. The compounds can also be used to introduce the corresponding alcohol into biological systems, in some cases with enhanced potency.
Inventors
- 👤 Lionel N. Simon
- 👤 Alfredo Giner-Sorolla
- 👤 Alvin Guttag
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-02 23:02
CPC Classifications
C; C07; C07D; C07D473/00; A; A61; A61P; A61P31/00; A61P31/12; A61P35/00; A61P37/00; A61P37/02; A61P37/04; A61P37/06; C07D473/26; C07D473/28; C07D473/30
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
70 words
A compound of the formula ##STR38## wherein R 1 is an n-hexyl group and R 2 is the ester group of formic acid, acetic acid, propionic acid or butyric acid, phenylalkanoic acid having 2 to 3 carbon atoms in the alkanoic acid portion, salicylic acid, a hemi ester of an alkanedioic or alkenedioic acid, phosphoric acid, nitric acid, or a glycoside of a sugar having 5 to 6 carbon atoms.
Claim 2
Dependent Claim
70 words
A compound of the formula ##STR38## wherein R 1 is an n-hexyl group and R 2 is the ester group of formic acid, acetic acid, propionic acid or butyric acid, phenylalkanoic acid having 2 to 3 carbon atoms in the alkanoic acid portion, salicylic acid, a hemi ester of an alkanedioic or alkenedioic acid, phosphoric acid, nitric acid, or a glycoside of a sugar having 5 to 6 carbon atoms.
Claim 3
Dependent Claim
16 words
A compound according to claim 1 wherein R 2 is the ester group of acetic acid.
Claim 4
Dependent Claim
16 words
A compound according to claim 1 wherein R 2 is a hemimalonate, hemifumarate, hemimaleate or hemisuccinate.
Claim 5
Dependent Claim
12 words
A compound according to claim 3 wherein R 2 is a hemisuccinate.
Claim 6
Dependent Claim
12 words
A compound according to claim 1 wherein R 2 is a glucoside.
Claim 7
Dependent Claim
15 words
A compound according to 1 wherein R 2 is the ester group of propionic acid.
Claim 8
Dependent Claim
15 words
A compound according to 1 wherein R 2 is the ester group of propionic acid.
References Cited (Backward Citations)
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Cited
US4138562A
Cited
US4151277A
Cited
US4221910A
Cited
US4221909A
Cited
US4321376A
Cited
US4221794A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1985-07-19 | 1986-01-18 | 1986-07-20 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1989-07-19 | 1990-01-18 | 1990-07-20 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1993-07-19 | 1994-01-18 | 1994-07-20 | $7700.00 | Window Closed / Lapsed |