US3862189A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Aralkyl-substituted purines and pyrimidines as antianginal bronchodilator agents
Assignee: Warner Lambert Co LLC
•
Filing: 1973-08-14
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Granted: 1975-01-21
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Expires: 1993-08-14
Abstract
Abstract The present invention relates to compounds of formula I: wherein R1 is hydroxy, methoxy, mercapto, hydrazino, substituted hydrazino, chloro, amino, alkylamino, dialkylamino, hydroxyalkylamino, aralkylamino or substituted aralkylamino and R2 is phenylalkyl having 1 to 3 carbon atoms in the alkyl moiety and at least two alkoxy, alkyl, halogen, hydroxy, nitro, amino, substituted amino, aminomethyl, acylamino, carboxy, carboxyalkyl or hydroxymethyl groups in the benzene ring or naphthylalkyl, tetrahydronaphthylalkyl, quinolylalkyl, tetrahydroquinolylalkyl or isoquinolylalkyl, each having 1 to 3 carbon atoms in the alkyl moiety and pharmaceutically acceptable acid addition salts thereof. These compounds are useful as antianginal or bronchial dilator agents.
Inventors
- 👤 Charles F Schwender
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-02 06:38
CPC Classifications
C; C07; C07D; C07D473/00; C07D239/00; C07D239/02; C07D239/24; C07D239/28; C07D239/46; C07D239/48
Claims Analysis
Total Claims: 19
Claim 1
Independent Claim
15 words
A compound according to claim 1 in which R1 is methoxy and R2 is 3,4-dimethoxybenzyl.
Claim 2
Dependent Claim
15 words
A compound according to claim 1 in which R1 is mercapto and R2 is 3,4-dimethoxybenzyl.
Claim 3
Dependent Claim
15 words
A compound according to claim 1 in which R1 is 1-naphthylmethylamino and R2 is 3,4-dimethoxybenzyl.
Claim 4
Dependent Claim
15 words
A compound according to claim 1 in which R1 is amino and R2 is 3,4-dimethoxybenzyl.
Claim 5
Dependent Claim
15 words
A compound according to claim 1 in which R1 is hydroxy and R2 is 3,4-dimethoxybenzyl.
Claim 6
Dependent Claim
15 words
A compound according to claim 1 in which R1 is benzylamino and R2 is 3,4-dimethoxybenzyl.
Claim 7
Dependent Claim
15 words
A compound according to claim 1 in which R1 is 2-hydroxyethylamino and R2 is 3,4-dimethoxybenzyl.
Claim 8
Dependent Claim
15 words
A compound according to claim 1 in which R1 is chloro and R2 is 3,4-dimethoxybenzyl.
Claim 9
Dependent Claim
15 words
A compound according to claim 1 in which R1 is hydrazino and R2 is 3,4-dimethoxybenzyl.
Claim 10
Dependent Claim
15 words
A compound according to claim 1 in which R1 is 1-propylamino and R2 is 3,4-dimethoxybenzyl.
Claim 11
Dependent Claim
15 words
A compound according to claim 1 in which R1 is chloro and R2 is 2-(3,4-dimethoxyphenyl)ethyl.
Claim 12
Dependent Claim
15 words
A compound according to claim 1 in which R1 is amino and R2 is 2-(3,4-dimethoxyphenyl)ethyl.
Claim 13
Dependent Claim
15 words
A compound according to claim 1 in which R1 is chloro and R2 is 1-naphthylmethyl.
Claim 14
Dependent Claim
15 words
A compound according to claim 1 in which R1 is amino and R2 is 1-naphthylmethyl.
Claim 15
Dependent Claim
15 words
A compound according to claim 1 in which R1 is propylamino and R2 is 1-naphthylmethyl.
Claim 16
Dependent Claim
15 words
A compound according to claim 1 in which R1 is 1-hydroxyethylamino and R2 is 1-naphthylmethyl.
Claim 17
Dependent Claim
15 words
A compound according to claim 1 in which R1 is amino and R2 is 3,4-dimethylbenzyl.
Claim 18
Dependent Claim
15 words
A compound according to claim 1 in which R1 is chloro and R2 is 3,4-dichlorObenzyl.
Claim 19
Dependent Claim
15 words
A compound according to claim 1 in which R1 is amino and R2 is 3,4-dichlorobenzyl.
References Cited (Backward Citations)
US3412093A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1978-01-20 | 1978-07-22 | 1979-01-21 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1982-01-20 | 1982-07-22 | 1983-01-21 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1986-01-20 | 1986-07-22 | 1987-01-21 | $7700.00 | Window Closed / Lapsed |