US4294926A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Hypocholesteremic fermentation products and process of preparation
Assignee: MSD TECHNOLOGY LP
•
Filing: 1980-01-23
•
Granted: 1981-10-13
•
Expires: 2000-01-23
Abstract
Abstract Substances isolated after cultivation of a microorganism belonging to the genus Aspergillus in a culture medium comprise a compound designated MSD803 which has the lactone structure: <IMAGE> as well as its free hydroxy acid form. Together with salts and esters of the free acid form, these compounds form a class of highly active hypocholesteremic and hypolipemic medicaments.
Inventors
- 👤 Richard L. Monaghan
- 👤 Alfred W. Alberts
- 👤 Carl H. Hoffman
- 👤 George Albers-Schonberg
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-04 06:05
CPC Classifications
C; C12; C12P; C12P7/00; C12P7/62; C07; C07D; C07D309/00; C07D309/16; C07D309/28; C07D309/30; C12P17/00; C12P17/02; C12P17/06; Y; Y10; Y10S; Y10S435/00; Y10S435/8215; Y10S435/911; Y10S435/913
Claims Analysis
Total Claims: 4
Claim 1
Independent Claim
30 words
A process of producing a compound of the formula: ##STR5## or its corresponding free acid which comprises fermenting a microorganism of the genus Aspergillus terreus and isolating the product thereof.
Claim 2
Dependent Claim
30 words
A process of producing a compound of the formula: ##STR5## or its corresponding free acid which comprises fermenting a microorganism of the genus Aspergillus terreus and isolating the product thereof.
Claim 3
Dependent Claim
24 words
The process of claim 1 in which said microorganism is one deposited in the American Type Culture Collection with accession number 20541 or 20542.
Claim 4
Dependent Claim
27 words
The process of claim 1 in which the said isolation comprises extraction of a clarified aqueous solution of said fermentation mixture with a solvent followed by chromatography.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1984-10-12 | 1985-04-13 | 1985-10-13 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1988-10-12 | 1989-04-13 | 1989-10-13 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1992-10-12 | 1993-04-13 | 1993-10-13 | $7700.00 | Window Closed / Lapsed |