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US4318985A Expired / Lapsed US ⏱️ 0.0 years remaining

Method and device for detecting glucose concentration

Assignee: Bayer Corp
•
Filing: 1981-01-29
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Granted: 1982-03-09
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Expires: 2001-01-29
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Abstract

Abstract A method and test device for determining the glucose concentration in a test sample containing from 1/2 to 5 percent glucose. The method and test device involve incorporating urea-formaldehyde resin in a carrier matrix and subsequently impregnating the carrier with an enzymatic testing composition which includes glucose oxidase, a peroxidatively-active compound and a chromogen. Contact of the carrier with a glucose-containing test sample produces a detectable response whereby the glucose concentration can be determined.

Inventors

  • 👤 Robert Bauer
  • 👤 Myron C. Rapkin

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-25 20:16
CPC Classifications
C; C12; C12Q; C12Q1/00; C12Q1/54; Y; Y10; Y10S; Y10S435/00; Y10S435/805

Claims Analysis

Total Claims: 12
Claim 1
Independent Claim 57 words
In a test device for detecting the presence of glucose in a test sample, wherein said device comprises a carrier matrix incorporated with glucose oxidase, a peroxidatively-active compound and a chromogen, the improvement wherein the carrier matrix is incorporated with from 0.005 percent to 2.5 percent by weight urea-formaldehyde resin wherein there is formed a cross-linked polymer.
Claim 2
Dependent Claim 57 words
In a test device for detecting the presence of glucose in a test sample, wherein said device comprises a carrier matrix incorporated with glucose oxidase, a peroxidatively-active compound and a chromogen, the improvement wherein the carrier matrix is incorporated with from 0.005 percent to 2.5 percent by weight urea-formaldehyde resin wherein there is formed a cross-linked polymer.
Claim 3
Dependent Claim 14 words
A test device as claimed in claim 1 wherein said carrier matrix is paper.
Claim 4
Dependent Claim 22 words
A test device as claimed in claim 1 wherein the urea-formaldehyde is present in an amount of about 0.01 percent by weight.
Claim 5
Dependent Claim 26 words
A test device as claimed in claim 1 wherein the chromogen is a benzidine-type indicator or a substituted aniline indicator and the peroxidatively-active compound is peroxidase.
Claim 6
Dependent Claim 32 words
A method for determining the glucose concentration in a test sample containing from about 1/2 to 5 percent glucose which comprises contacting said test sample with the test device of claim 1.
Claim 7
Dependent Claim 32 words
A method for determining the glucose concentration in a test sample containing from about 1/2 to 5 percent glucose which comprises contacting said test sample with the test device of claim 2.
Claim 8
Dependent Claim 32 words
A method for determining the glucose concentration in a test sample containing from about 1/2 to 5 percent glucose which comprises contacting said test sample with the test device of claim 3.
Claim 9
Dependent Claim 32 words
A method for determining the glucose concentration in a test sample containing from about 1/2 to 5 percent glucose which comprises contacting said test sample with the test device of claim 4.
Claim 10
Dependent Claim 59 words
A method for preparing the test device of claim 1 which comprises the steps of impregnating a carrier with 0.005 percent to 2.5 percent by weight urea-formaldehyde resin wherein there is formed a cross-linked polymer and subsequently impregnating the carrier with a composition effective to determine the presence of from 1/2 to 5 percent glucose in a test sample.
Claim 11
Dependent Claim 50 words
In a method for preparing a test device for the determination of glucose which includes contacting a carrier with a composition effective to determine said glucose, the improvement wherein said carrier is incorporated with from 0.005 to 2.5 percent by weight urea-formaldehyde resin wherein there is formed a cross-linked polymer.
Claim 12
Dependent Claim 50 words
In a method for preparing a test device for the determination of glucose which includes contacting a carrier with a composition effective to determine said glucose, the improvement wherein said carrier is incorporated with from 0.005 to 2.5 percent by weight urea-formaldehyde resin wherein there is formed a cross-linked polymer.

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1985-03-08 1985-09-07 1986-03-09 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1989-03-08 1989-09-07 1990-03-09 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1993-03-08 1993-09-07 1994-03-09 $7700.00 Window Closed / Lapsed

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